Abstract: A biopsy device includes an acquiring element and a fixation element. The acquiring element has a drill, a sleeve and a handle. The sleeve has first screw threads formed on an outer periphery thereon and is covered on a part of one end of drill. The fixation element has a stylet and a trocar. The stylet has a through hole, and second screw threads are formed on an inner periphery of the through hole. The second screw threads of the through hole are engaged with the first screw threads of the sleeve. The trocar is connected with the through hole for receiving the drill. When the handle is rotated by a force, the acquiring element is moved in the through hole and the torcar relative to the fixation element.