Patents by Inventor Wen-Chuan Lin

Wen-Chuan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10376577
    Abstract: Disclosed herein is a refined product obtained from a rice hull, which consists essentially of a type II arabinogalactan having a number average molecular weight in the range of 56 to 103 kDa. Also disclosed are a process for producing the refined product and use of the refined product for enhancing the biological activity of innate immune cells, as well as for treating allergy and cancer.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: August 13, 2019
    Assignee: China Medical University
    Inventors: Wen-Chuan Lin, Li-Chan Yang, Chang-Chi Hsieh
  • Publication number: 20160060367
    Abstract: Disclosed herein is a refined product obtained from a rice hull, which consists essentially of a type II arabinogalactan having a number average molecular weight in the range of 56 to 103 kDa. Also disclosed are a process for producing the refined product and use of the refined product for enhancing the biological activity of innate immune cells, as well as for treating allergy and cancer.
    Type: Application
    Filed: August 20, 2015
    Publication date: March 3, 2016
    Inventors: Wen-Chuan Lin, Li-Chan Yang, Chang-Chi Hsieh
  • Patent number: 9072770
    Abstract: A pharmaceutical composition useful for hepatoprotection is provided. The composition comprises an effective amount of kinsenoside or a pharmaceutically acceptable salt or ester thereof. An aqueous extract of Anoectochilus spp. is also provided. The extract is substantially free of ethyl acetate-philic components.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: July 7, 2015
    Assignee: CHINA MEDICAL UNIVERSITY
    Inventors: Wen-Chuan Lin, Jin-Bin Wu, Hui-Ya Ho, Wei-Lii Lin, Chang-Chi Hsieh, Hsin-Sheng Tsay
  • Patent number: 8853271
    Abstract: A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and/or promoting the expression of collagen in a mammal is provided.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: October 7, 2014
    Assignee: China Medical University
    Inventors: Jin-Bin Wu, Wen-Chuan Lin, Hui-Ya Ho, Sze-Ying Chen
  • Patent number: 8739049
    Abstract: A vehicle simulation system includes a compiler module, a parser module, a wrapper module, a modeling module, and a simulation module. The compiler module generates object code that is compatible with a first type of operating system based on source code that is executable by a vehicle control module and that is compatible with a second type of operating system. The parser module generates a definitions file and an extensible markup language (XML) file based on the source code and the object code. The wrapper module generates a library file based on the object code and the definitions file. The modeling module generates model-based source code for a virtual model based on the XML file and a user configuration of the virtual model. The simulation module simulates operation of a plant of a vehicle with the virtual model.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: May 27, 2014
    Inventors: Michael A. Kropinski, Minghui Kao, Gary Ferries, Hamid M. Esfahan, Wen-Chuan Lin, Michael A. Steele, Onassis Matthews
  • Patent number: 8569249
    Abstract: Provided is a method for inhibiting the activation of macrophages in a subject, comprising administrating to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable ester of the compound, and combinations thereof:
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: October 29, 2013
    Assignee: China Medical University
    Inventors: Wen-Chuan Lin, Jin-Bin Wu, Hui-Ya Ho, Hung-Bo Hsiao
  • Publication number: 20120277182
    Abstract: An Anoectochilus spp. polysaccharide extract for stimulating the growth of advantageous bacteria, stimulating the release of granulocyte colony-stimulating factor (G-CSF), modulating T helper cell type I (Th1 cell), and/or modulating T helper cell type II (Th2 cell) is provided. The extract comprises an effective amount of a type II arabinogalactan of Anoectochilus spp. Also provided are a method for the preparation of the Anoectochilus spp. polysaccharide extract and the use of the extract.
    Type: Application
    Filed: July 11, 2012
    Publication date: November 1, 2012
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Wen-Chuan LIN, Chang-Chi HSIEH, Ting-Jang LU, Hsin-Sheng TSAY, Li-Chan YANG, Chia-Chieh LIN, Chung-Huang WANG
  • Publication number: 20120238513
    Abstract: Provided is a method for inhibiting the activation of macrophages in a subject, comprising administrating to the subject an effective amount of an active component selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, and a pharmaceutically acceptable ester of the compound, and combinations thereof:
    Type: Application
    Filed: June 15, 2011
    Publication date: September 20, 2012
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: WEN-CHUAN LIN, JIN-BIN WU, HUI-YA HO, HUNG-BO HSIAO
  • Publication number: 20120059059
    Abstract: A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and/or promoting the expression of collagen in a mammal is provided.
    Type: Application
    Filed: November 29, 2010
    Publication date: March 8, 2012
    Inventors: Jin-Bin Wu, Wen-Chuan Lin, Hui-Ya Ho, Sze-Ying Chen
  • Patent number: 8084431
    Abstract: A method for inhibiting the activation of macrophages, inhibiting the formation of osteoclasts, inhibiting the function of osteoclasts, and/or activating osteoblasts in a mammal is provided.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: December 27, 2011
    Assignee: China Medical University
    Inventors: Wen-Chuan Lin, Jin-Bin Wu, Hung-Bo Hsiao, Hui-Ya Ho
  • Publication number: 20110288840
    Abstract: A vehicle simulation system includes a compiler module, a parser module, a wrapper module, a modeling module, and a simulation module. The compiler module generates object code that is compatible with a first type of operating system based on source code that is executable by a vehicle control module and that is compatible with a second type of operating system. The parser module generates a definitions file and an extensible markup language (XML) file based on the source code and the object code. The wrapper module generates a library file based on the object code and the definitions file. The modeling module generates model-based source code for a virtual model based on the XML file and a user configuration of the virtual model. The simulation module simulates operation of a plant of a vehicle with the virtual model.
    Type: Application
    Filed: August 23, 2010
    Publication date: November 24, 2011
    Applicant: GM GLOBAL TECHNOLOGY OPERATIONS, INC.
    Inventors: Michael A. Kropinski, Minghui Kao, Gary Ferries, Hamid M. Esfahan, Wen-Chuan Lin, Michael A. Steele, Onassis Matthews
  • Publication number: 20110142966
    Abstract: A pharmaceutical composition useful for hepatoprotection is provided. The composition comprises an effective amount of kinsenoside or a pharmaceutically acceptable salt or ester thereof. An aqueous extract of Anoectochilus spp. is also provided. The extract is substantially free of ethyl acetate-philic components.
    Type: Application
    Filed: December 13, 2010
    Publication date: June 16, 2011
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Wen-Chuan LIN, Jin-Bin Wu, Hui-Ya Ho, Wei-Lii Lin, Chang-Chi Hsieh, Hsin-Sheng Tsay
  • Publication number: 20110082103
    Abstract: An Anoectochilus spp. polysaccharide extract for stimulating the growth of advantageous bacteria, stimulating the release of granulocyte colony-stimulating factor (G-CSF), modulating T helper cell type I (Th1 cell), and/or modulating T helper cell type II (Th2 cell) is provided. The extract comprises an effective amount of a type II arabinogalactan of Anoectochilus spp. Also provided are a method for the preparation of the Anoectochilus spp. polysaccharide extract and the use of the extract.
    Type: Application
    Filed: March 1, 2010
    Publication date: April 7, 2011
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Wen-Chuan Lin, Chang-Chi Hsieh, Ting-Jang Lu, Hsin-Sheng Tsay, Li-Chan Yang, Chia-Chieh Lin, Chung-Huang Wang
  • Publication number: 20110082197
    Abstract: A method for inhibiting the formation and/or activation of osteoclasts in a mammal comprising administrating an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or ester thereof to the mammal is provided: Also provided is a method for the preparation of a Flemingia macrophylla extract.
    Type: Application
    Filed: March 22, 2010
    Publication date: April 7, 2011
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Jin-Bin Wu, Wen-Chuan Lin, Hui-Ya Ho
  • Publication number: 20090306199
    Abstract: A method for inhibiting the activation of macrophages, inhibiting the formation of osteoclasts, inhibiting the function of osteoclasts, and/or activating osteoblasts in a mammal is provided.
    Type: Application
    Filed: May 11, 2009
    Publication date: December 10, 2009
    Inventors: Wen-Chuan Lin, Jin-Bin Wu, Hung-Bo Hsiao, Hui-Ya Ho
  • Publication number: 20080241283
    Abstract: A pharmaceutical composition useful for hepatoprotection is provided. The composition comprises an effective amount of kinsenoside or a pharmaceutically acceptable salt or ester thereof. An aqueous extract of Anoectochilus spp. is also provided. The extract is substantially free of ethyl acetate-philic components.
    Type: Application
    Filed: September 13, 2007
    Publication date: October 2, 2008
    Applicant: China Medical University
    Inventors: Wen-Chuan Lin, Jin-Bin Wu, Hui-Ya Ho, Wei-Lii Lin, Chang-Chi Hsieh, Hsin-Sheng Tsay
  • Publication number: 20050051553
    Abstract: A re-closure device for a pop-top can is convenient to use, is plastic or metal and has an inside end, an outside end, a bottom protrusion and two opposite sides. The pop-top can has a top lid, an annular lip around the top lid, an opening defined in the top lid and a pull-tab attached to the top lid by a pivot fastener. The inside end connects to the pivot fastener and engages simultaneously the pull-tab. The outside end has a frame that holds onto the annular lip, an outer lip for removing conveniently the re-closure device and a retaining lip extending from the outer lip to engage the annular lip to hold the re-closure device on the top lid. The bottom protrusion is held in and seals the opening.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 10, 2005
    Inventors: Rung-Feng Li, Wen-Chuan Lin