Patents by Inventor Wen Hao Guo

Wen Hao Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240383910
    Abstract: Novel small molecule proteolysis-targeting chimeras (PROTACs) are provided, along with methods for their use as Bruton's tyrosine kinase (BTK) degraders. The small molecule PROTACs described herein are useful in treating and/or preventing BTK-related diseases, such as cancer, neurodegenerative disorders, inflammatory diseases, and metabolic disorders. Also provided are methods for inducing BTK degradation in a cell using the compounds and compositions described herein.
    Type: Application
    Filed: May 15, 2024
    Publication date: November 21, 2024
    Applicant: Baylor College of Medicine
    Inventors: Wen-Hao Guo, Xin Yu, Ran Cheng, Jin Wang
  • Publication number: 20100290207
    Abstract: An emergency light device includes a housing having an upper flange, a barrel having a peripheral rib engaged with the flange for latching the barrel to the housing and having a partition for forming two compartments, a plate disposed in the upper compartment and secured to the barrel and having a number of light members, a circuit board disposed in the lower compartment of the barrel and secured to the barrel and having a control circuit for controlling the light members, and a battery for energizing the light members, the circuit board and the plate may be solidly secured to the partition of the barrel, and the barrel may be quickly attached to the housing and to a hood, and the light device may be used as a flashlight or a hand-held light, and a night light.
    Type: Application
    Filed: May 14, 2009
    Publication date: November 18, 2010
    Inventors: Mao Hua Chan, Li-Hsing Kuan, Wen Hao Guo