Patents by Inventor Wen-Li Chung
Wen-Li Chung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9522174Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: GrantFiled: December 9, 2014Date of Patent: December 20, 2016Assignee: Biogen MA Inc.Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20150093359Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: December 9, 2014Publication date: April 2, 2015Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Patent number: 8932574Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: GrantFiled: July 17, 2013Date of Patent: January 13, 2015Assignee: Biogen Idec MA Inc.Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20130302281Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: July 17, 2013Publication date: November 14, 2013Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Patent number: 8512692Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: GrantFiled: June 4, 2010Date of Patent: August 20, 2013Assignee: Biogen Idec Ma Inc.Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Patent number: 8512691Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: GrantFiled: October 18, 2007Date of Patent: August 20, 2013Assignee: Biogen Idec Ma Inc.Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20120088724Abstract: Formulations containing complexed human growth hormone crystals are described. Also described are needleless injection systems for crystalline proteins.Type: ApplicationFiled: October 10, 2011Publication date: April 12, 2012Applicant: Althea Technologies, Inc.Inventors: Wen-Li Chung, Lawrence Bush, Sergey Pechenov, Sujit K. Basu
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Patent number: 8071544Abstract: Formulations containing complexed human growth hormone crystals are described. Also described are needleless injection systems for crystalline proteins.Type: GrantFiled: December 13, 2007Date of Patent: December 6, 2011Assignee: Althea Technologies, Inc.Inventors: Wen-Li Chung, Lawrence Bush, Sergey Pechenov, Sujit K. Basu
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Publication number: 20100239531Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contract with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: June 4, 2010Publication date: September 23, 2010Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20100216705Abstract: Formulations containing complexed human growth hormone crystals are described. Also described are needleless injection systems for crystalline proteins.Type: ApplicationFiled: December 13, 2007Publication date: August 26, 2010Inventors: Wen-Li Chung, Lawrence Bush, Sergey Pechenov, Sujit K. Basu
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Publication number: 20080050339Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: October 18, 2007Publication date: February 28, 2008Applicant: Biogen Idec MA, Inc.Inventors: Mary DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20080050338Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: October 18, 2007Publication date: February 28, 2008Applicant: Biogen Idec MA, Inc.Inventors: Mary DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20080044381Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: October 18, 2007Publication date: February 21, 2008Applicant: Biogen Idec MA, Inc.Inventors: Mary DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin
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Publication number: 20030190307Abstract: Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.Type: ApplicationFiled: March 24, 2003Publication date: October 9, 2003Applicant: Biogen, Inc.Inventors: Mary D. DiBiase, Wen-Li Chung, Mark Staples, Eric Scharin