Patents by Inventor Wen-Ling Yeh

Wen-Ling Yeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230201279
    Abstract: The invention provides an extracellular vesicle and a nucleotide fragment isolated from Lactobacillus paracasei GM-080 with the deposition number BCRC 910220 and CCTCC M 204012 and use thereof. The invention also relates to a method for modulating immune function comprising administering a composition including the extracellular vesicle and the nucleotide fragment.
    Type: Application
    Filed: March 11, 2022
    Publication date: June 29, 2023
    Inventors: Wan-Hua Tsai, Wen-Wei Chang, Chia-Hsuan Chou, I-Jen Wang, Wen-Ling Yeh, Jhih-Hua Jhong, Tzong-Yi Lee
  • Publication number: 20230081322
    Abstract: The present invention provides a Lactobacillus composition and a use thereof for improving anxiety caused by antibiotics, wherein the Lactobacillus composition comprises Lactobacillus plantarum GMNL-141, Lactobacillus rhamnosus GM-020, Lactobacillus acidophilus GMNL-185, or a combination thereof. The Lactobacillus composition can effectively improve imbalance of an individual's intestinal flora caused by antibiotics to help stabilize and increase species richness and increase the synthesis of mood-stabilizing compounds, including flavonoids, flavonols, isoquinoline alkaloids, niacinamide, nicotinamide, and short-chain fatty acids in intestine, and thus effectively improve antibiotic-induced with anxiety disorders.
    Type: Application
    Filed: December 23, 2021
    Publication date: March 16, 2023
    Inventors: WAN-HUA TSAI, WEN-LING YEH, CHIA-LIN WU, CHIH-HO LAI, YAO-TSUNG YEH, CHENG-HSIEH HUANG
  • Publication number: 20220031775
    Abstract: A probiotic composition for improving an effect of a chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is disclosed in the present disclosure. The probiotic composition comprises an effective amount of Lactobacillus paracasei GMNL-133, an effective amount of Lactobacillus reuteri GMNL-89, and a pharmaceutically acceptable carrier, wherein the Lactobacillus paracasei GMNL-133 was deposited in the China Center for Type Culture Collection on Sep. 26, 2011 under an accession number CCTCC NO. M 2011331, and the Lactobacillus reuteri GMNL-89 was deposited in the China Center for Type Culture Collection on Nov. 19, 2007 under an accession number CCTCC NO. M 207154. A method for improving the effect of the chemotherapeutic drug of Gemcitabine on inhibiting pancreatic cancer is further disclosed in the present disclosure.
    Type: Application
    Filed: May 12, 2021
    Publication date: February 3, 2022
    Inventors: Wan-Hua TSAI, I-ling HSU, Shan-ju HSU, Wen-ling YEH, Ming-shiou JAN, Wee-wei CHIENG, Li-jin HSU, Ying-chun LAI
  • Patent number: 10632160
    Abstract: The present invention relates to a probiotic composition for preventing, improving or alleviating pancreatic cancer and a method for preventing, improving or alleviating the pancreatic cancer and its complications using the probiotic composition. The probiotic composition, which is consisted of specific strains and specific ratio of Lactobacillus paracasei to Lactobacillus reuteri, can significantly improve or alleviate various symptomatic indicators and severity of pancreatic cancer, thereby being applied on a method for preventing, improving or alleviating the pancreatic cancer and its complications using an oral composition including the Lactobacillus strains.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: April 28, 2020
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh, Ming-Shiou Jan, Yen-Wan Hsiao, Li-Jin Hsu, Junko Sugawara
  • Patent number: 10456430
    Abstract: A composition is used for prevention or treatment of bacterial vaginosis (BV) and regulation of vaginal immunity and said composition with effective amount is selected from the groups comprising Lactobacillus rhamnosus GMNL-680 and Lactobacillus plantarum GMNL-682; the composition of the present invention is used to prevent and treat bacterial vaginosis by inhibition of the growth of pathogens and regulation of the expression of immunoregulators and is prepared in the forms of pharmaceutical compositions, food or other combinations thereof.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: October 29, 2019
    Assignee: Genmont Biotech Incorporation
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh
  • Publication number: 20190290707
    Abstract: The present invention relates to a probiotic composition for preventing, improving or alleviating pancreatic cancer and a method for preventing, improving or alleviating the pancreatic cancer and its complications using the probiotic composition. The probiotic composition, which is consisted of specific strains and specific ratio of Lactobacillus paracasei to Lactobacillus reuteri, can significantly improve or alleviate various symptomatic indicators and severity of pancreatic cancer, thereby being applied on a method for preventing, improving or alleviating the pancreatic cancer and its complications using an oral composition including the Lactobacillus strains.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh, Ming-Shiou Jan, Yen-Wan Hsiao, Li-Jin Hsu, Junko Sugawara