Abstract: This application discloses a cloud platform selection method and apparatus. The method includes: obtaining service information, where the service information includes access device information and path requirement information; obtaining a recommendation result of a cloud platform based on the service information, where the recommendation result indicates a cloud platform corresponding to each access device in a first device set, the first device set includes a first access device, the first access device corresponds to a first cloud platform, path requirement evaluation information of a path from the first access device to the first cloud platform meets the path requirement information, the first device set includes M access devices or a part of the M access devices, the cloud platform corresponding to each access device belongs to a candidate cloud platform set, and the candidate cloud platform set includes P cloud platforms; and displaying the recommendation result in a first interface.

Abstract: Partial bandwidth radio transmission method and device, base station and user equipment are provided. The method includes: configuring a first common control channel transmitted on an anchor sub-band; configuring at least one sub-band other than anchor sub-bands, and a second common control channel transmitted on the at least one sub-band; scheduling at least one partial bandwidth UE to the at least one sub-band, and transmitting configuration of the second common control channel and the at least one sub-band to the at least one partial bandwidth UE; and obtaining a transmission time of a synchronization signal block in the anchor sub-band, and transmitting the second common control channel to the at least one sub-band based on the transmission time, wherein the second common control channel includes a reference signal for demodulation. UE can receive and transmit data using partial bandwidth among a relatively large system bandwidth, which improves system efficiency.

Abstract: A water environment temperature measurement tool includes measurement boxes and a counterweight box; a plurality of groups of the measurement boxes are provided; the counterweight box is movably connected with a group of measurement boxes; and each measurement box is provided with a temperature measurement instrument inside. The water environment temperature measurement tool further comprises: control mechanisms, each comprising a water inlet pipe, a water retaining member, an elastic member, a control assembly, a rotating seat, a rotating shaft, a second screw rod, a control seat and a rotary assembly. In the water environment temperature measurement tool of the present invention, the control mechanisms can achieve extraction and temperature measurement of water at different water body depths by cooperating with the measurement boxes and the temperature measurement instruments.

Abstract: A display substrate, a display apparatus and a manufacturing method are provided. The display substrate includes: a base substrate; a first electrode layer on a side of the base substrate; a light-emitting layer on a side of the first electrode layer facing away from the base substrate including a plurality of light-emitting portions; a second electrode layer on a side of the light-emitting layer facing away from the first electrode layer; a first transparent inhibitor layer including a plurality of mutually separated first pattern portions; and an auxiliary electrode layer including an auxiliary electrode pattern formed by inhibition of the first pattern portions, where at least part of an orthographic projection of the auxiliary electrode pattern on the base substrate is separated from orthographic projections of the first pattern portions on the base substrate, and the auxiliary electrode pattern is in contact and electrically connected with the second electrode layer.

Abstract: The present application disclosures a double production line and a rapid prefabrication process of a segmental beam. The double production line including two production machine and a track system provided on the construction ground; the production machine includes a fixed end mold, two side molds, a bottom mold trolley, a middle internal mold trolley and two side internal mold trolley; two side molds are positioned on two sides of the fixed end mold respectively, the fixed end mold and two side molds together define a pouring position with an end opening, two openings of the pouring position are arranged facing each other; the track system includes a transverse track and a longitudinal track communicated with each other, two pouring positions are both positioned in the extension path of the transverse track, and the longitudinal track is positioned between two pouring positions.

Abstract: A device for removing unwanted objects from cut tobacco in a cut tobacco production line is disclosed, which includes: a raw cut tobacco feeding and conveying unit (N1), a heavy unwanted object removal unit (N2), a cut tobacco dispersion and recovery unit (N3), a moderate unwanted object removal unit (N4), a cut tobacco humidification unit (N5) and a light unwanted object removal unit (N6). An unwanted object removal method using the cut tobacco unwanted object removal device is also disclosed. The device and method of the disclosure can effectively remove unwanted objects from cut tobacco.

Abstract: A water environment temperature measurement tool includes measurement boxes and a counterweight box; a plurality of groups of the measurement boxes are provided; the counterweight box is movably connected with a group of measurement boxes; and each measurement box is provided with a temperature measurement instrument inside. The water environment temperature measurement tool further comprises: control mechanisms, each comprising a water inlet pipe, a water retaining member, an elastic member, a control assembly, a rotating seat, a rotating shaft, a second screw rod, a control seat and a rotary assembly. In the water environment temperature measurement tool of the present invention, the control mechanisms can achieve extraction and temperature measurement of water at different water body depths by cooperating with the measurement boxes and the temperature measurement instruments.

Abstract: A press hardening steel by a thin slab casting and direct rolling has a tensile strength of 1500 MPa or more. The press hardening steel has a components by weight percent: C: 0.21-0.25%, Si: 0.26-0.30%, Mn: 1.0-1.3%, P?0.01%, S?0.005%, Als: 0.015-0.060%, Cr: 0.25-0.30%, Ti: 0.026-0.030% or Nb: 0.026-0.030% or V: 0.026-0.030%, or a mixture of two or more of the above in any proportion; B: 0.003-0.004%, and N?0.005%. A method for producing the press hardening steel includes following steps: hot metal desulphurization; electric-furnace or converter smelting and refining; continuous casting; descaling, then entering a soaking furnace; heating and soaking; high-pressure water descaling, then entering a rolling mill; hot rolling; cooling; coiling; austenitizing; die deforming and quenching.

Abstract: The disclosure relates to a compound, having a structure of Formula I or a pharmaceutically acceptable salt thereof, herein, R1 is selected from hydrogen, fluorine, and chlorine; R2 and R3 are independently selected from hydrogen, alkyl, a substituted alkyl, alkenyl or a substituted alkenyl, alkynyl or a substituted alkynyl, and aryl, or R2 and R3 are connected to form a ring selected from a cycloalkyl, a substituted cycloalkyl, an aromatic heterocycle or a non-aromatic heterocycle; R4 is selected from hydrogen, cyano, alkyl, a substituted alkyl, alkenyl or a substituted alkenyl, alkynyl or a substituted alkynyl, and aryl; and R5 is selected from hydrogen, halogen, and haloalkyl. The disclosure further relates to a pharmaceutical composition containing the compound. The compound and the composition of the disclosure show significant activity in an aspect of treating AR-prostate cancer and triple-negative breast cancer.

Abstract: A press hardening steel by a thin slab casting and direct rolling has a tensile strength of 1500 MPa or more. The press hardening steel has a components by weight percent: C: 0.21-0.25%, Si: 0.26-0.30%, Mn: 1.0-1.3%, P?0.01%, S?0.005%, Als: 0.015-0.060%, Cr: 0.25-0.30%, Ti: 0.026-0.030% or Nb: 0.026-0.030% or V: 0.026-0.030%, or a mixture of two or more of the above in any proportion; B: 0.003-0.004%, and N?0.005%. A method for producing the press hardening steel includes following steps: hot metal desulphurization; electric-furnace or converter smelting and refining; continuous casting; descaling, then entering a soaking furnace; heating and soaking; high-pressure water descaling, then entering a rolling mill; hot rolling; cooling; coiling; austenitizing; die deforming and quenching.

Abstract: The present invention relates to use of a camptothecin derivative for preparing a medicament for the treatment of multiple myeloma. The medicament is represented by Formula I and can be pharmaceutically acceptable salts thereof. This medicament shows advantages in treatment of multiple myeloma and avoids drug resistance problems for existing drugs.

Abstract: The present invention relates to a water soluble derivative of camptothecin and preparation method thereof, the derivative having a structure of formula I and being appropriate in water solubility, and having anti-cancer activity and stability of lactonic ring. The present invention also relates to a method for synthesizing the compound and medical use of the compound.

Abstract: The present invention relates to a camptothecin derivative having a structure as represented by Formula (II), in which Xn+ is selected from H+, K+, Na+, Li+, Mg2+, Ca2+, Zn2+, Fe3+, and ammonium ion, while R1, R2, R3, and R4 independently represent a hydrogen, a hydroxyl group, a nitro group, a cyano group, a halogen, a carboxyl group, an optionally substituted amino group, a silicon-containing group, a monocyclic aryloxy group, an optionally substituted C1-C6 alkoxy group, an optionally substituted C1-C6 alkylcarbonyl group, an optionally substituted C1-C6 alkyl group, or an optionally substituted C3-C6 cycloalkyl group; alternatively, R1 and R2 are connected via one to three other atoms to form a heterocyclic ring; and in another embodiment, R3 and R4 are oxygen atoms and connected via —O—(CH2)n—O—, forming a ring, in which n=I or 2. The compound has great water-solubility, chemical stability, and great efficacy in treatment on cancer.

Abstract: The present invention relates to a water soluble derivative of camptothecin and preparation method thereof, the derivative having a structure of formula I and being appropriate in water solubility, and having anti-cancer activity and stability of lactonic ring. The present invention also relates to a method for synthesizing the compound and medical use of the compound.

Abstract: The present invention relates to a camptothecin derivative having a structure as represented by Formula (II), in which Xn+ is selected from H+, K+, Na+, Li+, Mg2+, Ca2+, Zn2+, Fe3+, and ammonium ion, while R1, R2, R3, and R4 independently represent a hydrogen, a hydroxyl group, a nitro group, a cyano group, a halogen, a carboxyl group, an optionally substituted amino group, a silicon-containing group, a monocyclic aryloxy group, an optionally substituted C1-C6 alkoxy group, an optionally substituted C1-C6 alkylcarbonyl group, an optionally substituted C1-C6 alkyl group, or an optionally substituted C3-C6 cycloalkyl group; alternatively, R1 and R2 are connected via one to three other atoms to form a heterocyclic ring; and in another embodiment, R3 and R4 are oxygen atoms and connected via —O—(CH2)n—O—, forming a ring, in which n=I or 2. The compound has great water-solubility, chemical stability, and great efficacy in treatment on cancer.

Abstract: The invention provides compounds capable of treating against hepatitis infections, particularly hepatitis B viral infections. Compounds of the invention are nucleic acid-based and preferably comprise 2, 3, 4, 5 or 6 nucleoside units.

Abstract: The invention provides compounds capable of treating against hepatitis infections, particularly hepatitis B viral infections. Compounds of the invention are nucleic acid-based and preferably comprise 2, 3, 4, 5 or 6 nucleoside units.

Abstract: The invention provides compounds capable of treating against hepatitis infections, particularly hepatitis B viral infections. Compounds of the invention are nucleic acid-based and preferably comprise 2, 3, 4, 5 or 6 nucleoside units.

Abstract: The invention provides compounds capable of treating against hepatitis infections, particularly hepatitis B viral infections. Compounds of the invention are nucleic acid-based and preferably comprise 2, 3, 4, 5 or 6 nucleoside units.

Abstract: The invention provides compounds capable of treating against hepatitis infections, particularly hepatitis B viral infections. Compounds of the invention are nucleic acid-based and preferably comprise 2, 3, 4, 5 or 6 nucleoside units.