Abstract: An optical display has multiple display units overlapped on top of one another. Each display unit includes light holes defined in a front face of the display unit for emission of light, multiple first bosses formed on a top face of the display unit and multiple first grooves defined in a bottom face of the display unit such that two adjacent display units are able to be combined with one another via the extension of the first bosses from one display unit into the first grooves of the other display unit.

Abstract: Five independent transgenic founder lines were created which have all developed cardiac hypertrophy and heart failure. The line with the most severe phenotype was analyzed in detail. Transgenic cardiac 11&bgr;HSD2 mRNA expression is increased 4,000 fold over non-transgenic mice and the expressed enzyme was found to possess catalytic activity. At five months of age transgenic mice had developed severe myocardial hypertrophy in the absence of an increase in blood pressure. Interstitial fibrosis in the left ventricle of transgenic mice was revealed by picrosirius red staining. The hearts of the mice were severely dilated and cardiomyocyte size was increased.