Abstract: The present application provides a method for bluing anthocyanin, including: mixing anthocyanin with a protein to obtain a mixed solution; and bluing the anthocyanin through standing treatment of the mixed solution. The method includes no high hydrostatic pressure treatment. A concentration of the anthocyanin in the mixed solution ranges from 0.05 mM to 0.2 m. The anthocyanin is cyanidin-3-glucoside, the protein is selected from human serum albumin or lysozyme, a final concentration of the human serum albumin, if present, in the mixed solution ranges from 0.1 mM to 2 mM, and a final concentration of the lysozyme, if present, ranges from 0.8 mM to 1.5 mM. Alternatively, the anthocyanin is malvidin-3-glucoside, the protein is selected from human serum albumin or bovine serum albumin, and the final concentration ranges from 0.1 mM to 0.5 mM. A pH value of the mixed solution ranges from 5.0 to 9.0.

Abstract: A polymer compound modified by an acryloyl derivative and a polythiol compound are used for preparing a thiol-modified polymer compound by a Michael addition reaction of thiol and conjugated double bonds.

Abstract: An emulation system traverses trace buffers to read data captured from a design under test (DUT). The emulation system receives a request to read at least a portion of DUT data. The emulation system reads a header of the latest sample of the DUT data, where header of each sample of the DUT data includes one or more pointers to a previously stored sample. The samples of the DUT data are partitioned into frames and sectors. The emulation system can identify samples of the DUT data using the pointers in the header of the samples and compare time stamps of the samples against a specified time stamp in the received request. After identifying a sample having the specified time stamp, the emulation system may read the sample for output to the user (e.g., reconstructing a waveform using the sample).

Abstract: A sulfhydryl modified hyaluronic acid has a high mercaptan content, and a small change in the molecular mass of the main chain molecule, and has a significantly improved viscosity, water retention, and oxidation resistance. It is prepared from hyaluronic acid modified by acryl-based compounds and polysulfhydryl compounds by means of the Michael addition reaction of mercaptan and conjugated double bonds. The preparation method can flexibly control the structure and composition of a synthesized product, the type and content of the terminal functional group of a large number of compound molecules, etc. The use of a reagent having high biocompatibility effectively controls the production cost and reduces the toxicity during the synthesis.

Abstract: A preparation method of a hydrogel of a mercapto-modified macromolecular compound includes the steps of combining the mercapto-modified macromolecular compound with an acrylated macromolecular compound and/or an acrylated micromolecular crosslinker. The mercapto-modified macromolecular compound can be crosslinked with the acrylated macromolecular compound and/or the acrylated micromolecular crosslinker under physiological conditions to form the hydrogel. Due to the rapid mercapto-vinyl crosslinking reaction, the formed hydrogel system can be quickly gelled in situ after being injected into the body. The hydrogel is thus suitable for use in the fields of biomedicine, medical cosmetic plastic surgery and cosmetics.

Abstract: Hyperbranched cationic polymers are described. The polymers employ a 4-branching monomer resulting in an increase in the number of functional terminal groups due to the extra branching units, providing excellent transfection efficiency and cytocompatibility in different cell types, including aADSC, HeLa, Neu7 and RDEB keratinocytes, and delivering different genetic therapy approaches such GFP plasmid DNA and a ribonucleoprotein CRISP-Cas 9 complex for COL7A1 exon 80 skipping. In addition, the extra branching units of the polymer of the invention increases the positive charge on the polymer, which provides for improved endosomal escape within the cell. The 4-branching unit can be a diamine component, or a tetraacrylate component, although other 4-branching monomers may be employed such as for example any component with tetra acrylamide groups (i.e. 4-arm PEG acrylamide, 4-arm PEG maleimide), any component with tetra N- hydroxysuccinimide (NHS) groups (i.e.

Abstract: A nanoparticulate composition comprises a gene editing ribonucleoprotein system complexed within a cationic polymer. The cationic polymer may be a Poly-beta amino ester hyperbranched polymer, especially a 4-branching hyperbranched polymer. The gene editing ribonucleoprotein system may be a CRISPR-Cas9 gene editing system configured to excise a mutation or exon in a gene, replace a mutation in a gene, or produce a knock-down or knock-out of a gene, and in particular configured to excise exon 80 of the COL7A1 gene which codes for the collagen VII protein.

Abstract: The present disclosure relates to branched polymers and polyplexes which find use in gene therapy applications as safe and non-toxic nucleic acid transfection agents.

Abstract: A system for staring a large-scale power load in a micro grid comprises a PCC grid connection switch, a micro grid alternating-current bus, an active power filter (APF), an energy storage inverter, an energy storage battery, a current-limiting resistor R, contactors K1-K3, a time relay KT, a power supply relay board, a micro grid maser control system, a frequency converter rectifying circuit, a frequency converter filter circuit, and a frequency converter inverter circuit. There are the advantages: an output torque of a power load can be effectively improved by using a variable frequency starting apparatus, and a starting current is also small; the provided method can effectively reduce a harmonic current when a variable frequency starting apparatus starts a power load, the phenomenon that two power sources supply power on a direct-current side of the variable frequency starting apparatus at the same time is avoided, thereby improving the stability and the economy of a micro grid.

Abstract: The invention relates to branched polymers which find use in gene therapy applications as nucleic acid transfection agents. In particular, the invention provides biodegradable, hyperbranched polymers which can be used in gene delivery and which provide improved transfection efficiencies which at the same time are safe and non-toxic.

Abstract: The present application relates to a photodetector based on interband transition in quantum wells. The photodetector may include a first semiconductor layer having a first conduction type; a second semiconductor layer having a second conduction type different from the first conduction type; and a photon absorption layer arranged between the first semiconductor layer and the second semiconductor layer, the photon absorption layer including at least one quantum well layer and barrier layers arranged on both sides of each quantum well layer. The present application utilizes the modulating effect of a semiconductor PN junction on a photoelectric conversion process associated with quantum wells to significantly increase a current output of the photodetector based on the quantum well material.

Abstract: A computer-implemented method for parallel content-defined data chunking may include (1) identifying a data stream to be chunked, (2) splitting the data stream into a plurality of data sub-streams by alternatingly dividing consecutive bytes of the data stream among the plurality of data sub-streams, and (3) chunking, in parallel, each data sub-stream within the plurality of data sub-streams into a plurality of data segments using a content-defined chunking algorithm. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: A system for staring a large-scale power load in a micro grid comprises a PCC grid connection switch, a micro grid alternating-current bus, an active power filter (APF), an energy storage inverter, an energy storage battery, a current-limiting resistor R, contactors K1-K3, a time relay KT, a power supply relay board, a micro grid maser control system, a frequency converter rectifying circuit, a frequency converter filter circuit, and a frequency converter inverter circuit. There are the advantages: an output torque of a power load can be effectively improved by using a variable frequency starting apparatus, and a starting current is also small; the provided method can effectively reduce a harmonic current when a variable frequency starting apparatus starts a power load, the phenomenon that two power sources supply power on a direct-current side of the variable frequency starting apparatus at the same time is avoided, thereby improving the stability and the economy of a micro grid.

Abstract: A hyperbranched copolymer comprising PEG-based monomers is described wherein the hyperbranched copolymer comprises a double bond content in the range 5 mol % to 50 mol %. RAFT (Reverse Addition-Fragmentation chain Transfer) polymerisation is used to synthesise the PEG-based hyperbranched copolymer described herein. The hyperbranched copolymer can be used for the preparation of antibacterial hydrogels.

Abstract: A polymer for transfecting a nucleic acid into a cell, the polymer comprising a plurality of polymeric branches, wherein at least one branch comprises at least one disulfide group and at least one vinyl group, which may an unsubstituted vinyl or a functionalized vinyl group.

Abstract: The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of surface-engineering surfactant which is one or more polymer that displays a lower critical solution temperature, in aqueous media, that is between 10 to 90° C., this polymer being the polymerization product of one or more monomer selected from polymerisable alkyleneglycol acrylate monomers and polymerisable alkyleneglycol methacrylate monomers. The polymer particles can be used in controlled release applications, such as flavour release applications, fragrance release applications and biomedical applications. The invention also provides a cell support matrix comprising the polymer particles.

Abstract: A system and method for improving performance within a storage system employing deduplication techniques using address manipulation are disclosed. A data segment within a storage object is identified from among a number of data segments within a storage object. The data segment represents data stored in a storage device. Some or all of the data represented by the data segment is stored in a data block that is associated with the data segment. The storage object is then compacted. Compaction includes reordering data segments, including the identified data segment, by performing address manipulation on a data block address of the data block (e.g., an address of the data block within the storage device). The reordering of the data segments changes the order of the data segments within the storage object.

Abstract: The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of surface-engineering surfactant which is one or more polymer that displays a lower critical solution temperature, in aqueous media, that is between 10 to 90° C., this polymer being the polymerisation product of one or more monomer selected from polymerisable alkyleneglycol acrylate monomers and polymerisable alkyleneglycol methacrylate monomers. The polymer particles can be used in controlled release applications, such as flavour release applications, fragrance release applications and biomedical applications. The invention also provides a cell support matrix comprising the polymer particles.

Abstract: A method of manufacturing epitaxial material used for GaN based LED with low polarization effect, which includes steps of growing n-type InGaAlN layer composed of GaN buffer layer (2) and n-type GaN layer (3), low polarizing active layer composed of InGaAlN multi-quantum well structure polarized regulating and controlling layer (4) and InGaAlN multi-quantum well structure light emitting layer (5) and p-type InGaAlN layer (6) on sapphire or SiC substrate (1) in turn. The method adds InGaAlN multi-quantum well structure polarized regulating and controlling layer, thus reduces polarization effect of quantum well active region.

Abstract: A method of manufacturing epitaxial material used for GaN based LED with low polarization effect, which includes steps of growing n-type InGaAlN layer composed of GaN buffer layer (2) and n-type GaN layer (3), low polarizing active layer composed of InGaAlN multi-quantum well structure polarized regulating and controlling layer (4) and InGaAlN multi-quantum well structure light emitting layer (5) and p-type InGaAlN layer (6) on sapphire or SiC substrate (1) in turn. The method adds InGaAlN multi-quantum well structure polarized regulating and controlling layer, thus reduces polarization effect of quantum well active region.