Abstract: A resource allocation method and apparatus of a multi-relay orthogonal frequency division multiplexing system are disclosed. The resource allocation method of a multi-relay orthogonal frequency division multiplexing system includes: obtaining actual channel information; obtaining resource allocation parameters according to a mathematical optimization problem based on the actual channel information, where the resource allocation parameters include at least two of subcarrier power allocation, relay selection and subcarrier pairing, and the mathematical optimization problem is a mathematical optimization problem set for the subcarrier power allocation, relay selection and subcarrier pairing by using an end-to-end transmission rate optimization principle and based on channel information; and transmitting a signal according to the resource allocation parameters. The foregoing technical solutions optimize system performance.

Abstract: A biodegradable polymer composition comprising: (a) a poly(phosphoester) biodegradable polymer and (b) at least one antineoplastic agent in an amount effective to inhibit the growth of a solid tumor, which is suitable for intratumoral administration to treat a mammal having a solid tumor.

Abstract: The present invension relates to compositions of a biocompatible polymer and a antineoplastic agent for treating central nervous system neoplasms, and methods of using and making the same. In certain embodiments, the polymer contains phosphorous linkages. In other embodiments, the antineoplastic agent is an antineoplastic taxane. In still other embodiments, the subject methods of treatment use electromagnetic radiation.

Abstract: Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I: wherein: each of R and R′ is independently straight or branched alkylene, either unsubstituted or substituted with one or more non-interfering substituents; L is a divalent cycloaliphatic group; R″ is selected from the group consisting of H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; and n is 5 to 1,000, wherein said biodegradable polymer is biocompatible before and upon biodegradation. In one embodiment, one or more of R, R′ or R″ is a biologically active substance. Amorphous compositions containing a biologically active substance, in addition to the polymer, and methods for controllably releasing biologically active substances using the compositions, are also described.

Abstract: Biodegradable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described, wherein the polymer compositions provide extended release of the antineoplastic agent into the peritoneum of the subject. The subject compositions can increase the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradable polymer. Solid articles and methods for treating ovarian cancer are also described.

Abstract: Biodegradable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described, wherein the polymer compositions provide extended release of the antineoplastic agent into the peritoneum of the subject. The subject compositions can increase the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradable polymer. Solid articles and methods for treating ovarian cancer are also described.

Abstract: A biodegradable polymer composition comprising:

Abstract: Biodegradable terephthalate polymers are described comprising the recurring monomeric units shown in formula I: wherein R is a divalent organic moiety; R′ is an aliphatic, aromatic or heterocyclic residue; x is ≧1; and n is 0-5,000, wherein the biodegradable polymer is biocompatible before and upon biodegradation. Processes for preparing the polymers, compositions containing the polymers and biologically active substances, articles useful for implantation or injection into the body fabricated from the compositions, and methods for controllably releasing biologically active substances using the polymers, are also described.

Abstract: Biodegradable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described, wherein the polymer compositions provide extended release of the antineoplastic agent into the peritoneum of the subject. The subject compositions can increase the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradable polymer. Solid articles and methods for treating ovarian cancer are also described.

Abstract: The present invention relates to compositions of a biocompatible polymer and an antineoplastic agent, and methods of using and making the same, for the treatment of head and neck cancers. In certain embodiments, the polymer contains phosphorous linkages. In other embodiments, the antineoplastic agent is an antineoplastic taxane.

Abstract: The present invention relates to compositions of a biocompatible polymer and an antineoplastic agent, and methods of using and making the same, for the treatment of prostate cancers. In certain embodiments, the polymer contains phosphorous linkages.

Abstract: The present invention relates in part to compositions comprising salts of an analgesic agent and an oil, and methods of using and making the same. In certain embodiments, the compositions may be used as part of a treatment regimen to alleviate pain.

Abstract: A biodegradable polymer composition comprising: (a) a poly(phosphoester) biodegradable polymer and (b) at least one antineoplastic agent in an amount effective to inhibit the growth of a solid tumor, which is suitable for intratumoral administration to treat a mammal having a solid tumor.

Abstract: The present invention relates to compositions comprising a biocompatible polymer with phosphorous linkages and a radiosensitizer, and methods of making and using the same.

Abstract: A medical device is described comprising a biodegradable terephthalate copolymer comprising the recurring monomeric units shown in formula I: wherein R is a divalent organic moiety; R′ is an aliphatic, aromatic or heterocyclic residue; x is ≧1; and n is 3-7, 500, where the biodegradable polymer is sufficiently pure to be biocompatible and is capable of forming biocompatible residues upon biodegradation. Compositions containing the copolymers and biologically active substances, articles useful for implantation or injection into the body fabricated from the compositions, and methods for controllably releasing biologically active substances using the copolymers, are also described.

Abstract: Biodegradeable polymer compositions suitable for intraperitoneal administration to treat a mammalian subject having ovarian cancer are described, wherein the polymer compositions provide extended release of the antineoplastic agent into the peritoneum of the subject. The subject compositions can increase the median survival rate from the cancer by at least about 10%, as compared with the median survival rate obtained by administration of a composition comprising the same dosage of the antineoplastic agent without the biodegradeable polymer. Solid articles and methods for treating ovarian cancer are also described.

Abstract: The present invention relates to compositions of a biocompatible polymer and an antineoplastic taxane, and methods of using and making the same, for the treatment of malignant effusions. In certain embodiments, the polymer contains phosphorous linkages.

Abstract: Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I: 1

Abstract: Biodegradable terephthalate polymers are described comprising the recurring monomeric units shown in formula I: 1

Abstract: Biodegradable, flowable or flexible polymer compositions are described comprising a polymer having the recurring monomeric units shown in formula I: wherein: each of R and R′ is independently straight or branched alkylene, either unsubstituted or substituted with one or more non-interfering substituents; L is a divalent cycloaliphatic group; R″ is selected from the group consisting of H, alkyl, alkoxy, aryl, aryloxy, heterocyclic or heterocycloxy; and n is 5 to 1,000, wherein said biodegradable polymer is biocompatible before and upon biodegradation. In one embodiment, one or more of R, R′ or R″ is a biologically active substance. Amorphous compositions containing a biologically active substance, in addition to the polymer, and methods for controllably releasing biologically active substances using the compositions, are also described.