Patents by Inventor Wen-Bin Yang

Wen-Bin Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230184751
    Abstract: The present invention relates to a system and method for carbohydrate analysis in a flow chemistry manner. The present invention at least features continuous reactions of glycan hydrolysis in combination with saccharide labeling which is helpful to improve the existing approaches in glycan structural analysis.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 15, 2023
    Applicant: ACADEMIA SINICA
    Inventor: Wen-Bin YANG
  • Patent number: 11133207
    Abstract: A method for forming a film is provided. The method includes sequentially placing a first wafer, a second wafer, and a third wafer in a chamber. The first wafer is separated from the second wafer by a first distance, the second wafer is separated from the third wafer by a second distance, and the first distance is smaller than the second distance. At least one process gas is introduced sequentially passing through the first wafer, the second wafer and the third wafer in the chamber.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: September 28, 2021
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Wen-Bin Yang, Feng-Yu Chen, Jian-Lun Lo
  • Publication number: 20200075372
    Abstract: A wafer boat includes at least one support member, at least one set of at least one first fixture member, at least one set of at least one second fixture member, and at least one set of at least one third fixture member. The support member extends in a direction. The set of the first fixture member, the set of the second fixture member, and the set of the third fixture member are supported by the support member and sequentially arranged in the direction. The set of the first fixture member is separated from the set of the second fixture member by a first pitch, and the set of the second fixture member is separated from the set of the third fixture member by a second pitch, in which the first pitch is smaller than the second pitch.
    Type: Application
    Filed: May 22, 2019
    Publication date: March 5, 2020
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventors: Wen-Bin YANG, Feng-Yu CHEN, Jian-Lun LO
  • Publication number: 20170299530
    Abstract: Provided is a method for quantitating a saccharide in a liquid sample. The method comprises incubating the liquid sample with 2,3-naphthalenediamine in the presence of iodine to allow a naphthimidazole group to be linked to the saccharide to obtain a first mixture; obtaining an 1H-NMR spectrum of the first mixture; and comparing, in said 1H-NMR spectrum, the intensity or integral of a proton signal corresponding to the saccharide to the intensity or integral of a proton signal corresponding to an internal standard present in the first mixture.
    Type: Application
    Filed: July 3, 2017
    Publication date: October 19, 2017
    Applicant: ACADEMIA SINICA
    Inventor: Wen-Bin YANG
  • Patent number: 9086416
    Abstract: Novel method and reagents for generating reversibly tagged saccharides, aldehydes, carboxyl acids, or orthoacetates useful in analytical and diagnostic applications are disclosed. Saccharides are coupled at the reducing end to tagging moieties comprising a reagent selected from a ortho-diaminobenzoic (DAB)-peptide, an aldo-imidazole or N-methylated aldo-imidazole, or an ortho-phenyldiamine (OPD) or substituted OPD. The tagged saccharide further comprising detectable or functional groups coupled to the tagging moiety are provided. Kits and reagents for chromatography and mass spectrometry are disclosed.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: July 21, 2015
    Assignee: Academia Sinica
    Inventor: Wen-Bin Yang
  • Publication number: 20150168415
    Abstract: Provided is an isotope-labelled compound having a general formula IIa?, S-Y?-BIM, wherein S is a sugar moiety, Y? is an isotope-containing sensor moiety and BIM is a benzimidazole. The compound may be used as an agent for saccharide analysis by magnetic resonance spectroscopy (NMR). A new glycan sequencing method and a glycoprotein synthesis method by using these compounds are also provided.
    Type: Application
    Filed: December 12, 2014
    Publication date: June 18, 2015
    Inventor: Wen-Bin YANG
  • Patent number: 8906380
    Abstract: Methods are disclosed which are useful in increasing maturation of dendritic cells from CD14+ mononuclear cells, by contact with a composition comprising a fucose-containing glycoprotein fraction from Ganoderma lucidum. The extract can also be used for increasing production of a cytokine or a chemokine in a dendritic cell or CD19+ B cell. In addition, a fucose-containing glycoprotein fraction from Ganoderma lucidum can be administered to a subject identified as needing increased immunoglobulin, cytokine, or chemokine production.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: December 9, 2014
    Assignee: Academia Sinica
    Inventors: Alice Yu, John Yu, Kuo-I Lin, Wen-Bin Yang, Chi-Huey Wong
  • Patent number: 8486914
    Abstract: Compositions comprising Hirsutella sinensis mycelia extracts and chromatographically separated polysaccharide-enriched fractions thereof are provided. Methods for extracting Hirsutella sinensis mycelia are provided. Compositions for methods for their use in amelioration, prevention and treatment of sepsis, acute endotoxemia and inflammatory responses are disclosed.
    Type: Grant
    Filed: March 30, 2010
    Date of Patent: July 16, 2013
    Assignee: Academia Sinica
    Inventors: Chi-Huey Wong, Alice L. Yu, Wen-Bin Yang, Eugene Fan, Hsien-Yeh Hsu, Peishan Lee, Tseng-Rong Tu, Chin-Chung Hung
  • Publication number: 20130102049
    Abstract: Novel method and reagents for generating reversibly tagged saccharides, aldehydes, carboxyl acids, or orthoacetates useful in analytical and diagnostic applications are disclosed. Saccharides are coupled at the reducing end to tagging moieties comprising a reagent selected from a ortho-diaminobenzoic(DAB)-peptide, an aldo-imidazole or N-methylated aldo-imidazole, or an ortho-phenyldiamine (OPD) or substituted OPD. The tagged saccharide further comprising detectable or functional groups coupled to the tagging moiety are provided. Kits and reagents for chromatography and mass spectrometry are disclosed.
    Type: Application
    Filed: July 12, 2012
    Publication date: April 25, 2013
    Applicant: ACADEMIA SINICA
    Inventor: Wen-Bin YANG
  • Patent number: 8354127
    Abstract: Compositions and methods are disclosed relating to use of fractions, polysaccharides, and oligosaccharides of Dendrobium huoshanense. The fractions, polysaccharides, and oligosaccharides are able to effect an increase in beneficial cytokines and chemokines.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: January 15, 2013
    Assignee: Academia Sinica
    Inventors: Chi-Huey Wong, Wen-Bin Yang, Ting-Jen Cheng, Yves Shang-Yi Hsieh, Cheng Chien, Chih-Chien Lin, Hao-Yu Wen, Jim-Min Fang
  • Publication number: 20120260971
    Abstract: A method of fabricating a III-V solar cell package includes providing a solar cell having a first side and an opposite second side, forming a first insulating layer on the first side of the solar cell, forming a second insulating layer on the second side of the solar cell, forming a light-transmitting layer on the first insulating layer, forming a protection layer on the second insulating layer, and laminating the light-transmitting layer and the protection layer so as to attach the first insulating layer to the light-transmitting layer and the solar cell and to attach the second insulating layer to the protection layer and the solar cell, thereby forming a flexible solar cell package since the insulating layers, the light-transmitting layer and the protection layer are all flexible.
    Type: Application
    Filed: April 15, 2011
    Publication date: October 18, 2012
    Applicant: EVERPHOTON ENERGY CORP.
    Inventors: Yee-Lee Chen, Yu-Pei Huang, Wen-Bin Yang, Pei-Hsuan Wu
  • Publication number: 20120147477
    Abstract: A lens includes a glass substrate, and a silicone layer adhered to the glass substrate and having a pattern formed on an outer surface thereof. Since the light-transmissive silicone layer is directly adhered to the glass substrate, without the use of an adhesive layer, the fabrication cost and thickness of the lens are reduced, and the objective of thinning the lens is achieved.
    Type: Application
    Filed: February 23, 2011
    Publication date: June 14, 2012
    Applicant: EVERPHOTON ENERGY CORP.
    Inventors: Yee-Lee Chen, Yu-Pei Huang, Wen-Bin Yang
  • Patent number: 8071105
    Abstract: The present disclosure relates to the discovery of methods of isolating subfractions of an F3 Reishi extract, and of administration of these novel isolates to eukaryotic cells in order to induce certain immumodulatory, hematopoeitic and tumor-inhibiting phenotypic changes in those eukaryotic cells, mediated through particular toll-like receptor (TLR) and other transmembrane receptors. F3 subfractions F301 and F331 have demonstrated that F331 is capable of activating at least TLR-2 while F301 is capable of activating at least TLR-2, TLR-4, and TLR-5.
    Type: Grant
    Filed: October 2, 2008
    Date of Patent: December 6, 2011
    Assignee: Academia Sinica
    Inventors: Shu-Mei Liang, Yen-Po Chen, Wen-Bin Yang, Chi-Huey Wong
  • Publication number: 20110028428
    Abstract: Compositions comprising Hirsutella sinensis mycelia extracts and chromatographically separated polysaccharide-enriched fractions thereof are provided. Methods for extracting Hirsutella sinensis mycelia are provided. Compositions for methods for their use in amelioration, prevention and treatment of sepsis, acute endotoxemia and inflammatory responses are disclosed.
    Type: Application
    Filed: March 30, 2010
    Publication date: February 3, 2011
    Applicant: WYNTEK CORP
    Inventors: Chi-Huey Wong, Alice L. Yu, Wen-Bin Yang, Eugene Fan, Hsien-Yeh Hsu, Peishan Lee, Tseng-Rong Tu, Chin-Chung Hung
  • Publication number: 20090280062
    Abstract: A composition of acetic acid and a composition of acetic acid and RF3 effecting expression of DAF-16 in C. elegans, wherein the at least acetic acid and the RF3 polysaccharide is effective to increase the life-span of C. elegans or humans. A method of regulating DAF-16 expression, comprising: administering a composition comprising at least acetic acid and RF3 polysaccharide; providing the composition to at least one receptor on a surface of a cell; causing an increase in expression of DAF-16. A method for screening a series of compounds or constituents parts of compounds including some antioxidant vitamins, traditional herb medicines, and vinegars using C. elegans as a live organism model to examine to determine if they have an impact the lifespan of C. elegans and the underlying mechanism(s) thereof.
    Type: Application
    Filed: April 16, 2009
    Publication date: November 12, 2009
    Inventors: Chi-Huey Wong, Ming-Hong Chuang, Wen-Bin Yang, Shyh-Horng Chiou
  • Publication number: 20090270344
    Abstract: Compositions and methods are disclosed relating to use of fractions, polysaccharides, and oligosaccharides of Dendrobium huoshanense. The fractions, polysaccharides, and oligosaccharides are able to effect an increase in beneficial cytokines and chemokines.
    Type: Application
    Filed: February 12, 2009
    Publication date: October 29, 2009
    Inventors: Chi-Huey Wong, Wen-Bin Yang, Ting-Jen Cheng, Yves Shang-Yi Hsieh, Cheng Chien, Chih-Chien Lin, Hao-Yu Wen, Jim-Min Fang
  • Publication number: 20090263897
    Abstract: The present disclosure relates to the discovery of methods of isolating subfractions of an F3 Reishi extract, and of administration of these novel isolates to eukaryotic cells in order to induce certain immumodulatory, hematopoeitic and tumor-inhibiting phenotypic changes in those eukaryotic cells, mediated through particular toll-like receptor (TLR) and other transmembrane receptors. F3 subfractions F301 and F331 have demonstrated that F331 is capable of activating at least TLR-2 while F301 is capable of activating at least TLR-2, TLR-4, and TLR-5.
    Type: Application
    Filed: October 2, 2008
    Publication date: October 22, 2009
    Inventors: Shu-Mei Liang, Yen-Po Chen, Wen-Bin Yang, Chi-Huey Wong
  • Publication number: 20070231339
    Abstract: Methods are disclosed which are useful in increasing maturation of dendritic cells from CD14+ mononuclear cells, by contact with a composition comprising a fucose-containing glycoprotein fraction from Ganoderma lucidum. The extract can also be used for increasing production of a cytokine or a chemokine in a dendritic cell or CD19+ B cell. In addition, a fucose-containing glycoprotein fraction from Ganoderma lucidum can be administered to a subject identified as needing increased immunoglobulin, cytokine, or chemokine production.
    Type: Application
    Filed: October 13, 2006
    Publication date: October 4, 2007
    Applicant: ACADEMIA SINICA
    Inventors: Alice Yu, John Yu, Kuo-I Lin, Wen-Bin Yang, Chi-Huey Wong
  • Patent number: 7078520
    Abstract: This invention relates to a method of preparing a first alicyclic compound having a vinyl group on one alkyl ring carbon and an alkoxy, cycloalkoxy, heterocycloalkyoxy, aryloxy, or heteroaryloxy group on the same ring carbon; the method comprising reacting an aliphatic alcohol or an aromatic alcohol with a second alicyclic compound having an exo cyclic carbon-carbon double bond, wherein the non-ring olefinic carbon is substituted with a hydroxymethyl, thiomethyl, alkoxymethyl, aryloxymethyl, acyloxymethyl, alkylsulfonyloxymethyl, arylsulfonyloxymethyl, alkylsulfonylmethyl, arylsulfonylmethyl, halomethyl, or silyloxymethyl group.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: July 18, 2006
    Assignee: Academia Sinica
    Inventors: Chun-Hung Lin, Wen-Bin Yang, Hui-Chang Lin
  • Publication number: 20040199029
    Abstract: This invention relates to a method of preparing a first alicyclic compound having a vinyl group on one alkyl ring carbon and an alkoxy, cycloalkoxy, heterocycloalkyoxy, aryloxy, or heteroaryloxy group on the same ring carbon; the method comprising reacting an aliphatic alcohol or an aromatic alcohol with a second alicyclic compound having an exo cyclic carbon-carbon double bond, wherein the non-ring olefinic carbon is substituted with a hydroxymethyl, thiomethyl, alkoxymethyl, aryloxymethyl, acyloxymethyl, alkylsulfonyloxymethyl, arylsulfonyloxymethyl, alkylsulfonylmethyl, arylsulfonylmethyl, halomethyl, or silyloxymethyl group.
    Type: Application
    Filed: April 4, 2003
    Publication date: October 7, 2004
    Inventors: Chun-Hung Lin, Wen-Bin Yang, Hui-Chang Lin