Patents by Inventor Wenbing Yao
Wenbing Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12226476Abstract: A helper epitope peptide is obtained by means of replacing one or two amino acid residues in the helper T cell epitope PADRE with 4-nitrophenylalanine. The helper epitope peptide is effective for enhancing the immunogenicity of an antigen or antigenic epitope or for preparing or constructing a vaccine, and a fusion antigen formed by connecting the helper epitope peptide to an antigen or an antigenic epitope.Type: GrantFiled: April 19, 2019Date of Patent: February 18, 2025Assignee: CHINA PHARMACEUTICAL UNIVERSITYInventors: Wenbing Yao, Hong Tian, Yi Xu, Yu He, Xiangdong Gao
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Publication number: 20210162041Abstract: A helper epitope peptide is obtained by means of replacing one or two amino acid residues in the helper T cell epitope PADRE with 4-nitrophenylalanine. The helper epitope peptide is effective for enhancing the immunogenicity of an antigen or antigenic epitope or for preparing or constructing a vaccine, and a fusion antigen formed by connecting the helper epitope peptide to an antigen or an antigenic epitope.Type: ApplicationFiled: April 19, 2019Publication date: June 3, 2021Inventors: Wenbing YAO, Hong TIAN, Yi XU, Yu HE, Xiangdong GAO
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Patent number: 10926998Abstract: A pure bamboo fiber mattress and a manufacturing method thereof are disclosed. The manufacturing method includes the following steps: trimming and cleaning bamboo; sawing; splitting; slicing the bamboo strips; knitting; softening; directional fiber opening; dry cleaning, drying and removing dust; stacking; sewing and packing. The pure bamboo fiber mattress includes a surface layer, a transition layer, a core layer, another transition layer and another surface layer that are arranged in sequence from top to bottom. The surface layer includes 3-5 layers of first bamboo mesh fabric laid one on top of another. The transition layer includes 3-8 layers of second bamboo mesh fabric laid one on top of another. The core layer includes 3-8 layers of third bamboo mesh fabric laid one on top of another. The first bamboo mesh fabric, the second bamboo mesh fabric and the third bamboo mesh fabric are made of bamboo fibers.Type: GrantFiled: November 30, 2018Date of Patent: February 23, 2021Assignees: JIYANG COLLEGE OF ZHEJIANG A&F UNIVERSITY, CHONGQING SHENGFANG NEW MATERIAL TECH CO., LTD.Inventors: Wenbing Yao, Yiting Zhang
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Patent number: 10822724Abstract: An apparatus for delaminating a bamboo into fibers includes a machine frame, a machine seat arranged in a middle of the machine, a machine cover matching with the machine seat, a push plate, a power source, and an elastic member. The machine seat includes multiple grooves formed in a top to respectively receive therein bamboo pieces. The machine cover includes multiple ribs formed on a bottom thereof. The machine cover is slidable relative to the machine seat to have the ribs of the machine cover respectively receivable in and engageable with the grooves of the machine seat so as to sandwich bamboo pieces therebetween. A push plate is driven by the power source to selectively move relative to the machine seat and has a bent end portion that bends and pushes portions of the bamboo pieces to slide on the top of the machine cover.Type: GrantFiled: November 28, 2016Date of Patent: November 3, 2020Assignee: JIYANG COLLEGE OF ZHEJIANG A&F UNIVERSITYInventors: Wenbing Yao, Chao Zhou, Maoyang Lin, Yao Yao
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Publication number: 20200172390Abstract: A pure bamboo fiber mattress and a manufacturing method thereof are disclosed. The manufacturing method includes the following steps: trimming and cleaning bamboo; sawing; splitting; slicing the bamboo strips; knitting; softening; directional fiber opening; dry cleaning, drying and removing dust; stacking; sewing and packing. The pure bamboo fiber mattress includes a surface layer, a transition layer, a core layer, another transition layer and another surface layer that are arranged in sequence from top to bottom. The surface layer includes 3-5 layers of first bamboo mesh fabric laid one on top of another. The transition layer includes 3-8 layers of second bamboo mesh fabric laid one on top of another. The core layer includes 3-8 layers of third bamboo mesh fabric laid one on top of another. The first bamboo mesh fabric, the second bamboo mesh fabric and the third bamboo mesh fabric are made of bamboo fibers.Type: ApplicationFiled: November 30, 2018Publication date: June 4, 2020Inventors: Wenbing Yao, Yiting Zhang
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Patent number: 10640887Abstract: A continuous processing device for forming bamboo fiber includes a machine rail, a cart guide rail, a cart, and a clamp for clamping a bamboo strip. The cart and the clamp are connected through a connecting plate. The machine rail is formed with a slot along a path of the machine rail. The machine rail includes a head linear rail section, a conical spiral rail section and a tail linear rail section arranged in sequence. The cart guide rail includes a head linear guide rail section, a conical spiral guide rail section and a tail linear guide rail section arranged in sequence. A continuous processing method for forming bamboo fiber using the continuous processing device is disclosed.Type: GrantFiled: November 28, 2016Date of Patent: May 5, 2020Assignee: JIYANG COLLEGE OF ZHEJIANG A&F UNIVERSITYInventors: Wenbing Yao, Chao Zhou
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Publication number: 20190054649Abstract: A manufacturing apparatus for delaminating a bamboo into fiber and a method thereof are disclosed. The manufacturing apparatus includes a machine frame, a machine seat, a machine cover matched with the machine seat, a machine cover rail, a push plate, a push rail, at least one power source for sliding the push plate, and at least one elastic member. The manufacturing apparatus has a relatively simple structure and is easy for operation, use, and promotion. The manufacturing method using the manufacturing apparatus is simple in production process, high in efficiency, and free from pollution. The obtained bamboo fiber has good elasticity, good toughness, fine fiber fineness and uniformity, that is, the present invention can quickly and efficiently produce high-quality bamboo fiber, greatly saving the production time of bamboo fiber, improving the production efficiency, and reducing the production cost.Type: ApplicationFiled: November 28, 2016Publication date: February 21, 2019Inventors: Wenbing YAO, Chao ZHOU, Maoyang LIN, Yao YAO
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Publication number: 20190055670Abstract: A continuous processing device for forming bamboo fiber includes a machine rail, a cart guide rail, a cart, and a clamp for clamping a bamboo strip. The cart and the clamp are connected through a connecting plate. The machine rail is formed with a slot along a path of the machine rail. The machine rail includes ahead linear rail section, a conical spiral rail section and a tail linear rail section arranged in sequence. The cart guide rail includes ahead linear guide rail section, a conical spiral guide rail section and a tail linear guide rail section arranged in sequence. A continuous processing method for forming bamboo fiber using the continuous processing device is disclosed. The present invention can quickly and efficiently produce a large quantity of high-quality bamboo fiber, greatly saving the production time of bamboo fiber, improving the production efficiency, and reducing the production cost.Type: ApplicationFiled: November 28, 2016Publication date: February 21, 2019Inventors: Wenbing YAO, Chao ZHOU
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Patent number: 8802824Abstract: Provided is a kind of modified recombinant human endostatin that has the structure of CH3O—(CH2CH2O)m—CH2CH2CH2—N?H-Endostar, wherein the average molecular weight of CH3O—(CH2CH2O)m—CH2CH2CH2— is 20-40 kD. The modified recombinant human endostatin enhances the stability in vivo, improves blood drug concentration, prolongs half-life, markedly increases the activity of inhibiting the endothelial cells proliferation, thus reduces drug dosage and decreases administration frequency. Its application for preparing anti-tumor pharmaceutical compositions is also provided.Type: GrantFiled: September 4, 2008Date of Patent: August 12, 2014Assignees: Jiangsu Simcere Pharmaceutical R&D Co., Ltd., Shandong Xiansheng Maidejin Biological Pharmaceutical Co., Ltd.Inventors: Wenbing Yao, Hong Tian, Xiangyang Xu, Hairui Li, Yue Dong, Xiangdong Gao
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Publication number: 20100210822Abstract: Provided is a kind of modified recombinant human endostatin that has the structure of CH3O—(CH2CH2O)m—CH2CH2CH2—N?H-Endostar, wherein the average molecular weight of CH3O—(CH2CH2O)m—CH2CH2CH2— is 20-40 kD. The modified recombinant human endostatin enhances the stability in vivo, improves blood drug concentration, prolongs half-life, markedly increases the activity of inhibiting the endothelial cells proliferation, thus reduces drug dosage and decreases administration frequency. Its application for preparing anti-tumor pharmaceutical compositions is also provided.Type: ApplicationFiled: September 4, 2008Publication date: August 19, 2010Applicants: JIANGSU SIMCERE PHARMACEUTICAL R&D CO., LTD., CHINA PHARMACEUTICAL UNIVERSITY, Shandong Xiansheng Maidejin Biologial Pharmaceutia l Co. LtdInventors: Wenbing Yao, Hong Tian, Xiangyang Xu, Hairui Li, Yue Dong, Xiangdong Gao