Abstract: The present invention relates to novel small molecule activators of Sirt6, for example, compounds of the general Formula (I), their methods and use for the treatment of various human diseases such as cancer, inflammatory diseases, neurodegenerative diseases, and infectious diseases:

Abstract: An electronic equipment, a user equipment, a wireless communication method, and a storage medium, the electronic equipment comprising a processing circuit and being configured to: receive from a user equipment a random access request message that is expected to access a satellite equipment; and in response to the random access request message, send to the user equipment the advance in timing between the user equipment and the satellite equipment to be accessed. By using said electronic equipment, user equipment, wireless communication method, and storage medium, a user equipment in a satellite communication system may more quickly and efficiently acquire control information relating to uplink transmission.

Abstract: A method for estimating channel parameters includes: sending a paging signal for identifying the tag device; sending training sequence information, receiving first training sequence feedback information during a non-working period of the tag device, receiving, during a working period of the tag device, second training sequence feedback information modulated by the tag device, and estimating the channel parameters of the tag device according to the training sequence feedback information and the second training sequence feedback information. The tag device having at least one antenna of the present disclosure can modulate carrier signals to transmit information, has advantages such as a fast transmission rate, a large amount of transmission data and a strong anti-interference capability, and can adapt to different application scenarios.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining breakpoints in a media item. Methods can include determining a candidate set of breakpoints within a media item. A machine learning model is used to generate a score for each particular candidate breakpoint in the set of candidate breakpoints based on presentation features of the media item. A subset of candidate breakpoints is selected from the set of candidate breakpoints based on the score. A final set of breakpoints is selected from the subset of candidate breakpoints based on a combination of the score for each particular candidate breakpoint and a location of the particular candidate breakpoint relative to a different candidate breakpoint. The final set of breakpoints is stored in a database and during playback of the media item, a digital component is presented when the media item reaches a stored breakpoint.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for automatically determining parameter values that control or affect provision of content by a content platform. In one aspect, evaluation points are identified for a parameter. Each evaluation point includes an evaluated parameter value of the parameter and a metric value of a metric corresponding to the provision of digital components by the content platform. A first model is generated using the set of evaluation points. A second model is generated based on the first model and an acquisition function that is based on mean values and confidence intervals of the first model and a configurable exploration weight that controls a priority of exploration for evaluating the parameter. A next parameter value to evaluate is determined from the second model and the content platform is configured to use the next parameter value to provide digital components.

Abstract: Disclosed in the present application are an apparatus and method in a wireless communication system, and a computer readable storage medium. The apparatus comprises a processing circuit. The processing circuit is configured to determine one or more height thresholds for a user equipment according to at least one of base station-related information, cell-related information and user equipment-related information. According to at least one aspect of embodiments of the present disclosure, a proper height threshold is set for a communication scenario of an unmanned aerial vehicle, which helps to resolve and alleviate various problems that may exist in the communication scenario of the unmanned aerial vehicle.

Abstract: Memory device, memory system and formation method are provided. The method includes forming a sacrificial layer over a dielectric-pair stack, the sacrificial layer containing a top selective gate (TSG) cut structure over the dielectric-pair stack; forming a channel plug structure including a lower plug portion in the dielectric-pair stack and an upper plug portion through the sacrificial layer; forming a barrier layer at least enveloping the upper plug portion of the channel plug structure after a removal of the sacrificial layer; and forming a semiconductor layer over the dielectric-pair stack to embed the TSG cut structure, the barrier layer, and the upper plug portion of the channel plug structure.

Abstract: Memory device, memory system, and formation method are provided. The formation method includes providing a dielectric-pair stack containing a channel layer extending there-through, and forming a sacrificial layer in the dielectric-pair stack and in contact with the channel layer; forming a semiconductor layer over the dielectric-pair stack, the semiconductor layer containing a top selective gate (TSG) cut structure; forming a trench through the semiconductor layer to expose the sacrificial layer; forming a barrier layer on sidewalls of the semiconductor layer exposed by the trench; forming a recess by removing the sacrificial layer; and forming a channel plug structure in the trench and the recess.

Abstract: A method for estimating channel parameters includes: sending a paging signal for identifying the tag device; sending training sequence information, receiving first training sequence feedback information during a non-working period of the tag device, receiving, during a working period of the tag device, second training sequence feedback information modulated by the tag device, and estimating the channel parameters of the tag device according to the training sequence feedback information and the second training sequence feedback information. The tag device having at least one antenna of the present disclosure can modulate carrier signals to transmit information, has advantages such as a fast transmission rate, a large amount of transmission data and a strong anti-interference capability, and can adapt to different application scenarios.

Abstract: Three-dimensional (3D) memory devices and methods for forming the same are disclosed. In certain aspects, a 3D memory device includes a first semiconductor structure including alternating first dielectric layers and first conductive layers, an array common source (ACS) film over the first semiconductor structure, a second semiconductor structure over the ACS film, and a channel structure extending in the first semiconductor structure, the ACS film, and the second semiconductor structure in a first direction. The second semiconductor structure includes alternating second dielectric layers and second conductive layers. The channel structure is electrically connected to the ACS film.

Abstract: Semiconductor components, fabrication methods thereof and memory systems. A fabrication method includes performing trap repairing on a first wafer at a first temperature, the first wafer including memory cells; bonding the first wafer with a second wafer to form a semiconductor component, the second wafer including a device layer; and repairing the semiconductor component at a second temperature lower than the first temperature.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining watch time loss regions in media content items. In one aspect, features for a video are input into a trained model that is trained to output watch time loss regions. The trained model is trained using labels corresponding to known watch time loss regions in training videos and features of training videos that correspond to the known watch time loss regions. A watch time loss region defines a time window of a video during which a likelihood of a user stopping playback of the video is more than a threshold likelihood. In response to inputting the feature for the first video into the trained model, data regarding watch time loss regions for the video is obtained from the model and provided to an entity involved in providing the video to a user.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for automatically determining parameter values that control or affect provision of content by a content platform. In one aspect, evaluation points are identified for a parameter. Each evaluation point includes an evaluated parameter value of the parameter and a metric value of a metric corresponding to the provision of digital components by the content platform. A first model is generated using the set of evaluation points. A second model is generated based on the first model and an acquisition function that is based on mean values and confidence intervals of the first model and a configurable exploration weight that controls a priority of exploration for evaluating the parameter. A next parameter value to evaluate is determined from the second model and the content platform is configured to use the next parameter value to provide digital components.

Abstract: The present disclosure relates to an electronic apparatus, a wireless communication method and a computer-readable medium. The electronic apparatus for wireless communication according to one embodiment comprises a processing circuit. The processing circuit is configured to perform control to send or receive configuration information. The configuration information is related to configuration of a reference signal used in a discovery process of an integrated access backhaul (IAB) link node.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining watch time loss regions in media content items. In one aspect, features for a video are input into a trained model that is trained to output watch time loss regions. The trained model is trained using labels corresponding to known watch time loss regions in training videos and features of training videos that correspond to the known watch time loss regions. A watch time loss region defines a time window of a video during which a likelihood of a user stopping playback of the video is more than a threshold likelihood. In response to inputting the feature for the first video into the trained model, data regarding watch time loss regions for the video is obtained from the model and provided to an entity involved in providing the video to a user.

Abstract: The present disclosure relates to an electronic apparatus, a wireless communication method and a computer-readable medium. According to one embodiment, an electronic apparatus for wireless communication comprises: a processing circuit configured to: determine whether a first user equipment satisfies a condition for performing direct link communication with a second user equipment by using an unlicensed frequency band resource; and if the condition is satisfied, control the first user equipment to perform direct link communication with the second user equipment by using the unlicensed frequency band resource.

Abstract: Disclosed is a user equipment for satellite communication, comprising one or more processing circuits configured to execute the following operations: evaluating a transmission power requirement for a user equipment to communicate with a satellite; and assisting, via an auxiliary device, the user equipment in executing at least part of the communication with the satellite when the transmission power constraint of the user equipment fails to meet the transmission power requirement, wherein the processing circuits are further configured to acquire, via the satellite, a communication mode to be switched to, and the processing circuits transmit, to the satellite, a notification indicating that a current communication mode needs to be switched, with the notification comprising information indicating the need to switch to a communication mode that meets the transmission power requirement.

Abstract: Disclosed in the present invention are a wireless communication method and a wireless communication device. An electronic device in communication with a counterpart communication device comprises a processing circuit, the processing circuit being configured to: determine the state of a link between the electronic device and the counterpart communication device by means of measuring a link maintenance message transmitted by the counterpart communication device when a predetermined condition relative to the counterpart communication device is met, but not to transmit a feedback message for the link maintenance message, wherein the link maintenance message is used for confirming that the link is maintained between the electronic device and the counterpart communication device.

Abstract: The present disclosure relates to an electronic apparatus, a wireless communication method, and a computer readable storage medium. The electronic apparatus in an integrated access and backhaul (IAB) system according to the present disclosure comprises a processing circuit, and is configured to: configure, according to the electronic apparatus and a subcarrier interval of a link between sub-nodes of the electronic apparatus, a slot formatting cycle for the link, the slot formatting cycle comprising a pre-determined number of slots; and configure, for the link, a slot format of each slot in one slot format cycle. The electronic apparatus, the wireless communication method, and the computer readable storage medium of the present disclosure optimize slot format configuration in IAB systems.

Abstract: An apparatus and a method of a wireless communication system, and a computer-readable storage medium are disclosed. The apparatus comprises a processing circuit. The processing circuit is configured to configure, directly or indirectly on the basis of one or more height thresholds for user equipment and a current height of the user equipment, operation of the user equipment. According to at least one aspect of the embodiments of the disclosure, configuring, on the basis of a height threshold, operation of a user equipment optimizes communication performance in an unmanned aerial vehicle communication scenario.