Abstract: An audio control method, a control device, a driving circuit and a readable storage medium are provided. The audio control method according to some embodiments of the present disclosure is applicable to the display screen configured with M speakers, and the method includes: obtaining a sound image coordinate of a sound object relative to the display screen; determining N speakers from the M speakers as loudspeakers according to the sound image coordinate and position coordinates of the M speakers relative to the display screen; determining output gains of the N loudspeakers according to distances between the N loudspeakers and a viewer of the display screen and sound attenuation coefficients; and calculating output audio data of the sound object in the display screen according to audio data of the sound object and the output gains of the N loudspeakers, and controlling the M speakers to play the output audio data.

Abstract: Compositions of engineered extracellular vesicles for delivery of cargo to targeted tissues and cells are described herein. Also described herein are methods for making and using the extracellular vesicles described herein. Lastly, described herein are methods for treating a subject, the method comprising administering to a subject an extracellular vesicle as described herein.

Abstract: Compositions and methods for modified viral vectors which mitigate the immunogenicity of viral vectors, enabling multiple administrations of viral-based gene delivery viral vectors are described herein. The viral vectors advantageously possess low immunogenicity and comprise at least one immunosuppressive moiety. Also described herein are methods for introducing genetic material into a cell. Additionally, described herein are methods for preparing a modified viral vector. Lastly, described herein are methods for treating a subject, the method comprising administering to a subject a modified viral vector composition as described above.