Abstract: A sample signal amplification method using a terahertz band graphene absorber is provided. The method comprises: fabricating a graphene absorber through steps of metal evaporation, graphene transfer and the like; preparing sample solutions having different concentrations; dropwise adding a sample solution to the surface of the graphene absorber, and then drying in the air at room temperature; collecting terahertz time-domain signals of all sample points to be detected and reference sample points on the surface of the graphene absorber; and calculating absorption rates of all the sample points to be detected and the reference sample points according to the terahertz time-domain signals, and calculating the intensity change of an absorption peak according to the intensity value corresponding to the highest point of the absorption peak.

Abstract: A sample signal amplification method using a terahertz band graphene absorber is provided. The method comprises: fabricating a graphene absorber through steps of metal evaporation, graphene transfer and the like; preparing sample solutions having different concentrations; dropwise adding a sample solution to the surface of the graphene absorber, and then drying in the air at room temperature; collecting terahertz time-domain signals of all sample points to be detected and reference sample points on the surface of the graphene absorber; and calculating absorption rates of all the sample points to be detected and the reference sample points according to the terahertz time-domain signals, and calculating the intensity change of an absorption peak according to the intensity value corresponding to the highest point of the absorption peak.

Abstract: Implementations herein relates to a biological sample signal amplification method using terahertz metamaterials and gold nanoparticles. A plurality of biological sample solutions and a plurality of gold nanoparticles-labeled avidin solutions are dropped on surfaces of metamaterials and dried at room temperature. Terahertz time-domain signals of sample points and reference sample points on the surfaces of metamaterials are acquired, transmission or reflectance of the sample points and the reference sample points are calculated using terahertz time-domain signals, and the frequency shift of transmission or reflection peaks are calculated according to the lowest point of transmission or reflectance. The effect of local electric field enhancement of metamaterials is used for sample signal amplification, gold nanoparticles are used to change a distribution of electric fields, and a sample signal is further enhanced by gold nanoparticles modification.

Abstract: Implementations herein relates to a biological sample signal amplification method using terahertz metamaterials and gold nanoparticles. A plurality of biological sample solutions and a plurality of gold nanoparticles-labeled avidin solutions are dropped on surfaces of metamaterials and dried at room temperature. Terahertz time-domain signals of sample points and reference sample points on the surfaces of metamaterials are acquired, transmission or reflectance of the sample points and the reference sample points are calculated using terahertz time-domain signals, and the frequency shift of transmission or reflection peaks are calculated according to the lowest point of transmission or reflectance. The effect of local electric field enhancement of metamaterials is used for sample signal amplification, gold nanoparticles are used to change a distribution of electric fields, and a sample signal is further enhanced by gold nanoparticles modification.