Patents by Inventor Wendelin Frick

Wendelin Frick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
    Publication number: 20050267038
    Abstract: Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Application
    Filed: June 17, 2005
    Publication date: December 1, 2005
    Inventors: Heiner Glombik, Werner Krame, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schafer
  • Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20050267177
    Abstract: Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed. The compounds include those of formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds typically have lipid- and/or triglyceride-lowering properties and are suitable, for example, for the treatment of disorders of lipid metabolism, of type II diabetes, and of syndrome X.
    Type: Application
    Filed: April 4, 2005
    Publication date: December 1, 2005
    Inventors: Heiner Glombik, Eugen Falk, Wendelin Frick, Stefanie Keil, Hans-Ludwig Schafer, Lothar Schwink, Wolfgang Wendler
  • Method of treatment with combinations of statin and aryl-substituted propanolamine derivatives
    Patent number: 6897198
    Abstract: Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which the radicals have the abovementioned meanings, and their physiologically tolerated salts, physiologically functional derivates and processes for their preparation. The compounds are suitable as, for example, hypolipidemics.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: May 24, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Reinhard Kirsch, Heiner Glombik, Werner Kramer, Hans-Ludwig Schäfer
  • Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
    Patent number: 6884812
    Abstract: Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed. The compounds include those of formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds typically have lipid- and/or triglyceride-lowering properties and are suitable, for example, for the treatment of disorders of lipid metabolism, of type II diabetes, and of syndrome X.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: April 26, 2005
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Eugen Falk, Wendelin Frick, Stefanie Keil, Hans-Ludwig Schäfer, Lothar Schwink, Wolfgang Wendler
  • Nover diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use
    Publication number: 20050020563
    Abstract: The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
    Type: Application
    Filed: March 31, 2004
    Publication date: January 27, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Gerhard Jaehne, Wendelin Frick, Andreas Lindenschmidt, Stefanie Flohr, Hubert Heuer, Hans-Ludwig Schaefer, Werner Kramer, Eric Galia, Heiner Glombik
  • Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
    Publication number: 20050014704
    Abstract: Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof. The invention relates to substituted aromatic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and process for their preparation. The compounds are suitable for example as antidiabetics.
    Type: Application
    Filed: December 12, 2003
    Publication date: January 20, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Heiner Glombik, Werner Kramer, Hurbert Heuer, Harm Brummerhop, Oliver Plettenburg
  • Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines
    Publication number: 20050009863
    Abstract: Substituted 4-phenyltetrahydroisoquinolines of formula I, process for their preparation, their use as a medicament and medicaments containing them. The compounds of formula I can be used, among other uses, in the event of renal disorders such as acute or chronic renal failure, in the event of disorders of biliary function, in the event of respiratory disorders such as snoring or sleep apneas or in the event of stroke.
    Type: Application
    Filed: March 24, 2004
    Publication date: January 13, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Armin Hofmeister, Uwe Heinelt, Hans-Jochen Lang, Wendelin Frick, Markus Bleich, Klaus Wirth
  • Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
    Publication number: 20040259819
    Abstract: Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof.
    Type: Application
    Filed: December 12, 2003
    Publication date: December 23, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Heiner Glombik, Werner Kramer, Hubert Heuer, Harm Brummerhop, Oliver Plettenburg
  • Phosophoinositoglycan binding proteins
    Publication number: 20040229278
    Abstract: The invention refers to a protein from plasma membrane of adipocytes. The protein has specific binding affinity to phosphoinositoylglycans. It regulates glucose uptake by circumventing the insulin signaling cascade.
    Type: Application
    Filed: July 3, 2003
    Publication date: November 18, 2004
    Inventors: Guenter Mueller, Wendelin Frick, Stefan Petry, Rudolf Schneider, Matthias Urmann
  • Novel thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof
    Publication number: 20040138143
    Abstract: Novel thiophene glycoside derivatives of the formula I 1
    Type: Application
    Filed: July 11, 2003
    Publication date: July 15, 2004
    Inventors: Heiner Glombik, Wendelin Frick, Hubert Heuer, Werner Kramer, Harm Brummerhop, Oliver Plettenburg
  • Method for isolating an intestinal cholesterol binding protein
    Publication number: 20040126812
    Abstract: The invention describes a method for isolating an intestinal protein which is able to bind cholesterol and/or cholesterol uptake inhibitors. Methods of identifying inhibitors of cholesterol uptake and related pharmaceuticals and methods of treatment also are described.
    Type: Application
    Filed: August 6, 2003
    Publication date: July 1, 2004
    Inventors: Werner Kramer, Wendelin Frick
  • Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
    Publication number: 20040122069
    Abstract: Diarylcycloalkyl derivatives and their physiologically acceptable salts and physiologically functional derivatives are disclosed.
    Type: Application
    Filed: August 1, 2003
    Publication date: June 24, 2004
    Inventors: Heiner Glombik, Eugen Falk, Wendelin Frick, Stefanie Keil, Hans-Ludwig Schafer, Lothar Schwink, Wolfgang Wendler
  • Combination product of a 1,4-benzothiepine 1,1-dioxide compound with at least one other active ingredient and the use of the product
    Publication number: 20040097424
    Abstract: The present invention is directed to a 1,4-benzothiepine 1,1-dioxide compound of formula I 1
    Type: Application
    Filed: November 3, 2003
    Publication date: May 20, 2004
    Applicant: AVENTIS PHARMA DEUTSCHLAND GMBH
    Inventors: Heiner Glombik, Wendelin Frick, Hans-Ludwig Schaefer, Werner Kramer
  • Benzothiepine 1, 1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Publication number: 20040087648
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: 1
    Type: Application
    Filed: June 27, 2003
    Publication date: May 6, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Ring -substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040082561
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 29, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040077623
    Abstract: One embodiment of the invention relates to compounds of the formula I, 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 22, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
    Publication number: 20040067913
    Abstract: One embodiment of the invention relates to compounds of the formula I: 1
    Type: Application
    Filed: June 18, 2003
    Publication date: April 8, 2004
    Inventors: Gerhard Jaehne, Wendelin Frick, Stefanie Flohr, Andreas Lindenschmidt, Heiner Glombik, Werner Kramer, Hubert Heuer, Hans-Ludwig Schaefer
  • Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use
    Patent number: 6703386
    Abstract: Compounds of the formula I, for example, are disclosed, in which R1, R2, R3, R4, R5, and R6 independently of one another are (C0-C30)-alkylene-L or are the meanings given in the description, and where L is shown connected to (C0-C30)-alkylene as follows: where Rx, Ry, Rz have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: March 9, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heiner Glombik, Werner Kramer, Stefanie Flohr, Wendelin Frick, Hubert Heuer, Gerhard Jaehne, Andreas Lindenschmidt, Hans-Ludwig Schaefer
  • Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Patent number: 6642269
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: in which R1, R2, R3, R4, R5 and Z have the meanings indicated, and their physiologically tolerable salts and physiologically functional derivatives and a process for their preparation are described. The compounds are suitable, for example, as hypolipidemics.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: November 4, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Methods of treatment with combinations of statin and aryl-substituted propanolamine derivatives
    Publication number: 20030195145
    Abstract: Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described.
    Type: Application
    Filed: January 27, 2003
    Publication date: October 16, 2003
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Reinhard Kirsch, Heiner Glombik, Werner Kramer, Hans-Ludwig Schafer