Patents by Inventor Wendelin Jan Stark
Wendelin Jan Stark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210046475Abstract: The present invention relates in a first aspect to a metallic sample holder (1), in particular for capturing sample volumes for digital polymerase chain detection. The sample holder (1) comprises an array of indentations (10), wherein each indentation (11) is adapted to capture a maximal sample volume vmax, with vmax=2 nl, in particular with vmax=1 nl, in particular with vmax=0.8 nl. Each indentation (11) of the array (10) has an area cross-section section a, with a ?8*10?3 mm2, in particular with a ?5*10?3 mm2. A second aspect of the invention relates to a method for manufacturing the sample holder (1). A third aspect of the invention relates to an apparatus (200), in particular for polymerase chain reaction detection, adapted for receiving the metallic sample holder (1). A fourth aspect of the invention relates to the use of the sample holder (1) by means of the apparatus (200).Type: ApplicationFiled: December 20, 2018Publication date: February 18, 2021Inventors: Wendelin Jan Stark, Robert N. Grass, Michele Gregorini
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Publication number: 20200399401Abstract: The present invention relates to the field of antibodies useful in therapy and diagnosis. It specifically discloses bioconjugates comprising one or more antibodies bound to functionalized, magnetic nanoparticles. These bioconjugates are useful in cancer therapy, particularly for removing circulating tumor cells. The invention further pertains to specific functionalized, magnetic nanoparticles and to the manufacturing of such bioconjugates and such functionalized, magnetic nanoparticles.Type: ApplicationFiled: February 25, 2019Publication date: December 24, 2020Applicants: Universität Zürich, ETH ZurichInventors: Antoine Florent Herzog, Wendelin Jan Stark, Martin Zeltner, Beatrice Beck-Schimmer, Anja Zabel
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Patent number: 10865516Abstract: The invention relates to manufacturing processes for waterproof and breathable porous polymer membranes by coating a substrate with a dispersion comprising polymer, coated particles and diluent and removing the particles by dissolution, wherein the particles are made of organic salts, metal salts or metal oxides and the coating material is selected from carboxylic acids and alkoxy silanes. The invention further relates to dispersions to obtain such membranes, to polymer membranes obtained, to shaped articles containing such membranes; to the use of such membranes, shaped articles and intermediates.Type: GrantFiled: December 6, 2016Date of Patent: December 15, 2020Assignee: ETH ZurichInventors: Wendelin Jan Stark, Mario Stucki
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Publication number: 20200306698Abstract: The present invention relates to the manufacturing of metal organic framework (MOF) containing composite materials, particularly membranes. The inventive process comprises the steps of a phase inversion polymer formation containing pores of precursor materials and in situ formation of MOFs. The invention further relates to new MOF containing membranes; to the use of such membranes in gas separation processes and to devices comprising such membranes.Type: ApplicationFiled: May 26, 2017Publication date: October 1, 2020Inventors: Wendelin Jan STARK, Samuel HESS
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Patent number: 10655274Abstract: A threadlike metallic or metallized reinforcer, for example a thread, film, tape or cord made of carbon steel, at the periphery of which is positioned a layer of metal referred to as “surface metal” chosen from copper, nickel and copper/nickel alloys, is characterized in that this surface metal layer is itself coated, at least in part, with at least one layer of graphene; preferably, there is grafted, to this graphene, at least one functional group which can crosslink to a polymer matrix. This reinforcer of the invention is effectively protected from corrosion by virtue of the graphene present at the surface; advantageously, it can be adhesively bonded directly, without adhesion primer or addition of metal salt, to an unsaturated rubber matrix, such as natural rubber, by virtue of the possible functionalization of this graphene.Type: GrantFiled: May 20, 2015Date of Patent: May 19, 2020Assignee: COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELINInventors: Robert Nikolaus Grass, Wendelin Jan Stark, Milan Fedurco, Antonio Delfino, Jean-Paul Meraldi
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Publication number: 20200085061Abstract: The invention relates to plant protection agents in the form of a liquid formulation containing a dispersion medium and a particulate composition that comprises a specific mixture of calcium hydroxide, fatty acids and, optionally, additives. The invention also relates to non-aqueous concentrates for providing such plant protection agents, and to the production of such particulate compositions.Type: ApplicationFiled: December 11, 2017Publication date: March 19, 2020Inventor: Wendelin Jan STARK
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Patent number: 10577654Abstract: The present invention relates to core-shell particles comprising encapsulated nucleic acids—a sensing sequence and a control sequence; the invention further relates to the use of such particles as a sensing element; to methods for measuring a property of interest in a setting employing such particles; to measuring systems and analytical kits comprising such particles.Type: GrantFiled: April 19, 2016Date of Patent: March 3, 2020Assignee: ETH ZurichInventors: Robert N. Grass, Wendelin Jan Stark, Gediminas Mikutis, Michela Puddu
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Patent number: 10549021Abstract: A pump having at least a fluid pump chamber (11) and a first driver chamber (12) separated from the fluid pump chamber (11) by an elastic wall (13, 13-1, 13-2) is described with the first driver chamber (12) expanding after a chemical reaction between fuel and oxidant and driving through deformation of the elastic wall fluid out of the fluid pump chamber (11), with the main parts of the pump being made of an elastic material to be used for example as a body implant.Type: GrantFiled: October 1, 2014Date of Patent: February 4, 2020Assignee: ETH ZurichInventors: Wendelin Jan Stark, Christoph Schumacher, Roland Fuhrer, Michael Loepfe
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Patent number: 10465273Abstract: A process for depositing, with forward progression, graphene on the surface of a metallic or metallized continuous reinforcer, at the periphery of which is positioned a layer of surface metal chosen from copper, nickel and copper/nickel alloys, comprises at least one stage of flame spray pyrolysis (“FSP”), under a reducing atmosphere, of a carbon precursor which generates, in the flame, at least one carbon-based gas such as carbon monoxide which is sprayed onto the surface of the reinforcer in forward progression, and is decomposed thereon to form one or more graphene layers at the surface of the surface metal; an additional stage of graphene functionalization makes it possible to adhere the reinforcer to a polymer matrix such as rubber.Type: GrantFiled: May 20, 2015Date of Patent: November 5, 2019Assignee: COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELINInventors: Wendelin Jan Stark, Robert Nikolaus Grass, Milan Fedurco, Antonio Delfino, Jean-Paul Meraldi
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Patent number: 10457811Abstract: The present invention relates to methods for producing surface-modified calcium oxide particles having the production steps according to claim 1, novel calcium oxide particles obtained according to these methods, and uses thereof.Type: GrantFiled: February 21, 2017Date of Patent: October 29, 2019Assignee: Kalkfabrik Netstal AGInventor: Wendelin Jan Stark
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Publication number: 20180371687Abstract: The invention relates to manufacturing processes for waterproof and breathable porous polymer membranes by coating a substrate with a dispersion comprising polymer, coated particles and diluent and removing the particles by dissolution, wherein the particles are made of organic salts, metal salts or metal oxides and the coating material is selected from carboxylic acids and alkoxy silanes. The invention further relates to dispersions to obtain such membranes, to polymer membranes obtained, to shaped art ides containing such membranes; to the use of such membranes, shaped articles and intermediates.Type: ApplicationFiled: December 6, 2016Publication date: December 27, 2018Inventors: Wendelin Jan STARK, Mario STUCKI
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Patent number: 10156028Abstract: The present invention relates to the manufacturing gelatin fibers comprising the steps of: (a) preparing a two-phase composition as defined in the claims, (b) spinning the lower phase of said composition, (c) stretching the obtained fiber and (d) optional finishing steps; to new gelatin fibers and to the use thereof.Type: GrantFiled: May 21, 2014Date of Patent: December 18, 2018Assignee: ETH ZurichInventors: Philipp R. Stoessel, Robert N. Grass, Wendelin Jan Stark
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Publication number: 20180119220Abstract: The present invention relates to core-shell particles comprising encapsulated nucleic acids—a sensing sequence and a control sequence; the invention further relates to the use of such particles as a sensing element; to methods for measuring a property of interest in a setting employing such particles; to measuring systems and analytical kits comprising such particles.Type: ApplicationFiled: April 19, 2016Publication date: May 3, 2018Applicant: ETH ZURICHInventors: Robert N. GRASS, Wendelin Jan STARK, Gediminas MIKUTIS, Michela PUDDU
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Patent number: 9850531Abstract: The present invention relates to a method for protecting and. recovering nucleic acids. This method may be applied in a verification method of products using molecular code systems or it may be applied in a storage method for nucleic acids. The invention further provides specific particles, their use in secure marking; products suitable for such verification method, to processes for manufacturing such products and methods for reading the information.Type: GrantFiled: March 26, 2013Date of Patent: December 26, 2017Assignee: ETH ZurichInventors: Robert N. Grass, Wendelin Jan Stark
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Patent number: 9694517Abstract: A ready-for-use metal reinforcer, for example, of the wire or cord type, made of brass-coated carbon steel, is capable of adhering directly by vulcanization to a matrix of unsaturated rubber such as natural rubber. The surface of the reinforcer is provided with nanoparticles of at least one sulfide of a metal chosen from cobalt, copper, iron, zinc and the alloys comprising at least one of these elements. Such a reinforcer can be used as the reinforcing element of a finished article made of rubber, such as a tire.Type: GrantFiled: December 16, 2013Date of Patent: July 4, 2017Assignees: Compagnie Generale Des Etablissements Michelin, Michelin Recherche Et Technique S.A.Inventors: Antonio Delfino, Milan Fedurco, Jean Paul Meraldi, Robert Nikolaus Grass, Wendelin Jan Stark
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Publication number: 20170158860Abstract: The present invention relates to methods for producing surface-modified calcium oxide particles having the production steps according to claim 1, novel calcium oxide particles obtained according to these methods, and uses thereof.Type: ApplicationFiled: February 21, 2017Publication date: June 8, 2017Inventor: Wendelin Jan STARK
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Publication number: 20170137993Abstract: A threadlike metallic or metallized reinforcer, for example a thread, film, tape or cord made of carbon steel, at the periphery of which is positioned a layer of metal referred to as “surface metal” chosen from copper, nickel and copper/nickel alloys, is characterized in that this surface metal layer is itself coated, at least in part, with at least one layer of graphene; preferably, there is grafted, to this graphene, at least one functional group which can crosslink to a polymer matrix. This reinforcer of the invention is effectively protected from corrosion by virtue of the graphene present at the surface; advantageously, it can be adhesively bonded directly, without adhesion primer or addition of metal salt, to an unsaturated rubber matrix, such as natural rubber, by virtue of the possible functionalization of this graphene.Type: ApplicationFiled: May 20, 2015Publication date: May 18, 2017Inventors: ROBERT NIKOLAUS GRASS, WENDELIN JAN STARK, MILAN FEDURCO, ANTONIO DELFINO, JEAN-PAUL MERALDI
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Publication number: 20170121806Abstract: A process for depositing, with forward progression, graphene on the surface of a metallic or metallized continuous reinforcer, at the periphery of which is positioned a layer of surface metal chosen from copper, nickel and copper/nickel alloys, comprises at least one stage of flame spray pyrolysis (“FSP”), under a reducing atmosphere, of a carbon precursor which generates, in the flame, at least one carbon-based gas such as carbon monoxide which is sprayed onto the surface of the reinforcer in forward progression, and is decomposed thereon to form one or more graphene layers at the surface of the surface metal; an additional stage of graphene functionalization makes it possible to adhere the reinforcer to a polymer matrix such as rubber.Type: ApplicationFiled: May 20, 2015Publication date: May 4, 2017Applicant: COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELINInventors: WENDELIN JAN STARK, ROBERT NIKOLAUS GRASS, Milan Fedurco, ANTONIO DELFINO, JEAN-PAUL MERALDI
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Patent number: 9611175Abstract: The present invention relates to methods for producing surface-modified calcium oxide particles having the production steps according to claim 1, novel calcium oxide particles obtained according to these methods, and uses thereof.Type: GrantFiled: October 18, 2013Date of Patent: April 4, 2017Assignee: Kalkfabrik Nestal AGInventor: Wendelin Jan Stark
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Publication number: 20160250401Abstract: A pump having at least a fluid pump chamber (11) and a first driver chamber (12) separated from the fluid pump chamber (11) by an elastic wall (13, 13-1, 13-2) is described with the first driver chamber (12) expanding after a chemical reaction between fuel and oxidant and driving through deformation of the elastic wall fluid out of the fluid pump chamber (11), with the main parts of the pump being made of an elastic material to be used for example as a body implant.Type: ApplicationFiled: October 1, 2014Publication date: September 1, 2016Inventors: Wendelin Jan STARK, Christoph SCHUMACHER, Roland FUHRER, Michael LOEPFE