Abstract: In one embodiment, a method provides a manifest for a media program to a client. The manifest includes a set of bitrate representation links that correspond to a set of bitrates. A pointer is maintained to at least a portion of a current segment that is currently being presented in the media program. A request is received using a bitrate representation link in the set of bitrate representation links. The method then selects at least the portion of the current segment using the pointer for the bitrate that corresponds to the bitrate representation and sends the at least the portion of the current segment to the client.

Abstract: The present disclosure provides a variety of methods and compositions useful for making, sterilizing, and preserving tissues. The disclosure also features the acellular tissue matrices made by the methods.

Abstract: A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.

Abstract: In one embodiment, a method provides a manifest for a media program to a client. The manifest includes a set of bitrate representation links that correspond to a set of bitrates. A pointer is maintained to at least a portion of a current segment that is currently being presented in the media program. A request is received using a bitrate representation link in the set of bitrate representation links. The method then selects at least the portion of the current segment using the pointer for the bitrate that corresponds to the bitrate representation and sends the at least the portion of the current segment to the client.

Abstract: Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening.

Abstract: The invention provides tissue repair compositions and methods of making the tissue repair compositions. Also featured are methods of treatment using the tissue repair compositions and articles of manufacture that include the tissue repair compositions.

Abstract: In one embodiment, a method provides a manifest for a media program to a client. The manifest includes a set of bitrate representation links that correspond to a set of bitrates. A pointer is maintained to at least a portion of a current segment that is currently being presented in the media program. A request is received using a bitrate representation link in the set of bitrate representation links. The method then selects at least the portion of the current segment using the pointer for the bitrate that corresponds to the bitrate representation and sends the at least the portion of the current segment to the client.

Abstract: Devices and methods for treating or repairing openings in an body wall are provided. The devices and methods can include acellular tissue matrices. The tissue matrices can be positioned within the abdominal opening and can be used to close the opening.

Abstract: A method of transmitting media content is provided that provides for a significantly reduced chunk size. The method includes receiving one or more adaptive transport streams into a memory buffer at a HTTP streamer from a media preparation unit. The received transport streams include a plurality of switchable segments each comprising one or more delivery chunks, the switchable segments being marked with segment boundary points and the delivery chunks being marked with chunk boundary points. One or more of the delivery chunks are then transmitted from a requested switchable segment to a requesting client device until a terminating segment boundary point is reached, wherein each delivery chunk is independently decodable, and a client device can begin decoding and rendering received delivery chunks even when the HTTP streamer has not yet completely received the entire requested switchable segment from the media preparation unit.

Abstract: The invention provides tissue repair compositions and methods of making the tissue repair compositions. Also featured are methods of treatment using the tissue repair compositions and articles of manufacture that include the tissue repair compositions.

Abstract: A method is disclosed that includes: receiving, via a network digital video recorder, a request to record requested content; receiving, via a network digital video recorder at a first time, the requested content in a first format and the requested content in a second format; storing, via the network digital video recorder, the requested content in the first format; storing, via the network digital video recorder, the requested content in the second format; deleting, from network digital video recorder, the requested content in the second format after a predetermined time period; and transcoding, via an on demand transcoder, the requested content in the first format to the requested content in a third format after the predetermined time period.

Abstract: Devices and methods for treating defects in peripheral nerves are provided. The devices can include acellular arterial tissue matrices that facilitate regrowth of nerve tissue across a gap or defect in a peripheral nerve.

Abstract: The present disclosure provides a variety of methods and compositions useful for making, sterilizing, and preserving tissues. The disclosure also features the acellular tissue matrices made by the methods.

Abstract: Systems, devices and methods for adaptive switching in multicast media streams are disclosed herein. In an embodiment, a method for adaptively transmitting content to one or more users based on currently available bandwidth via internet protocol (“IP”) multicast protocol, includes: receiving a first content stream having a plurality of data packets, the first content stream encoded at a first bit rate; receiving a second content stream having a plurality of data packets, the second content stream encoded at a second bit rate, wherein the first bit rate is different than the second bit rate and wherein the first and second content streams represent the same content; transmitting the first content stream to a user; determining that the user could receive the second content stream based on available bandwidth for transmitting data to the user; and transmitting the second content stream to the user.

Abstract: A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.

Abstract: A method is disclosed that includes: receiving, via a network digital video recorder, a request to record requested content; receiving, via a network digital video recorder at a first time, the requested content in a first format and the requested content in a second format; storing, via the network digital video recorder, the requested content in the first format; storing, via the network digital video recorder, the requested content in the second format; deleting, from network digital video recorder, the requested content in the second format after a predetermined time period; and transcoding, via an on demand transcoder, the requested content in the first format to the requested content in a third format after the predetermined time period.

Abstract: A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.

Abstract: A method is disclosed that includes: receiving, via a network digital video recorder, a request to record requested content; receiving, via a network digital video recorder at a first time, the requested content in a first format and the requested content in a second format; storing, via the network digital video recorder, the requested content in the first format; storing, via the network digital video recorder, the requested content in the second format; deleting, from network digital video recorder, the requested content in the second format after a predetermined time period; and transcoding, via an on demand transcoder, the requested content in the first format to the requested content in a third format after the predetermined time period.

Abstract: A method and apparatus for an adaptive bit rate system. The method may include streaming media content at a server, determining a discontinuity in the streaming media content based on boundaries corresponding to changes in the streaming media content, and dividing the streaming media content into a plurality of variable duration segments, wherein a duration of one of the plurality of variable duration segments is to be adjusted based on the determined discontinuity to cause the one of the plurality of variable duration segments to end at the determined discontinuity in the streaming media content. The method may further include transmitting the plurality of variable duration segments of the streaming media content from the server.

Abstract: A method is disclosed that includes: receiving, via a network digital video recorder, a request to record requested content; receiving, via a network digital video recorder at a first time, the requested content in a first format and the requested content in a second format; storing, via the network digital video recorder, the requested content in the first format; storing, via the network digital video recorder, the requested content in the second format; deleting, from network digital video recorder, the requested content in the second format after a predetermined time period; and transcoding, via an on demand transcoder, the requested content in the first format to the requested content in a third format after the predetermined time period.