Patents by Inventor Wendelmoed Nelletha Eleonora van Dijk-Wolthuis

Wendelmoed Nelletha Eleonora van Dijk-Wolthuis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradable hydrogels
    Publication number: 20080131512
    Abstract: A prepolymer comprises polymerisable macromolecules, each polymerisable macromolecule comprises a polysaccharide backbone and at least two side units, wherein each of the at least two side units comprises a polymerisable group which is connected to the backbone via at least one group which is hydrolysable under physiological conditions; wherein the polymerisable group of each of the side units is independently selected from optionally alkylated and/or hydroxyalkylated acrylates and acrylamides; and wherein the at least one group which is hydrolysable under physiological conditions is selected from carbonate, lactate, glycolate, and succinate. The invention is also directed to biodegradable hydrogels useful in pharmaceutical compositions, comprising polymerized or co-polymerized prepolymers.
    Type: Application
    Filed: December 28, 2004
    Publication date: June 5, 2008
    Inventors: Wilhelmus Everhardus Hennink, Wendelmoed Nelletha Eleonora Van Dijk-Wolthuis
  • Hydrolysable hydrogels for controlled release
    Patent number: 7060296
    Abstract: The present invention relates to a biodegradable hydrogel comprising bonds which are hydrolyzable under physiological conditions. More particularly, the hydrogel consists of two interpenetrating polymer networks interconnected to one another through hydrolyzable spacers. In addition, the invention relates to a method for the preparation of a hydrogel, wherein macromolecules, e.g., polymers which contain bonds which are hydrolyzable under physiological conditions, are cross-linked in an aqueous solution.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: June 13, 2006
    Assignee: Universiteit Utrecht
    Inventors: Wilhelmus Everhardus Hennink, Wendelmoed Nelletha Eleonora van Dijk-Wolthuis
  • Hydrolysable hydrogels for controlled release
    Patent number: 6497903
    Abstract: The present invention relates to a biodegradable hydrogel comprising bonds which are hydrolysable under physiological conditions. More particularly, the hydrogel consists of two interpenetrating polymer networks interconnected to one another through hydrolysable spacers. In addition, the invention relates to a method for the preparation of a hydrogel, wherein macromolecules, e.g., polymers which contain bonds which are hydrolysable under physiological conditions, are cross-linked in an aqueous solution.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: December 24, 2002
    Inventors: Wilhelmus Everhardus Hennink, Wendelmoed Nelletha Eleonora van Dijk-Wolthuis
  • Hydrolysable hydrogels for controlled release
    Publication number: 20020131952
    Abstract: The present invention relates to a biodegradable hydrogel comprising bonds which are hydrolysable under physiological conditions. More particularly, the hydrogel consists of two interpenetrating polymer networks interconnected to one another through hydrolysable spacers. In addition, the invention relates to a method for the preparation of a hydrogel, wherein macromolecules, e.g. polymers, which contain bonds which are hydrolysable under physiological conditions, are cross-linked in an aqueous solution.
    Type: Application
    Filed: December 6, 2001
    Publication date: September 19, 2002
    Inventors: Wilhelmus Everhardus Hennink, Wendelmoed Nelletha Eleonora Van Dijk-Wolthuis