Patents by Inventor Wendy Blanda
Wendy Blanda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220096531Abstract: Embodiments described herein relate to formulations for and methods of use for eye drop formulations comprising carboxymethyl cellulose (CMC) and hyaluronic acid (HA) with an improved distribution on the cornea during blinking.Type: ApplicationFiled: August 11, 2021Publication date: March 31, 2022Inventors: Bereth J. Beard, Wendy Blanda, David Marsh, Joseph G. Vehige, Peter Simmons, Haixia Liu, Steven Matsumoto
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Publication number: 20210030590Abstract: An ocular implant including a drug releasing element and having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.Type: ApplicationFiled: February 19, 2019Publication date: February 4, 2021Applicant: Ivantis, Inc.Inventors: Wendy Blanda, Rhett Schiffman
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Publication number: 20170224823Abstract: The present invention provides intravaginal drug delivery devices, such as intravaginal rings, comprising active pharmaceutical ingredients (APIs) having terminal alkene, alkyne or carbonyl functionalities. The devices of the invention exhibit increased recovery of the active pharmaceutical ingredient from platinum-catalyzed silicone polymers due to the optimization of drug particle size and cure conditions. The present invention also provides methods of preventing unintended pregnancy in a female human, methods of preventing unintended pregnancy in a female human and HIV infection in a female human, and methods of preparing intravaginal drug delivery devices.Type: ApplicationFiled: October 22, 2015Publication date: August 10, 2017Inventors: Wendy Blanda, Jonathon Daryll Holt, Andrew Nathan Brimer, Karl Malcolm, Clare McCoy, Diarmaid Murphy, Peter John James Boyd
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Publication number: 20160235780Abstract: Embodiments described herein relate to formulations for and methods of use for eye drop formulations comprising carboxymethyl cellulose (CMC) and hyaluronic acid (HA) with an improved distribution on the cornea during blinking.Type: ApplicationFiled: April 27, 2016Publication date: August 18, 2016Inventors: Bereth J. Beard, Wendy Blanda, David Marsh, Joseph G. Vehige, Peter Simmons, Haixia Liu, Steven Matsumoto
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Publication number: 20140221309Abstract: Embodiments described herein relate to formulations for and methods of use for eye drop formulations comprising carboxymethyl cellulose (CMC) and hyaluronic acid (HA) with an improved distribution on the cornea during blinking.Type: ApplicationFiled: February 3, 2014Publication date: August 7, 2014Applicant: ALLERGAN, INC.Inventors: Bereth J. Beard, Wendy Blanda, David Marsh, Joseph G. Vehige, Peter Simmons, Haixia Liu, Steven Matsumoto
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Publication number: 20080107712Abstract: The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of hydrophilic end and hydrophobic end PLGA, and deliver active agents into an ocular region without a high burst release.Type: ApplicationFiled: October 31, 2007Publication date: May 8, 2008Applicant: ALLERGAN, INC.Inventors: Jane-Guo Shiah, Rahul Bhagat, Wendy Blanda, Thierry Nivaggioli, Lin Peng, David Chou, David Weber
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Publication number: 20070059336Abstract: Biocompatible intraocular drug delivery systems include a anti-angiogenic therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or microparticles, and combinations thereof. The therapeutic agent is released in a biologically active form, for example, the therapeutic agent may retain its three dimensional structure when released into an eye of a patient, or the therapeutic agent may have an altered three dimensional structure but retain its therapeutic activity. The therapeutic agent may be selected from the group consisting of anti-angiogenesis peptides, hormones and nucleic acid agents. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy among others.Type: ApplicationFiled: February 27, 2006Publication date: March 15, 2007Applicant: Allergan, Inc.Inventors: Patrick Hughes, Thomas Malone, Gerald De Vries, Jeffrey Edelman, Wendy Blanda, Lon Spada, Peter Baciu, Scott Whitcup
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Publication number: 20070031472Abstract: Biocompatible intraocular implants include a steroid and an auxiliary agent, where the auxiliary agent is present in an amount sufficient to lessen the severity of at least one side effect compared to the use of an otherwise identical implant lacking said auxiliary agent. The steroid and the auxiliary agent may be present on the same intraocular implant or on different implants. The steroid and auxiliary agent may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants containing the steroid and an auxiliary agent may be placed in an eye to treat one or more ocular conditions while reducing the side effects otherwise accompanying steroid use.Type: ApplicationFiled: June 23, 2006Publication date: February 8, 2007Applicant: Allergan, Inc.Inventors: Glenn Huang, Thierry Nivaggioli, Lon Spada, Hiroshi Sugimoto, Wendy Blanda, James Chang, Orest Olejnik
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Publication number: 20060233860Abstract: Biocompatible intraocular implants include an alpha-2 adrenergic receptor agonist and a polymer associated with the alpha-2 adrenergic receptor agonist to facilitate release of the alpha-2 adrenergic receptor agonist into an eye for an extended period of time. The alpha-2 adrenergic receptor agonist may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. The implants can be placed in an eye to treat one or more ocular conditions, such as an ocular vasculopathy or glaucoma, including reduction of an elevated intraocular pressure.Type: ApplicationFiled: March 31, 2006Publication date: October 19, 2006Applicant: ALLERGAN, INC.Inventors: James Chang, Lon Spada, Wendy Blanda, Werhner Orilla, James Burke, Patrick Hughes
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Publication number: 20060182783Abstract: Biocompatible intraocular drug delivery systems include a anti-angiogenic macromolecular therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or microparticles, and combinations thereof. The therapeutic agent is released in a biologically active form, for example, the therapeutic agent may retain its three dimensional structure when released into an eye of a patient, or the therapeutic agent may have an altered three dimensional structure but retain its therapeutic activity. The therapeutic agent contains a component selected from the group consisting of anti-angiogenesis peptides and nucleic acid agents. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy among others.Type: ApplicationFiled: March 8, 2006Publication date: August 17, 2006Applicant: ALLERGAN, INC.Inventors: Patrick Hughes, Gerald Devries, Jeffrey Edelman, Wendy Blanda, Lon Spada, Robert Lyons
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Publication number: 20050281861Abstract: Biocompatible intraocular drug delivery systems include a non-neurotoxic macromolecule therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or microparticles, and combinations thereof. The macromolecule therapeutic agent is released in a biologically active form, for example, the therapeutic agent may retain its three dimensional structure when released into an eye of a patient, or the therapeutic agent may have an altered three dimensional structure but retain its therapeutic activity. The therapeutic agent may be selected from the group consisting of anti-angiogenesis agents, ocular hemorrhage treatment agents, non-steroidal anti-inflammatory agents, growth factor inhibitors (such as VEGF inhibitors), growth factors, cytokines, antibodies, oligonucleotide aptamers, siRNA molecules and antibiotics.Type: ApplicationFiled: April 27, 2005Publication date: December 22, 2005Applicant: ALLERGAN, INC.Inventors: Patrick Hughes, Tom Malone, Gerald Devries, Jeffrey Edelman, Wendy Blanda, Lon Spada, Peter Baciu, Scott Whitcup
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Publication number: 20050244474Abstract: Biocompatible intraocular implants include a steroid and a polymer associated with each other to facilitate release of the steroid into an eye for a period of time greater than about two months. The steroid may be associated with a biodegradable polymer matrix, such as a matrix of a two biodegradable polymers. Or, the steroid may be associated with a polymeric coating having one or more openings effective to permit the steroid to be released into an external environment. The implants may be placed in an eye to treat one or more ocular conditions. The steroid is released from the implant for more than about two months, and may be release for more than several years.Type: ApplicationFiled: April 29, 2005Publication date: November 3, 2005Applicant: Allergan, Inc.Inventors: Glenn Huang, Thierry Nivaggioli, Lon Spada, Hiroshi Sugimoto, Wendy Blanda, James Chang, Orest Olejnik
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Publication number: 20050244473Abstract: Biocompatible intraocular implants include an anti-excitotoxic agent and a biodegradable polymer that is effective to facilitate release of the anti-excitotoxic agent into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy.Type: ApplicationFiled: April 29, 2005Publication date: November 3, 2005Applicant: ALLERGAN, INC.Inventors: Patrick Hughes, Lon Spada, Hiroshi Sugimoto, Wendy Blanda, James Chang
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Publication number: 20050244461Abstract: Systems and method are provided for treatment of an eye. The systems generally include controlled release implantable elements including a therapeutic component and a substantially inactive matrix component. The systems include such elements having controlled porosities and/or controlled surface roughness. The elements are typically bioerodible and structured to be implantable into a desired location of an eye to provide delivery of the therapeutic component to the eye. The elements exhibit relatively more controllable, more predictable, drug release rate profile in comparison to substantially identical elements without such controlled porosities and/or surface roughness.Type: ApplicationFiled: April 30, 2004Publication date: November 3, 2005Applicant: Allergan, Inc.Inventors: Thierry Nivaggioli, Wendy Blanda
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Publication number: 20050244475Abstract: Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as posterior ocular conditions.Type: ApplicationFiled: April 29, 2005Publication date: November 3, 2005Applicant: ALLERGAN, INC.Inventors: Jeffrey Edelman, Patrick Hughes, Thomas Malone, Gerald DeVries, Joan-En Chang-Lin, Jane Shiah, Thierry Nivaggioli, Lon Spada, Wendy Blanda