Patents by Inventor Wendy Breuning

Wendy Breuning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Localization and characterization of the Wilms' tumor gene
    Patent number: 6316599
    Abstract: The Wilms' tumor gene associated with 11p3 locus on the human chromosome, as well as a method of analyzing cells for the gene is described and characterized. The gene encodes a transcription unit approximately 50 kb in size and a mRNA of approximately 3 kb, which is expressed in predominantly in kidney and gonadal tissue. The gene is alternative spliced producing four very similar mRNA transcripts. The polypeptides encoded by the Wilms' tumor DNA includes four “zinc fingers” and a region rich in proline and glutamine, suggesting that the polypeptide has a role in transcription regulation.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: November 13, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Katherine M. Call, Thomas M. Glaser, Caryn Y. Ito, Alan J. Buckler, Jerry Pelletier, Daniel A. Haber, Elise A. Rose, David E. Housman, Wendy Breuning, Andre Darveau