Abstract: An individualized therapy session can be delivered to a patient using a virtual reality headset and system. In one example, the system can include an accelerometer and a processor. The processor can receive data detected by the accelerometer. The data can include head position data and head movement data. The processor can then determine a view direction of a user of the VR device using the head position data, determine a heart rate of the user by using the view direction of the user to process the head movement data, and output the heart rate of the user to a remote device. The processor can receive, from the remote device, a command to adjust a VR session presented by the VR device to the user. Based on the command, the processor can adjust one or more parameters of the VR session presented by the VR device.

Abstract: Provided are methods of producing Active Pharmaceutical Ingredient (API) grade migalastat hydrochloride, and for purifying intermediate grade migalastat hydrochloride. Further provided are methods of producing [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride (lucerastat hydrochloride) and other 1-deoxygalactonojirimycin compounds, as well as methods of purifying intermediate grade lucerastat hydrochloride and other 1-deoxygalactonojirimycin compounds.

Abstract: Provided are methods of producing Active Pharmaceutical Ingredient (API) grade migalastat hydrochloride, and for purifying intermediate grade migalastat hydrochloride. Further provided are methods of producing [(2R,3S,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride (lucerastat hydrochloride) and other 1-deoxygalactonojirimycin compounds, as well as methods of purifying intermediate grade lucerastat hydrochloride and other 1-deoxygalactonojirimycin compounds.

Abstract: Provided are methods of producing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of determining the purity of a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of distributing a batch of 1,2,3,6-tetrapivaloyl-D-galactofuranoside; 5-azido-5-deoxy-1,2,3,6-tetrapivaloyl-D-galactofuranoside; intermediate grade migalastat hydrochloride; and/or migalastat hydrochloride. Also provided are methods of assessing suitability of migalastat hydrochloride for medical use.

Abstract: Aspects and features of this disclosure relate to delivering individualized mental health therapies via networked computing devices. A mental-health-treatment-delivery server outputs a module with video content in connection with a mental health treatment protocol for a user. The mental-health-treatment-delivery server outputs a request for the user to respond to a question or to stimuli. The mental-health-treatment-delivery server receives a response from the user to the question or the stimuli. The mental-health-treatment-delivery server compares the response to stored data to determine information to present to the user. The mental-health-treatment-delivery server receives a command from the server device to present the information to the user. The mental-health-treatment-delivery server outputs the information to an interface of the user device.

Abstract: An individualized therapy session can be delivered to a patient using a virtual reality headset and system. In one example, the system can include an accelerometer and a processor. The processor can receive data detected by the accelerometer. The data can include head position data and head movement data. The processor can then determine a view direction of a user of the VR device using the head position data, determine a heart rate of the user by using the view direction of the user to process the head movement data, and output the heart rate of the user to a remote device. The processor can receive, from the remote device, a command to adjust a VR session presented by the VR device to the user. Based on the command, the processor can adjust one or more parameters of the VR session presented by the VR device.

Abstract: Aspects and features of this disclosure relate to delivering individualized mental health therapies via networked computing devices. A mental-health-treatment-delivery server outputs a module with video content in connection with a mental health treatment protocol for a user. The mental-health-treatment-delivery server outputs a request for the user to respond to a question or to stimuli. The mental-health-treatment-delivery server receives a response from the user to the question or the stimuli. The mental-health-treatment-delivery server compares the response to stored data to determine information to present to the user. The mental-health-treatment-delivery server receives a command from the server device to present the information to the user. The mental-health-treatment-delivery server outputs the information to an interface of the user device.