Patents by Inventor Wendy Shoop

Wendy Shoop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR GENERATING MALE STERILE PLANTS
    Publication number: 20240141311
    Abstract: Disclosed herein are recombinant meganucleases engineered to bind and cleave a recognition sequence in the mitochondrial DNA (mtDNA) of a eukaryotic cell, such as a plant cell. The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.
    Type: Application
    Filed: April 22, 2022
    Publication date: May 2, 2024
    Applicant: North Carolina State University
    Inventors: Ralph Dewey, Derek Jantz, James Jefferson Smith, Ginger H. Tomberlin, John Morris, Anna Matthiadis, Wendy Shoop
  • ENGINEERED MEGANUCLEASES THAT TARGET HUMAN MITOCHONDRIAL GENOMES
    Publication number: 20240084276
    Abstract: Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human mitochondrial DNA (mtDNA). The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 14, 2024
    Applicants: Precision Biosciences, Inc., University of Miami
    Inventors: James Jefferson Smith, Ginger Tomberlin, John Morris, Wendy Shoop, Carlos T. Moraes
  • Engineered meganucleases that target human mitochondrial genomes
    Patent number: 11866747
    Abstract: Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human mitochondrial DNA (mtDNA). The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.
    Type: Grant
    Filed: January 30, 2023
    Date of Patent: January 9, 2024
    Assignees: University of Miami, Precision BioSciences, Inc.
    Inventors: James Jefferson Smith, Ginger Tomberlin, John Morris, Wendy Shoop, Carlos T. Moraes
  • ENGINEERED MEGANUCLEASES THAT TARGET HUMAN MITOCHONDRIAL GENOMES
    Publication number: 20230295590
    Abstract: Disclosed herein are recombinant meganucleases engineered to recognize and cleave a recognition sequence present in the human mitochondrial DNA (mtDNA). The disclosure further relates to the use of such recombinant meganucleases in methods for producing genetically-modified eukaryotic cells, and to a population of genetically-modified eukaryotic cells wherein the mtDNA has been having modified or edited.
    Type: Application
    Filed: January 30, 2023
    Publication date: September 21, 2023
    Inventors: James Jefferson Smith, Ginger Tomberlin, John Morris, Wendy Shoop, Carlos T. Moraes