Abstract: A serving container for holding ice cream cones includes a tray body and a plurality of receptacles. The tray body includes a bottom surface, side surfaces extending perpendicular to the bottom surface, and a top surface extending perpendicular to and connecting the side surfaces. The receptacles are positioned in the tray body. Each of the receptacles has an aperture positioned in the top surface of the tray body. Each of the receptacles includes a bottom wall and a substantially cylindrical side wall extending from the bottom wall. Each of the receptacles has the shape of an inverted truncated cone designed to conform to a handle portion of an ice cream cone inserted therein.

Abstract: Methods, compositions and devices are provided based on changing the binding strength of an adhesion molecule to a ligand by changing the force exerted on the bound complex between adhesion molecule and ligand, for example by changing the shear stress acting on the complex. The adhesion molecules and their ligands of this invention bind more tightly when a force-activated bond stress, such as shear force, applied to the adhesion molecules is increased, and bond less tightly when the stress is decreased. The adhesion molecules can be isolated from their sources in nature or can remain attached to their natural sources. They can be engineered, e.g., by altering their amino acid sequences or by binding to antibodies or other particles, to alter their binding properties.

Abstract: Methods, compositions and devices are provided based on changing the binding strength of an adhesion molecule to a ligand by changing the force exerted on the bound complex between adhesion molecule and ligand, for example by changing the shear stress acting on the complex. The adhesion molecules and their ligands of this invention bind more tightly when a force-activated bond stress, such as shear force, applied to the adhesion molecules is increased, and bond less tightly when the stress is decreased. The adhesion molecules can be isolated from their sources in nature or can remain attached to their natural sources. They can be engineered, e.g., by altering their amino acid sequences or by binding to antibodies or other particles, to alter their binding properties.