Abstract: A method and apparatus for real-time, simultaneous, qualitative measurement of one or more single nucleotide polymorphisms in one or more target nucleic acids is provided. This method involves combining a polymerase chain reaction (PCR) technique with an evanescent wave technique.

Abstract: A method and apparatus for real-time, simultaneous, quantitative measurement for detecting a single nucleotide polymorphism in a target nucleic acid is provided. This method involves combining a polymerase chain reaction (PCR) technique with invader assay technique.

Abstract: A method and apparatus for determining the concentration of an analyte in a sample is provided. This method involves combining enhanced chemiluminescence with microchip capillary electrophoresis or microchip liquid chromatography.

Abstract: A method and apparatus for determining the concentration of one or more microbes in a sample is provided. This method involves filtering a sample through a filter inside a sample tube to retain the one or more microbes on the filter. The resulting filtrate, which contains or produces adenosine triphosphate, is passed through the sample tube and enters the reporter region. In the reporter region, the adenosine triphosphate in the filtrate comes in contact with a transparent porous matrix, which includes a luciferin-luciferase complex. The adenosine triphosphate interacts with the luciferin-luciferase complex to provide light response, which is measured by a detector. The light response is compared with a calibration curve to determine the total concentration of one or more microbes in a sample.

Abstract: With externally applied magnetic fields, we will push and concentrate in vivo diamagnetic Bismuth particles or unipolar magnetic particles as a confined locus, cause the locus to move to a tumor, shape it to the tumor, then use near IR to heat the particles so to destroy the tumor by thermal ablation or hyperthermia treatment. We will then cause the locus to move to other tumors, and repeat the process, so to destroy all tumors and cure the cancer.

Abstract: A reactor for the quantitative analysis of target nucleic acids using an evanescent wave detection technique and a method of use thereof is provided. The reactor includes a substrate with a cavity, a buffer layer arranged over the substrate; a cover plate arranged over the buffer layer, and inlet and outlet ports. The reactor is thermally and chemically stable for PCR processing and suitable for an evanescent wave detection technique.

Abstract: A programmable probe design of DNA micro array and detection methodology is provided. DNA probes, which are complemented with the target DNA, are designed and classified into groups according to optimum hybridization temperature. The probes are arrayed by the group and immobilized on the substrate surface of the DNA micro array. The control system, imaging system and temperature control system are programmed to cooperate with each other during the detection process. This design increases the detection capabilities of the parallel-analysis system.

Abstract: A method and apparatus for real-time, simultaneous, qualitative measurement of one or more single nucleotide polymorphisms in one or more target nucleic acids is provided. This method involves combining a polymerase chain reaction (PCR) technique with an evanescent wave technique.

Abstract: A method and apparatus for real-time, simultaneous, quantitative measurement of one or more single nucleotide polymorphisms in one or more target nucleic acids is provided. This method involves combining a ligase chain reaction (LCR), a ligase detection reaction (LDR), and/or a polymerase chain reaction (PCR) technique with an evanescent wave technique.

Abstract: A method and apparatus for real-time, simultaneous, quantitative measurement for detecting a single nucleotide polymorphism in a target nucleic acid is provided. This method involves combining a polymerase chain reaction (PCR) technique with invader assay technique.

Abstract: An apparatus includes a porous membrane for retaining antigens from a sample as the sample passes through the membrane. The apparatus also includes a first binding region within the membrane. The first binding region includes antibodies associated with a first antigen of interest. At least some of the antigens retained in the membrane are brought into contact with the first binding region by applying an electrophoresis field across the membrane. The porous membrane could also include an electrophoresis buffer. A presence of the first antigen of interest could be detected by exposing the first binding region to a chemiluminescent reagent, and a quantity of the first antigen of interest could be determined by performing a chemiluminescent assay on the binding region.

Abstract: A multi-channel microarray reader has a light source carried by a first supporting stage, a second supporting stage having a plurality of reaction assembly receiving positions, each position to receive a reaction assembly, wherein each reaction assembly includes a reaction chamber and an optical substrate to support a microarray chip, and wherein the reaction chamber and the optical substrate encapsulate a buffer solution. The reader also includes an imaging sensor positioned to detect fluorescence emitted from a single microarray chip and a motion control module to position at least one of the first and second supporting stages to cause a selected microarray chip to receive energy emitted from the light source and to position the imaging sensor to receive fluorescence from that microarray chip.

Abstract: We propose unipolar magnetic particles as medicine carriers. The whole surface of each particle is monopolar, being either north or south. The particles repel each other and are repelled by same polar external magnet. Four or more magnets that are stereo located to apply the forces to a swamp of particles from all directions may, therefore, relocate the swamp, squeeze it, reshape it, and allow it to expand.

Abstract: A method and system of interprocess communication bypasses the connection oriented protocol associated with an interprocess communication facility when the client and server are local, and thus the communication oriented protocol is unnecessary. The system determines if a client is local to a server and forms a conventional connection oriented protocol connection between the client and the server. If the client and server are local, connection oriented protocol and its associated overhead are not necessary, and the system sets pointers directly from the server socket to the client socket and from the client socket to the server socket. Thus, data may be transferred directly between client and server sockets without using connection oriented protocol, and a higher throughput is obtained. Alternatively, if the client and server are not local, data is transferred via a conventional connection oriented protocol connection. Therefore, the method and system support both local and remote connections.

Abstract: A spacecraft with a reaction wheel system can be autonomously safed by setting the solar wings to continuous tracking, determining a slew rate vector based on the total angular momentum, and slewing the spacecraft using the slew rate vector until commanded to stop autonomous safing. When the total angular momentum of the spacecraft to large to be handled by rotisserie, then the spacecraft is reoriented to align a suitable rotation vector with the system momentum. In a typical application, the spacecraft has a reaction wheel assembly with four wheels arranged to form a right regular pyramid. Two reaction wheels on opposite edges of the pyramid form a first pair and the two remaining reaction wheels forming a second pair.

Abstract: A spacecraft with a reaction wheel system can be autonomously safed by setting the solar wings to continuous tracking, determining a slew rate vector based on the total angular momentum, and slewing the spacecraft using the slew rate vector until commanded to stop autonomous safing. When the total angular momentum of the spacecraft to large to be handled by rotisserie, then the spacecraft is reoriented to align a suitable rotation vector with the system momentum. In a typical application, the spacecraft has a reaction wheel assembly with four wheels arranged to form a right regular pyramid. Two reaction wheels on opposite edges of the pyramid form a first pair and the two remaining reaction wheels forming a second pair.