Patents by Inventor Wenfu MA

Wenfu MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR MODIFYING ENDOPLASMIC RETICULUM PROCESSING OF PROTEIN
    Publication number: 20220395478
    Abstract: The present disclosure provides compositions and methods for modifying endoplasmic reticulum trafficking of proteins. Also disclosed herein are methods for treating cancer and/or enhancing cancer or viral immunotherapy in a subject by increasing the extracellular secretion levels of GRP94 in the subject. Such methods comprise administering to the subject an effective amount of 4-PBA and/or a 4-PBA analog selected from among methoxy-PBA, 3-PPA, 5-PVA, hydroxy-PPA, hydroxy-PBA, and tolyl-BA.
    Type: Application
    Filed: August 8, 2022
    Publication date: December 15, 2022
    Inventors: Jonathan Goldberg, Elena Goldberg, Wenfu Ma
  • Methods for modifying endoplasmic reticulum processing of protein
    Patent number: 11433040
    Abstract: The present disclosure provides compositions and methods for modifying endoplasmic reticulum trafficking of proteins. Also disclosed herein are methods for treating cancer and/or enhancing cancer or viral immunotherapy in a subject by increasing the extracellular secretion levels of GRP94 in the subject. Such methods comprise administering to the subject an effective amount of 4-PBA and/or a 4-PBA analog selected from among methoxy-PBA, 3-PPA, 5-PVA, hydroxy-PPA, hydroxy-PBA, and tolyl-BA.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: September 6, 2022
    Assignee: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Jonathan Goldberg, Elena Goldberg, Wenfu Ma
  • METHODS FOR MODIFYING ENDOPLASMIC RETICULUM PROCESSING OF PROTEIN
    Publication number: 20200179316
    Abstract: The present disclosure provides compositions and methods for modifying endoplasmic reticulum trafficking of proteins. Also disclosed herein are methods for treating cancer and/or enhancing cancer or viral immunotherapy in a subject by increasing the extracellular secretion levels of GRP94 in the subject. Such methods comprise administering to the subject an effective amount of 4-PBA and/or a 4-PBA analog selected from among methoxy-PBA, 3-PPA, 5-PVA, hydroxy-PPA, hydroxy-PBA, and tolyl-BA.
    Type: Application
    Filed: May 18, 2018
    Publication date: June 11, 2020
    Applicant: MEMORIAL SLOAN KETTERING CANCER CENTER
    Inventors: Jonathan Goldberg, Elena Goldberg, Wenfu MA