Patents by Inventor Weng-Onn Lui

Weng-Onn Lui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Levels and/or Sustainability of DNA-based Gene Expression
    Publication number: 20150104828
    Abstract: The invention encompasses methods for improving the level and/or sustainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/or sustainability of expression compared to original unmodified nucleic acid.
    Type: Application
    Filed: May 5, 2014
    Publication date: April 16, 2015
    Inventors: Andrew Fire, Lia Gracey, Weng-Onn Lui
  • Levels and/or sustainability of DNA-based gene expression
    Patent number: 8716462
    Abstract: The invention encompasses methods for improving the level and/or sustainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/or sustainability of expression compared to original unmodified nucleic acid.
    Type: Grant
    Filed: January 29, 2007
    Date of Patent: May 6, 2014
    Assignees: Carnegie Institution of Washington, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Andrew Fire, Lia Gracey, Weng-Onn Lui
  • Patterns of known and novel small RNAS in human cervical cancer
    Publication number: 20100234445
    Abstract: Small RNA sequences that are differentially expressed in SCCC cells are provided. The sequences find use in diagnosis of cancer, and classification of cancer cells according to expression profiles. The methods are useful for detecting cervical cancer cells, facilitating diagnosis of cervical cancer and the severity of the cancer (e.g., tumor grade, tumor burden, and the like) in a subject, facilitating a determination of the prognosis of a subject, and assessing the responsiveness of the subject to therapy.
    Type: Application
    Filed: June 30, 2009
    Publication date: September 16, 2010
    Inventors: Weng Onn Lui, Nader Pourmand, Bruce K. Patterson, Andrew Fire
  • Levels and/or Sustainability of DNA-based Gene Expression
    Publication number: 20090311786
    Abstract: The invention encompasses methods for improving the level and/or sustainability of expression for a target nucleic acid in a eukaryotic cell comprising: (a) modifying the target nucleic acid to introduce or to comprise signals that limit or constrain the positions of nucleosome cores, and (b) introducing the modified target nucleic acid into the eukaryotic cell, wherein the modified target nucleic acid has improved levels and/or sustainability of expression compared to original unmodified nucleic acid.
    Type: Application
    Filed: January 29, 2007
    Publication date: December 17, 2009
    Applicant: Carnegie Institution of Washington
    Inventors: Andrew Fire, Lia Gracey, Weng-Onn Lui