Patents by Inventor Wengang Chai

Wengang Chai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • L2A5 antibody or functional fragment thereof against tumour antigens
    Patent number: 11353460
    Abstract: This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: June 7, 2022
    Assignees: UNIVERSIDADE NOVA DE LISBOA, INSTITUTO PORTUGUÊS DE ONCOLOGIA DO PORTO FG, EPE, HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF—INSTITUTE OF RADIOPHARMACEUTICAL CANCER RESEARCH
    Inventors: Paula Alexandra Quintela Videira, Carlos Manuel Mendes Novo, Liliana Raquel Rodrigues Loureiro, Mylène Adelaide do Rosário Carrascal, José Alexandre Ribeiro de Castro Ferreira, Maria Angelina de Sá Palma, Lúcio Lara Santos, Luís Carlos Oliveira Lima, Wengang Chai, Michael Bachmann
  • L2A5 ANTIBODY OR FUNCTIONAL FRAGMENT THEREOF AGAINST TUMOUR ANTIGENS
    Publication number: 20210033616
    Abstract: This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.
    Type: Application
    Filed: January 17, 2019
    Publication date: February 4, 2021
    Inventors: Paula Alexandra Quintela VIDEIRA, Carlos Manuel Mendes NOVO, Liliana Raquel Rodrigues LOUREIRO, Mylène Adelaide do Rosário CARRASCAL, José Alexandre Ribeiro de Castro FERREIRA, Maria Angelina de Sá PALMA, Lúcio Lara SANTOS, Luís Carlos Oliveira LIMA, Wengang CHAI, Michael BACHMANN
  • Products and methods
    Publication number: 20040259142
    Abstract: An array of reducing end-tagged carbohydrate molecules immobilised on a support. The reducing end-tagged carbohydrate molecules may be neoglycolipids or glycolipids. The reducing end-tagged carbohydrate molecule may have a carbohydrate which is an oligosaccharide, monosaccharide, an N-glycan, or an O-glycan. The array may comprise one or more samples of reducing end-tagged carbohydrate molecules which comprise a homogeneous sample of carbohydrate or a heterogeneous sample of carbohydrate. The carbohydrate may be derived from a microbe, a specific cell type, a specific tissue or organ, an animal, for example a human, or a plant.
    Type: Application
    Filed: May 27, 2004
    Publication date: December 23, 2004
    Applicant: Imperial College Innovations Limited
    Inventors: Wengang Chai, Ten Feizi, Alexander Lawson