Abstract: The invention provides a compound represented by the following structural formula: (I) or a pharmaceutically acceptable salt, or a stereoisomer thereof useful for treating cancer.

Abstract: A communication method comprises that if a policy control device does not support setup of an Internet Protocol (IP) multimedia subsystem (IMS) default bearer during setup of an IMS default bearer for a terminal, the control plane gateway sends second indication information to a user plane gateway, where the second indication information indicates the control plane gateway bypasses the policy control device. When the user plane gateway receives an IMS session request from the terminal and determines that the control plane gateway bypasses the policy control device, the user plane gateway sends first indication information to the control plane gateway, and the first indication information indicates the control plane gateway to send, to the policy control device, a first request to request to establish a mapping relationship between the terminal and the control plane gateway such that an IMS session can be set up between terminals.

Abstract: This application provides a troubleshooting method and apparatus. The troubleshooting method includes obtaining key performance indicator (KPI) information of each service processor in a monitored network element; determining a faulty object according to the KPI information; determining a troubleshooting policy according to the faulty object; and sending the troubleshooting policy to a management unit in a network function virtualization (NFV) system, so that the management unit uses the troubleshooting policy to perform troubleshooting. Using the method or apparatus in this application, a problem of relatively low precision in fault locating according to a heartbeat message of a network element can be resolved.

Abstract: A traffic control method and apparatus is presented, where the method includes determining, by a back-end network element according to a type of a received service message, a priority of the service message and a resource that needs to be consumed for processing the service message; obtaining, according to the priority of the service message and usage of the resource, a quantity or an adjustment quantity of service messages of a different type to be received in a current period; and sending the quantity or the adjustment quantity of the service messages of the different type to be received in the current period to a front-end network element.

Abstract: This application provides a troubleshooting method and apparatus. The troubleshooting method includes obtaining key performance indicator (KPI) information of each service processor in a monitored network element; determining a faulty object according to the KPI information; determining a troubleshooting policy according to the faulty object; and sending the troubleshooting policy to a management unit in a network function virtualization (NFV) system, so that the management unit uses the troubleshooting policy to perform troubleshooting. Using the method or apparatus in this application, a problem of relatively low precision in fault locating according to a heartbeat message of a network element can be resolved.

Abstract: A traffic control method and apparatus is presented, where the method includes determining, by a back-end network element according to a type of a received service message, a priority of the service message and a resource that needs to be consumed for processing the service message; obtaining, according to the priority of the service message and usage of the resource, a quantity or an adjustment quantity of service messages of a different type to be received in a current period; and sending the quantity or the adjustment quantity of the service messages of the different type to be received in the current period to a front-end network element.

Abstract: The invention discloses a method for establishing a session between a caller and a callee, applying to a next generation network, after said callee picking up, which includes: restarting a session negotiation with said callee via a first application server corresponding to the callee, upon obtaining a session description protocol of said callee, sending an update request message containing a session description protocol of said callee to a second application server corresponding to the caller; renegotiating, by the second application server, session with a caller according to said session description protocol of said callee; after the caller completing session update, returning a response message containing a session description protocol of said caller to said callee. The method can realize the multi-service nesting triggering or the forwarding triggering of several flows in one service, and can guarantee the proper connection between the caller and the callee.

Abstract: Disclosed are mammalian expression vectors for expressing simultaneous expression of immunoglobulins as both a secreted and cell surface bound form.

Abstract: Disclosed are mammalian expression vectors for expressing simultaneous expression of immunoglobulins as both a secreted and cell surface bound form.

Abstract: Disclosed are mammalian expression vectors for expressing simultaneous expression of immunoglobulins as both a secreted and cell surface bound form.

Abstract: An improved optical sensor and methods for measuring the presence of various materials or constituents in a fluid sample uses reactive material(s) in a fluid environment. The reactive materials have optical properties that change in the presence of a target material that may be present in the environment. An optical emitter generates light that is directed to the reactive materials, and one or more optical detectors receive reflected light from one or more interfaces in the optical path between the emitter and the detector(s), one or more of the interfaces having a reactive material. The reactive material(s), emitter(s), and detector(s) are selected based on the desired target material to be sensed.

Abstract: An improved optical sensor and methods for measuring the presence of various materials or constituents in a fluid sample uses one or more reactive materials in a fluid environment. The reactive materials have optical properties that change in the presence of one or more target materials that may be present in the environment. One or more optical emitters generate light that is directed to the reactive material(s), and one or more optical detectors receive light from the reactive material(s), and the presence or absence of the target material is determined based on the light received at the optical detector(s). The reactive material(s), emitter(s), and detector(s) are selected based on the desired target material to be sensed.

Abstract: Disclosed are mammalian expression vectors for expressing simultaneous expression of immunoglobulins as both a secreted and cell surface bound form.

Abstract: An improved optical sensor and methods for measuring the presence of various materials or constituents in a fluid sample uses reactive material(s) in a fluid environment. The reactive materials have optical properties that change in the presence of a target material that may be present in the environment. An optical emitter generates light that is directed to the reactive materials, and one or more optical detectors receive reflected light from one or more interfaces in the optical path between the emitter and the detector(s), one or more of the interfaces having a reactive material. The reactive material(s), emitter(s), and detector(s) are selected based on the desired target material to be sensed.

Abstract: An improved optical sensor and methods for measuring the presence of various materials or constituents in a fluid sample uses one or more reactive materials in a fluid environment. The reactive materials have optical properties that change in the presence of one or more target materials that may be present in the environment. One or more optical emitters generate light that is directed to the reactive material(s), and one or more optical detectors receive light from the reactive material(s), and the presence or absence of the target material is determined based on the light received at the optical detector(s). The reactive material(s), emitter(s), and detector(s) are selected based on the desired target material to be sensed.

Abstract: The invention discloses a method for establishing a session between a caller and a callee, applying to a next generation network, after said callee picking up, which includes: restarting a session negotiation with said callee via a first application server corresponding to the callee, upon obtaining a session description protocol of said callee, sending an update request message containing a session description protocol of said callee to a second application server corresponding to the caller; renegotiating, by the second application server, session with a caller according to said session description protocol of said callee; after the caller completing session update, returning a response message containing a session description protocol of said caller to said callee. The method can realize the multi-service nesting triggering or the forwarding triggering of several flows in one service, and can guarantee the proper connection between the caller and the callee.

Abstract: The present invention discloses a method for playing audio/video files in a console at a conference in the next generation network. The method includes the following steps: the conference console sends a request for playing the audio/video files to a conference application server; the media resource server determines a media channel between the media resource server and the conference console in accordance with a request sent by the conference application server; the conference console converts a format of media streams of the audio/video files into a format supported by the media resource server, and transfers the converted media streams to the media resource server via the media channel; and the media resource server plays media stream information of the audio/video files to conference terminals. The present invention achieves playing both audio files and video files with an excellent effect, irrespective of whether the local facilities have corresponding functions of playing audio or video files.

Abstract: A multi-dimensional, micro-electromechanical assembly and the method of fabricating same. The invention enables an assembly of three-dimensional (3D) microelectromechanical systems (MEMS) using surface tension or shrinkage self assembly. That is, the invention provides a surface tension self assembly technique for rotating a MEMS element with a controlled amount of deformation to a selected angle out of the plane of a substrate. In accordance with the inventive method, multi-dimensional, micro-electromechanical assemblies are fabricated by providing a phase change material on at least one substantially planar structure mounted in a first orientation. A phase change is induced in the phase change material whereby the phase change material changes from a first state, in which the structure is disposed in the first orientation, to a second state, in which the structure is disposed in a second orientation. The MEMS elements may be fabricated using conventional surface micromachining techniques.