Abstract: The present application provides a polypeptide and a cosmetic composition or pharmaceutical composition and use thereof. The polypeptide has the following general formula: R1—X1—X2—X3—X4—X5—X6—X7—X8—R2. The present application relates to a peptide, stereoisomers thereof, a mixture of the stereoisomers, or a cosmetically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a cosmetic composition or a pharmaceutical composition thereof, and a use thereof in the preparation of the cosmetic composition or pharmaceutical composition for improving skin aging or photoaging, and treating or caring for a condition, a disorder or a disease caused by muscle contraction.

Abstract: A peptide as represented by general formula (I), a stereoisomer thereof, a mixture of the stereoisomer, or a cosmetically acceptable salt or pharmaceutically acceptable salt thereof, or a cosmetic composition or pharmaceutical composition thereof, and an application thereof for treatment or care of a disorder, an illness, or a disease of the skin or mucosa.

Abstract: The present invention relates to a hexapeptide, a cosmetic composition or a pharmaceutical composition thereof, and a use thereof, the peptide has the following general formula: R1-Phe-Phe-Trp-Phe-X1-X2-R2. The peptide of the present invention, a stereoisomer thereof, or a mixture of stereoisomers thereof, or a cosmetically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or their cosmetic compositions or pharmaceutical compositions, and their uses in the preparation of a cosmetic composition or a pharmaceutical composition for anti-inflammation and skin barrier repair.

Abstract: A peptide derivative and a cosmetic composition or pharmaceutical composition and use thereof. The peptide derivative has the following general formula: R1—Pro-Lys-Glu-Lys-R2. The peptide derivative is obtained by means of covalent binding of niacin, tranexamic acid or kojic acid with a peptide, has the effects of relieving skin inflammation reaction and inhibiting melanin generation, and can be used in the fields of cosmetics or medicines for anti-inflammation as well as whitening and freckle-removing of skin, especially for improving post-inflammation hyperpigmentation.

Abstract: Provided are a peptide derivative and a cosmetic composition or pharmaceutical composition and use thereof. The peptide derivative has a general formula as follows: R1-Gly-Pro-Gln-Gly-Pro-Gln-R2. The peptide derivative is obtained by covalently binding caffeic acid and gallic acid to peptide, respectively; and compared with single caffeic acid, gallic acid and single polypeptide, the peptide derivative has excellent skin photoaging and anti-oxidation effects, and can be applied to the fields of cosmetics, medicines, and the like.