Abstract: In an image transmission method, a first image is displayed in a messaging interface. The first image includes an interaction effect between a plurality of virtual objects. A request is received from a current user to transmit a second image that is based on the first image. A target user to which the second image is to be transmitted is determined. The second image that is generated according to object information of the determined target user and the first image is displayed in the messaging interface. The second image and the first image include the same interaction effect.

Abstract: The present disclosure provides methods, compositions, and kits for high-throughput single-cell analysis, such as nucleic acid analysis. In some embodiments, methods, compositions and kits for indexing a plurality of samples are provided. In some embodiments, methods, compositions and kits for high-throughput single-cell nucleic acid analysis, such as RNA sequencing are provided. The present disclosure allows fast, efficient and convenient cell labeling and sample pooling without being limited by cell types.

Abstract: A social processing method includes displaying a session interface of a social session comprising N social objects, N being an integer greater than 1, and each social object having an avatar, the avatar being an image configured for interacting with other social objects through an interaction behavior; obtaining configuration information, the configuration information being information on M avatars to-be-displayed of N avatars, and M being an integer less than or equal to N; and displaying the M avatars in the session interface according to the configuration information.

Abstract: Provided is a small molecule compound, which is characterized in having the structure represented by the following molecular formula: (I), wherein X1 and X2 are selected from carbon or nitrogen; G1 is a carbocyclic ring or heterocyclic ring having aromaticity; any one or more hydrogen atoms on the ring of G1 are substituted by R1; and R1 is selected from nitrogen-containing groups. The small molecule compound of the present invention can be used as a highly effective and specific JAK kinase inhibitor, specifically a Tyk2 inhibitor; and/or a JAK1 inhibitor, and/or a JAK1/Tyk2 or Tyk2/JAK1, Tyk2/Jak2 dual inhibitor.

Abstract: The present invention discloses a CEEMDAN-based method for screening and monitoring soil moisture stress in farmland, characterised by the steps: preprocessing of remote sensing images, construction of NDVI long time series, CEEMDAN decomposition, calculation of statistical descriptors, screening of soil moisture stress sequences, ground data measurement, construction of soil moisture stress characteristic curves, fitting of soil moisture stress response characteristic curves and predicting the content of soil moisture stress. The invention adopts CEEMDAN decomposition, which solves the problems of noise residue and low reconstruction accuracy in the previous methods, and the high reconstruction accuracy of decomposed component data is more conducive to capturing the transient effects of soil moisture stress, and realizes the screening and extraction of soil moisture stress by combining with the ground measured data.

Abstract: A well tracking device includes a rectangular frame including four sidewalls. The sidewalls define sets of opposing grooves, and the well tracking device is configured to receive or fit on top of a multi-well plate. The well tracking device also includes a well coordinate indicator positioned on an upper portion of the rectangular frame, that includes labels associated with columns and/or rows of the multi-well plate. The well tracking device also includes at least one slider that is configured to interface with a set of opposing grooves and slide along a width or length of the rectangular frame. The slider includes a plurality of openings disposed along the elongated shape of the slider.

Abstract: A triazolo pyrazine compound, wherein the triazolo pyrazine compound is a compound as represented by formula (I) as follows, or a stereoisomer, a geometrical isomer, a tautomer, a hydrate, a solvate, and a pharmaceutically acceptable salt or a prodrug thereof, wherein W is selected from a substituted or unsubstituted aryl or heteroaryl, X is C or N, and R is H or any substituent group. When the triazolo pyrazine compound provided by the invention is used as a Tyk2 specific inhibitor, a more targeted drug can be provided for autoimmune inflammatory diseases driven by an IL-23/Th17 axis, and the compound can be used for treating rheumatoid arthritis, psoriasis, ankylosing spondylitis, sicca syndrome, lupus erythematosus, inflammatory bowel disease, Behcet's disease, severe COVID-19 pneumonia and other diseases more safely and effectively.

Abstract: The present invention provides a small molecule compound. The small molecule compound is a compound represented by the following formula (I), or a stereoisomer, geometric isomer, tautomer, hydrate, solvate, and pharmaceutically acceptable salt or prodrug thereof, wherein R1 to R5 are each independently selected from C or N; and R is selected from cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl, or substituted heteroaryl. The small molecule compound of the present invention can inhibit the JAK kinase, and is particularly used as a JAK1/Tyk2 dual inhibitor and a Tyk2 specific inhibitor.

Abstract: A cross dipole antenna element may include a flexible substrate, a first pair of dipole arms disposed on the flexible substrate, a second pair of dipole arms disposed on the flexible substrate, a plurality of feed points disposed at a center portion of the flexible substrate and between the first and second pairs of dipole arms, a metallic plate forming a ground plane for the antenna element, and a dielectric spacer disposed between the center portion of the flexible substrate and the metallic plate. The first and second pairs of dipole arms may be operably coupled to the metallic plate at distal ends of the first and second pairs of dipole arms relative to the center portion.

Abstract: Provided in the present invention are a small molecule compound, which is the compound represented by formula (I), or a stereoisomer, a geometric isomer, a tautomer, a hydrate, a solvate, and a pharmaceutically acceptable salt or a prodrug thereof, where R1 to R4 are each independently selected from C or N, and wherein R is selected from a cycloalkyl, substituted cycloalkyl, heterocycloalkyl, substituted heterocycloalkyl, aryl, substituted aryl, heteroaryl or substituted heteroaryl. The small molecule compound of the present disclosure can inhibit a JAK kinase, and more particularly is used as a JAK1/Tyk2 dual inhibitor and a Tyk2 specific inhibitor.

Abstract: Provided in the present invention is a small molecule compound, which is characterized in that it is a compound or a stereoisomer, geometric isomer, tautomer, racemate, hydrate, solvate, metabolite, and pharmaceutically acceptable salt or prodrug of the compound as represented by the following structural formula: formula (I). The small molecule compound of the present invention is applicable as a highly efficient and specific JAK kinase inhibitor, specifically a Tyk2 inhibitor and/or a JAK1 inhibitor, and/or a JAK1/Tyk2 dual inhibitor.

Abstract: A dispenser system for dispensing a fluid product comprises: an elongated container containing the fluid product to be dispensed, a pump assembly coupled with the elongate container from the distal end, a piston which is slidably positioned in the container at the closed proximal end and contacting with the fluid product, and a standing cap. The standing cap has an opening for engaging the pump assembly, and has a supporting structure opposite to the opening, wherein the supporting structure comprises one or more supporting sections that define a supporting plane, wherein the dispenser system, when in a main standing position, stands upon the supporting structure of the standing cap, with the closed proximal end of the elongated container is on the topmost. Further the supporting structure of the standing cap has a projected area on the supporting plane which is larger than the largest cross-sectional area of the elongated container.

Abstract: An air-cooled diesel generator is provided, and relates to the technical field of diesel generator sets. The air-cooled diesel generator comprises a box body and multiple components provided in the box body, and each component is provided with a separate housing outside; a main air inlet and a main air outlet are formed in the box body, a sub-air inlet and a sub-air outlet are formed in each housing, each sub-air outlet communicates with the main air outlet through an air duct, and each sub-air inlet is provided with an air guide device. Therefore, the air-cooled diesel generator is provided which has better heat dissipation performance.

Abstract: A well tracking device includes a rectangular frame including four sidewalls. The sidewalls define sets of opposing grooves, and the well tracking device is configured to receive or fit on top of a multi-well plate. The well tracking device also includes a well coordinate indicator positioned on an upper portion of the rectangular frame, that includes labels associated with columns and/or rows of the multi-well plate. The well tracking device also includes at least one slider that is configured to interface with a set of opposing grooves and slide along a width or length of the rectangular frame. The slider includes a plurality of openings disposed along the elongated shape of the slider.

Abstract: The present technology relates to a customizable sample preparation device (e.g., liquid sample preparation device, such as a purification, clean-up, or separation device). In particular, the present technology relates to customizable devices formed from modular segments tailored to address one or more of the following: to optimize different sample and elution volumes, to incorporate various connection mechanisms to liquid handlers, to incorporate various liquid dispensing flow conditions, and to fulfill broad applications through the selection of specific resin for sample preparation. Some embodiments are directed to affinity capture devices, such as for example, Protein A affinity capture devices, utilizing a polymethacrylate-based resin. Other resins as well as other materials for processing a liquid sample are described herein.

Abstract: The present invention is a dual Ka-band, compact, high efficiency CP antenna cluster with dual band compact diplexers-polarizers that can be used as a basic building block for mobile satellite antenna arrays that require minimal dimensions and high efficiency.

Abstract: The present invention is a dual Ka-band, compact, high efficiency CP antenna cluster with dual band compact diplexers-polarizers that can be used as a basic building block for mobile satellite antenna arrays that require minimal dimensions and high efficiency.

Abstract: The present invention is a dual Ka-band, compact, high efficiency CP antenna cluster with dual band compact diplexers-polarizers that can be used as a basic building block for mobile satellite antenna arrays that require minimal dimensions and high efficiency.