Abstract: The present disclosure provides use of Clostridium ghonii combined with a tumor angiogenesis inhibitor in preparing a pharmaceutical product for treating a tumor. The present disclosure further provides a drug for treating a tumor, where the drug includes active ingredients of Clostridium ghonii and a tumor angiogenesis inhibitor.

Abstract: The present disclosure relates to use of a Clostridium ghonii spore combined with pembrolizumab in cancer treatment. It is found for the first time that the Clostridium ghonii spore combined with pembrolizumab can significantly improve a curative effect of colon cancer and reduce a dose of the pembrolizumab, and thus is efficient and low-toxic. Oncolysis by Clostridium ghonii can affect immunogenicity of a tumor microenvironment (TME) by various ways, converts an immunosuppressive state of the TME into an immune-activated state, adjusts the immunosuppressive TME, and breaks an immune tolerance. An optimal combination of the Clostridium ghonii spore and the pembrolizumab thoroughly removes about 20% of mouse tumor tissues. A benefit range of patients with tumors treated by a PD-1 antibody is expanded. The combination even has an obvious curative effect on patients failed the treatment by the PD-1 antibody.

Abstract: Methods and systems for budgeted and simplified training of deep neural networks (DNNs) are disclosed. In one example, a trainer is to train a DNN using a plurality of training sub-images derived from a down-sampled training image. A tester is to test the trained DNN using a plurality of testing sub-images derived from a down-sampled testing image. In another example, in a recurrent deep Q-network (RDQN) having a local attention mechanism located between a convolutional neural network (CNN) and a long-short time memory (LSTM), a plurality of feature maps are generated by the CNN from an input image. Hard-attention is applied by the local attention mechanism to the generated plurality of feature maps by selecting a subset of the generated feature maps. Soft attention is applied by the local attention mechanism to the selected subset of generated feature maps by providing weights to the selected subset of generated feature maps in obtaining weighted feature maps.

Abstract: In the field of biomedical technology, a PIWI-interacting RNA piR-hsa-211106 is used to prepare a targeted therapeutic drug for inhibiting proliferation of lung adenocarcinoma cells. A mechanism is as follows: after the PIWI-interacting RNA piR-hsa-211106 is constructed into an agonist or a transformant, the agonist or the transformant inhibits a tricarboxylic acid cycle process by down-regulating an expression of a pyruvate carboxylase, inhibits an energy metabolism, promotes apoptosis of the lung adenocarcinoma cells, thus inhibits growth of the lung adenocarcinoma. The PIWI-interacting RNA piR-hsa-211106 directly acts on a target site and does not produce toxic and side effects and an off-target phenomenon. Large amounts of analysis and in-vivo and in-vitro experiments show that the PIWI-interacting RNA piR-hsa-211106 has high credibility and a remarkable treatment effect, and provides a new research direction for anti-tumor therapy of lung adenocarcinoma.

Abstract: A data processing method, apparatus, and system, where the method includes: receiving a data insertion request sent by service software, where the data insertion request includes a data record, and the data record includes an object type identifier, a field value, a field identifier, and an object instance identifier; generating a field index based on the object type identifier, the field value, and the object instance identifier; generating a relationship index based on the object type identifier; writing the data record to a database; and caching an index record and an operation for the index record into a cache apparatus, where the index record includes the relationship index and the field index. Using the foregoing solution, high-performance data processing of a flat-wide table is implemented.

Abstract: A speech interaction method includes receiving, by a server, a first play message, where the first play message includes an identifier of first audio content corresponding to a first non-speech instruction. The server determines a first intent and first slot information that correspond to the first non-speech instruction. In response to the first play message, the server instructs a playback device to play the first audio content. The server receives a first speech instruction input by a user into the playback device, where a second intent or second slot information or both in the first speech instruction are incomplete. The server determines, based on the first intent and the first slot information, the second intent and the second slot information that correspond to the first speech instruction, and the server, based on the second intent and the second slot information, instructs the playback device to play second audio content.

Abstract: The disclosure relates to a generator and a wind turbine. The generator includes an active cooling loop and a passive cooling loop that are isolated from each other and both are in communication with external environment. The active cooling loop includes cavities that are in communication with each other and located at two respective ends of the generator in an axial direction, an air gap between a rotor and a stator of the generator, and radial channels arranged at intervals and distributed along the axial direction of the stator. A cooling device in communication with the external environment is disposed in the active cooling loop. The passive cooling loop includes an axial channel extending through the stator in the axial direction and an outer surface of the generator.

Abstract: A generator and a wind turbine are provided. The generator includes an active cooling circuit and a passive cooling circuit, the active cooling circuit is in communication with a closed space, and the passive cooling circuit is in communication with the external environment. The active cooling circuit includes mutually communicating chambers located at two axial ends of the generator, an air gap between a rotor and a stator of the generator, and radial channels distributed along an axial direction of the generator. The active cooling circuit is provided with a cooling device in communication with the closed space, and the stator is fixed on a fixed shaft through a stator bracket. The passive cooling circuit includes a first axial channel running through the stator, a second axial channel running through the stator bracket, and an outer surface of the generator. A heat exchanger is further arranged inside the generator.

Abstract: A generator and a wind turbine are provided. The generator includes an active cooling circuit and a passive cooling circuit, the active cooling circuit is in communication with a closed space, and the passive cooling circuit is in communication with the external environment. The active cooling circuit includes mutually communicating chambers located at two axial ends of the generator, an air gap between a rotor and a stator of the generator, and radial channels distributed along an axial direction of the generator. The active cooling circuit is provided with a cooling device in communication with the closed space, and the stator is fixed on a fixed shaft through a stator bracket. The passive cooling circuit includes a first axial channel running through the stator, a second axial channel running through the stator bracket, and an outer surface of the generator. A heat exchanger is further arranged inside the generator.

Abstract: Medical material production and preparation, and a preparation method of a 4D chitosan-based thermosensitive hydrogel. First, chitosan is dissolved in acetic acid solution; a chitosan-based thermosensitive hydrogel is printed by a 4D bioprinter and lyophilized after solvent extraction, to obtain lyophilized chitosan; subsequently, aqueous ?-sodium glycerophosphate solution is prepared with ultrapure water and ?-sodium glycerophosphate, and then aqueous carboxymethyl chitosan solution is prepared with ultrapure water and aqueous ?-sodium glycerophosphate solution are charged into and mixed well with aqueous carboxymethyl chitosan solution to prepare a mixture; finally, the lyophilized chitosan is crosslinked with the mixture to obtain the 4D chitosan-based thermosensitive hydrogel. With scientific and reliable principles thereof, the present invention solves a problem that conventional thermosensitive hydrogels have uneven pore sizes, and improves the entrapment efficiency and ability of limbal stem cells.

Abstract: The disclosure relates to a generator and a wind turbine. The generator includes an active cooling loop and a passive cooling loop that are isolated from each other and both are in communication with external environment. The active cooling loop includes cavities that are in communication with each other and located at two respective ends of the generator in an axial direction, an air gap between a rotor and a stator of the generator, and radial channels arranged at intervals and distributed along the axial direction of the stator. A cooling device in communication with the external environment is disposed in the active cooling loop. The passive cooling loop includes an axial channel extending through the stator in the axial direction and an outer surface of the generator.

Abstract: A data processing method, apparatus, and system, where the method includes: receiving a data insertion request sent by service software, where the data insertion request includes a data record, and the data record includes an object type identifier, a field value, a field identifier, and an object instance identifier; generating a field index based on the object type identifier, the field value, and the object instance identifier; generating a relationship index based on the object type identifier; writing the data record to a database; and caching an index record and an operation for the index record into a cache apparatus, where the index record includes the relationship index and the field index. Using the foregoing solution, high-performance data processing of a flat-wide table is implemented.

Abstract: The present invention provides methods, devices and systems for using and invoking an Oauth API.

Abstract: Embodiments of the present invention provide a web application interaction method, apparatus, and system that are applied to the communications field and can remove a limitation of a web app opening manner during web app interaction. The method includes: acquiring a URL of a slave web application from an invocation request, where the slave web application is an invoked web application; acquiring a window object of the slave web application from a mapping relationship between a URL and a window object of the slave web application by using the URL of the slave web application; acquiring invocation information of a master web application from the invocation request; and sending the invocation information of the master web application to a window of the slave web application according to the window object of the slave web application, where the master web application is a web application that invokes the slave web application.

Abstract: A routing method, apparatus and system are disclosed. The method includes: receiving from a service provider a service registration request which carries a service logical address, a service physical address, and a message rule; registering routing information according to the service registration request; and routing a request message of a service requestor according to the routing information. The present invention enables routing of the request message of a service requestor according to the service logical address, service physical address, and message rule, so that routing is more flexible and more convenient.

Abstract: The present invention provides methods, devices and systems for using and invoking an Oauth API.

Abstract: The present invention relates to a method for handling and replacing a service. The method for handling a composite service may include obtaining a concrete service corresponding to a service invocation segment description in a composite service logic, wherein the service invocation segment is an abstract service invocation segment or a service template invocation segment; triggering a service replacement, requesting to replace the service invocation segment with a concrete service invocation segment of the obtained concrete service; or, triggering a service invocation, requesting to generate a service invocation based on the concrete service. Accordingly, a concrete service can be dynamically selected when the composite service logic is being executed.

Abstract: The present invention relates to a method for handling and replacing a service. The method for handling a composite service may include obtaining a concrete service corresponding to a service invocation segment description in a composite service logic, wherein the service invocation segment is an abstract service invocation segment or a service template invocation segment; triggering a service replacement, requesting to replace the service invocation segment with a concrete service invocation segment of the obtained concrete service; or, triggering a service invocation, requesting to generate a service invocation based on the concrete service. Accordingly, a concrete service can be dynamically selected when the composite service logic is being executed.