Publication number: 20220177450
Abstract: The present invention relates to a piperazine amide derivative as represented by formula (I) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition thereof, and use of same as a therapeutic agent, especially as a selective Rearranged During Transfection (RET) kinase inhibitor. Ring a, ring e, X1, X2, X3, X4, R1, R2, R3, R4, R4?, R5, R5?, R6, R6?, R7, R7?, R8, m and n have the same definitions as those in the specification.
Type:
Application
Filed:
April 9, 2020
Publication date:
June 9, 2022
Applicant:
ZHEJIANG HISUN PHARMACEUTICAL CO., LTD.
Inventors:
Panpan ZHANG, Sunli YAN, Ying LI, Chenli GUO, Wenjian QIAN, Cheng YE, Zhengzheng SHI, Taishan HU, Lei CHEN