Patents by Inventor Wenjing Cao
Wenjing Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220148136Abstract: A system and method for image correction is provided. The method includes: receiving an original image; obtaining an image relating to a region of interest (ROI); detecting an artifact in the image relating to the ROI; generating an artifact image based on the artifact; and correcting the original image based on the artifact image.Type: ApplicationFiled: January 23, 2022Publication date: May 12, 2022Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yi WANG, Wenjing CAO
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Publication number: 20220144919Abstract: In one aspect, present invention provides a recombinant mutant human factor VIII having increased expression and/or secretion as compared to wild-type factor VIII. In certain embodiments, the recombinant factor VIII includes one or more amino acid substitution(s) selected from the group consisting of 186, Y105, A108, D115, Q117, F129, G132, H134, M147 and L152. In other aspects, the present invention provides FVIII encoding nucleic acids, FVIII-expression vectors, as well as methods of using the modified FVIII genes in the treatment of FVIII deficiencies, such as hemophilia A.Type: ApplicationFiled: January 24, 2022Publication date: May 12, 2022Applicant: IVYGEN CORPORATIONInventors: Weidong XIAO, Wenjing CAO, Biao DONG
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Publication number: 20220108499Abstract: The present disclosure provides a system and method for CT image reconstruction. The method may include combining an analytic image reconstruction technique with an iterative reconstruction algorithm of CT images. The image reconstruction may be performed on or near a region of interest.Type: ApplicationFiled: December 13, 2021Publication date: April 7, 2022Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Wenjing CAO, Stanislav ZABIC
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Patent number: 11261234Abstract: In one aspect, present invention provides a recombinant mutant human factor VIII having increased expression and/or secretion as compared to wild-type factor VIII. In certain embodiments, the recombinant factor VIII includes one or more amino acid substitution(s) selected from the group consisting of I86, Y105, A108, D115, Q117, F129, G132, H134, M147 and L152. In other aspects, the present invention provides FVIII encoding nucleic acids, FVIII-expression vectors, as well as methods of using the modified FVIII genes in the treatment of FVIII deficiencies, such as hemophilia A.Type: GrantFiled: October 18, 2018Date of Patent: March 1, 2022Assignee: IVYGEN CORPORATIONInventors: Weidong Xiao, Wenjing Cao, Biao Dong
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Patent number: 11232543Abstract: A system and method for image correction is provided. The method includes: receiving an original image; pre-correcting the original image; generating correction data based on the original image and the pre-corrected image; weighting the original image and the pre-corrected image based on the correction data; and generating a corrected image based on the weighting.Type: GrantFiled: December 30, 2019Date of Patent: January 25, 2022Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yi Wang, Wenjing Cao
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Patent number: 11216992Abstract: The present disclosure provides a system and method for CT image reconstruction. The method may include combining an analytic image reconstruction technique with an iterative reconstruction algorithm of CT images. The image reconstruction may be performed on or near a region of interest.Type: GrantFiled: April 20, 2020Date of Patent: January 4, 2022Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Wenjing Cao, Stanislav Zabic
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Publication number: 20210390694Abstract: The present disclosure discloses methods and systems for image quality optimization. The method may include obtaining an image to be processed. The method may also include determining at least one related feature of the image. The at least one related feature may include at least one of an acquisition parameter feature relating to the image, an imaging parameter feature relating to the image, an imaging subject feature of an imaging subject, or a quality feature of the image. The method may also include inputting the image and the at least one related feature into an image processing model. The method may also include determining an optimized image of the image based on an output of the image processing model.Type: ApplicationFiled: August 30, 2021Publication date: December 16, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yifu MAO, Liyi ZHAO, Wenjing CAO
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Publication number: 20210225046Abstract: The disclosure relates to systems and methods for iterative reconstruction. Raw data detected from a plurality of angles by an imaging device may be obtained. A first seed image may be generated by performing a filtered back projection on the raw data. A first air mask may be determined by performing a minimum value back projection (BP) on the raw data. One or more images may be reconstructed by performing an iterative reconstruction based on the first seed image, the first air mask, and the raw data.Type: ApplicationFiled: April 2, 2021Publication date: July 22, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Stanislav ZABIC, Patrick KLING, Wenjing CAO, Alexander ZAMYATIN, Zhicong YU, Haohua SUN
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Publication number: 20210142476Abstract: Systems and methods for image optimization are provided. The system may obtain an image to be processed. The system may determine a quality feature of the image. The system may input the image and the quality feature into an image processing model. The system may also determine an optimized image of the image based on an output of the image processing model.Type: ApplicationFiled: December 16, 2020Publication date: May 13, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Wenjing CAO
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Publication number: 20210125383Abstract: The present disclosure relates to methods, systems, and non-transitory computer readable mediums for reconstructing an image. Image data may be obtained, wherein the image data may be generated by a detector array. A weighting window may be determined based on at least one parameter relating to the detector array. A first set of data may be determined based on the image data and the weighting window. An objective function associated with a target image may be determined based on the first set of data, wherein the objective function may include a first model, the first model may represent a difference between the target image and the first set of data, and the first model may be identified based on the first set of data. The target image may be reconstructed by performing a plurality of iterations based on the objective function.Type: ApplicationFiled: January 5, 2021Publication date: April 29, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Wenjing CAO
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Patent number: 10977840Abstract: The disclosure relates to systems and methods for iterative reconstruction. Raw data detected from a plurality of angles by an imaging device may be obtained. A first seed image may be generated by performing a filtered back projection on the raw data. A first air mask may be determined by performing a minimum value back projection (BP) on the raw data. One or more images may be reconstructed by performing an iterative reconstruction based on the first seed image, the first air mask, and the raw data.Type: GrantFiled: November 30, 2018Date of Patent: April 13, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Stanislav Zabic, Patrick Kling, Wenjing Cao, Alexander Zamyatin, Zhicong Yu, Haohua Sun
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Publication number: 20210104023Abstract: The present disclosure relates to systems and methods for image reconstruction. The system may obtain an initial image to be processed. The system may generate a reconstructed image by performing a plurality of iteration steps on the initial image. Each of the plurality of iteration steps may include a first optimization operation and at least one second optimization operation. The first optimization operation and the at least one second optimization operation may be executed sequentially. The first optimization operation may include receiving an image to be processed in the iteration step and determining an updated image by preliminarily optimizing the image to be processed. The at least one second optimization operation may include determining an optimized image by reducing interference information of the updated image and designating the optimized image as a next image to be processed in a next iteration step. The interference information may include noise information and/or artifact information.Type: ApplicationFiled: December 17, 2020Publication date: April 8, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Wenjing CAO, Haohua SUN, Liyi ZHAO
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Publication number: 20210082161Abstract: A system for imaging reconstruction is provided. The system may obtain a first set of image data of a subject acquired by a scanner and a second set of image data of the subject acquired by the scanner. The first set of image data may correspond to a first angle range of the scanner. The second set of image data may correspond to a second angle range of the scanner. The first angle range may be different from the second angle range. The system may also generate a first image based on the first set of image data and generate a second image based on the second set of image data. The system may further generate a target image based on the first image and the second image.Type: ApplicationFiled: November 12, 2020Publication date: March 18, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Wenjing CAO, Rengcai YANG
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Publication number: 20210049795Abstract: The present disclosure relates to systems and methods for medical imaging. The method may include obtain scanning data and at least one prior image of a subj etc. The method may include determining a restriction factor for each of the at least one prior image based on the scanning data. The restriction factor of the each prior image may relate to a motion of the subject corresponding to the scanning data. The method may include determining an objective function based on the restriction factor. The method may also include reconstructing, using the objective function, a target image of the subject based on the scanning data and the at least one prior image.Type: ApplicationFiled: October 28, 2020Publication date: February 18, 2021Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Wenjing CAO
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Patent number: 10896526Abstract: The present disclosure relates to methods, systems, and non-transitory computer readable mediums for reconstructing an image. Image data may be obtained, wherein the image data may be generated by a detector array. A weighting window may be determined based on at least one parameter relating to the detector array. A first set of data may be determined based on the image data and the weighting window. An objective function associated with a target image may be determined based on the first set of data, wherein the objective function may include a first model, the first model may represent a difference between the target image and the first set of data, and the first model may be identified based on the first set of data. The target image may be reconstructed by performing a plurality of iterations based on the objective function.Type: GrantFiled: September 29, 2017Date of Patent: January 19, 2021Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventor: Wenjing Cao
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Publication number: 20200398082Abstract: A method may include obtaining first image data relating to a region of interest (ROI) of a first subject. The first image data corresponding to a first equivalent dose level may be acquired by a first device. The method may also include obtaining a model for denoising relating to the first image data and determining second image data corresponding to an equivalent dose level higher than the first equivalent dose level based on the first image data and the model for denoising. In some embodiments, the method may further include determining information relating to the ROI of the first subject based on the second image data and ecording the information relating to the ROI of the first subject.Type: ApplicationFiled: September 7, 2020Publication date: December 24, 2020Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Haining SUN, Guotao QUAN, Yuan BAO, Wenjing CAO
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Publication number: 20200380640Abstract: The embodiments of the present disclosure disclose methods and systems for determining a ring artifact. The method for determining the ring artifact may include: obtaining an original image; mapping a plurality of pixels in the original image to a polar coordinate image; determining a protection region in the polar coordinate image; obtaining a smooth image by smoothing at least one region in the polar coordinate image other than the protection region; generating a residual image based on the polar coordinate image and the smooth image; determining a location of the ring artifact in the original image based on the residual image. In the present disclosure, the original image may be mapped to a trapezoidal region or a triangular region in the polar coordinate image, and the gradient angle image may be used for image processing, which may reduce the influence of noise. An accurate location of the ring artifact may be determined, and information for imaging device detection and air correction may be provided.Type: ApplicationFiled: April 30, 2020Publication date: December 3, 2020Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Yuan BAO, Yi WANG, Wenjing CAO, Xiang LI
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Publication number: 20200360729Abstract: A method may include obtaining first image data relating to a region of interest (ROI) of a first subject. The first image data corresponding to a first equivalent dose level may be acquired by a first device. The method may also include obtaining a model for denoising relating to the first image data and determining second image data corresponding to an equivalent dose level higher than the first equivalent dose level based on the first image data and the model for denoising. In some embodiments, the method may further include determining information relating to the ROI of the first subject based on the second image data and recording the information relating to the ROI of the first subject.Type: ApplicationFiled: July 31, 2020Publication date: November 19, 2020Inventors: Haining SUN, Guotao QUAN, Yuan BAO, Wenjing CAO
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Publication number: 20200360730Abstract: A method may include obtaining first image data relating to a region of interest (ROI) of a first subject. The first image data corresponding to a first equivalent dose level may be acquired by a first device. The method may also include obtaining a model for denoising relating to the first image data and determining second image data corresponding to an equivalent dose level higher than the first equivalent dose level based on the first image data and the model for denoising. In some embodiments, the method may further include determining information relating to the ROI of the first subject based on the second image data and recording the information relating to the ROI of the first subject.Type: ApplicationFiled: July 31, 2020Publication date: November 19, 2020Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Haining SUN, Guotao QUAN, Yuan BAO, Wenjing CAO
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Patent number: 10765890Abstract: A method may include obtaining first image data relating to a region of interest (ROI) of a first subject. The first image data corresponding to a first equivalent dose level may be acquired by a first device. The method may also include obtaining a model for denoising relating to the first image data and determining second image data corresponding to an equivalent dose level higher than the first equivalent dose level based on the first image data and the model for denoising. In some embodiments, the method may further include determining information relating to the ROI of the first subject based on the second image data and ecording the information relating to the ROI of the first subject.Type: GrantFiled: December 17, 2018Date of Patent: September 8, 2020Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.Inventors: Haining Sun, Guotao Quan, Yuan Bao, Wenjing Cao