Abstract: The present invention discloses a circulating multidimensional liquid chromatography and application thereof. The liquid chromatography comprises an infusion device, a sampling device, a collecting-resampling device, a chromatographic column switching device and a detecting device which are connected sequentially, wherein the collecting-resampling device comprises a collecting valve and a sample ring, and the collecting valve is connected with the sample ring; the sampling device is successively connected with the collecting valve and the chromatographic column switching device; the detecting device is also connected with the collecting valve; and the collecting valve is a three-slot three-position multi-way valve.

Abstract: The present disclosure belongs to the technical field of health food, and in particular, relates to the use of PAYCS in the regulation of intestinal flora, metabolites, and brain neurotransmitters. PAYCS remedies scopolamine-induced memory impairment in mice through target oxidation, inflammatory stress and regulation of the intestinal microorganism-metabolite-brain neurotransmitter axis through PAYCS. PAYCS improves the memory pathway through the intestinal microorganism-metabolite-neurotransmitter axis. PAYCS can significantly reduce serum MDA and LDH levels and significantly increase liver SOD content. PAYCS-H inhibits the increase of liver TNF-? and IL-1?, while PAYCS-L can only reduce the content of TNF-? in the liver. Thus, PAYCS-L changes the ratio of Bacteroides/Firmicutes and increases the relative abundance of plants such as Cactaceae and Prevotellaceae, improving the neurotransmitters associated with the metabolism of tryptophan in the brain.

Abstract: An authentication method and device, authentication centre and system are provided. The method comprises: receiving at least one access request and obtaining sub-key information from the access request; generating a group key according to the obtained sub-key information, and interacting with the network side according to the group key to perform the group authentication. The solution can solve the problem that the one-to-one authentication causes network load in the present art, implement the authentication of multiple nodes at one time, reduce network resources and the network load of the server, and can be appropriate for the authentication of the terminal nodes in the internet of things, and can greatly improve the availability of services in the internet of things.

Abstract: An authentication method and device, authentication centre and system are provided. The method comprises: receiving at least one access request and obtaining sub-key information from the access request; generating a group key according to the obtained sub-key information, and interacting with the network side according to the group key to perform the group authentication. The solution can solve the problem that the one-to-one authentication causes network load in the present art, implement the authentication of multiple nodes at one time, reduce network resources and the network load of the server, and can be appropriate for the authentication of the terminal nodes in the internet of things, and can greatly improve the availability of services in the internet of things.