Patents by Inventor Wenliang YAO

Wenliang YAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12257582
    Abstract: The present disclosure discloses a sample preliminary screening chip, a specimen detecting method and a screening device. A data processor may be configured to control a sample solution containing a specimen to be added into a preliminary screening inlet of the sample preliminary screening chip, and control the sample solution in the preliminary screening inlet to enter a channel, successively to flow through a first preliminary screening area and a second preliminary screening area, and to flow out from a preliminary screening outlet so as to store a liquid with the specimen in a first preliminary screening area. In this way, the liquid containing the specimen may be screened preliminarily.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: March 25, 2025
    Assignees: Beijing BOE Sensor Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Hui Liao, Yingying Zhao, Wenliang Yao, Bolin Fan, Nan Zhao, Le Gu, Yongjia Gao
  • Patent number: 12251698
    Abstract: The disclosure provides a micro-fluidic chip, and belongs to the field of chip technology. The microfluidic chip provided in the present disclosure includes a plurality of microfluidic units, each microfluidic unit includes an operation region and a transition region located on at least one side of the operation region, the transition regions at adjacent side of two adjacent microfluidic units are disposed opposite to each other. Each microfluidic unit includes: a first substrate; a first electrode layer disposed on the first substrate, the first electrode layer including a plurality of first sub-electrodes located in the operation region and at least one second sub-electrode located in the transition region, and the at least one second sub-electrode configured to drive a droplet to move from one of the plurality of microfluidic units to an adjacent microfluidic unit.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: March 18, 2025
    Assignees: Beijing BOE Sensor Technology Co., Ltd., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Qiuxu Wei, Wenliang Yao, Yingying Zhao, Le Gu, Bolin Fan, Yongjia Gao
  • Patent number: 12226775
    Abstract: An embodiment of the present disclosure provides a microfluidic chip, including: a first substrate; wherein the first substrate includes a first base, a first electrode layer on the first base; the first electrode layer includes a plurality of first electrodes at intervals along a first direction, wherein a cross-sectional shape of the first electrode parallel to the first base is a centrosymmetric shape, and the cross-sectional shape includes: a first boundary and a second boundary opposite to each other in the first direction; a shape of the first boundary is a centrosymmetric curve, a distance between two end points of the first boundary in a second direction perpendicular to the first direction is less than a length of the first boundary; the second boundary has a same shape and length as the first boundary, and the first and second boundaries are parallel to each other in the first direction.
    Type: Grant
    Filed: September 25, 2020
    Date of Patent: February 18, 2025
    Assignee: BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Qiuxu Wei, Yingying Zhao, Wenliang Yao, Bolin Fan, Le Gu, Yongjia Gao
  • Publication number: 20240316553
    Abstract: A detection system applied to detection of microfluidic chips, includes: a detection chip including a base substrate, an electrode layer and a microfluidic channel layer for accommodating a sample solution having magnetic beads, the base substrate is provided with a bearing surface, the electrode layer is on the bearing surface, the microfluidic channel layer is on the side of the electrode layer away from the base substrate, the electrode layer includes electrodes including at least one strong magnetic electrode and driving electrodes; a magnetic field device being on the side of the base substrate away from the electrode layer, and having a strong magnetic region corresponding one to one to the strong magnetic electrode; a driving mechanism being connected to the magnetic field device, and driving the magnetic field device to approach or move away from the detection chip in a direction that is perpendicular to the bearing surface.
    Type: Application
    Filed: September 29, 2021
    Publication date: September 26, 2024
    Inventors: Le GU, Wenliang YAO, Yingying ZHAO, Bolin FAN, Qiuxu WEI, Yongjia GAO, Li YANG
  • Publication number: 20240238781
    Abstract: A digital microfluidics chip and a drive method thereof, and a digital microfluidics apparatus are provided. The digital microfluidics chip includes a first substrate (1) and a second substrate (2) which are oppositely disposed, the first substrate (1) is provided with a plurality of drive regions for driving a droplet to move, at least one drive region includes a drive transistor (50), a drive electrode (60), and a storage capacitor, the drive electrode (60) is connected with the drive transistor (50) and the storage capacitor respectively, and the storage capacitor is configured to be charged when the drive transistor (50) is turned on, and to maintain a voltage signal on the drive electrode (60) when the drive transistor (50) is turned off.
    Type: Application
    Filed: October 27, 2021
    Publication date: July 18, 2024
    Inventors: Yingying ZHAO, Le GU, Bolin FAN, Wenliang YAO, Qiuxu WEI, Yongjia GAO, Li YANG
  • Publication number: 20240207852
    Abstract: A microfluidic substrate has a first straight region, a second straight region, and a first turning region, which is substantially of a ring sector and includes a first arc edge and a second arc edge that are opposite. The microfluidic substrate includes first straight driving electrodes in the first straight region, second straight driving electrodes in the second straight region, and turning driving electrodes the first turning region. A border of each turning driving electrode includes at least one first reference point coinciding with the first arc edge and at least one second reference point coinciding with the second arc edge. A radius of the first arc edge is greater than or equal to (?{square root over (3)}?1) times of a first dimension of a reference electrode, and a radius of the second arc edge is greater than or equal to 3/2 times of the first dimension of the reference electrode.
    Type: Application
    Filed: September 2, 2021
    Publication date: June 27, 2024
    Inventors: Bolin FAN, Wenliang YAO, Yingying ZHAO, Le GU, Yongjia GAO, Qiuxu WEI, Li YANG
  • Publication number: 20240084369
    Abstract: A digital microfluidic apparatus and a driving method therefor. The digital microfluidic apparatus comprises a digital microfluidic chip (10), a thermal control apparatus (20), and an elastic support apparatus (30). The digital microfluidic chip (10) is provided with a droplet channel (91), and the droplet channel (91) is configured to allow droplets (90) to move therein; the thermal control apparatus (20) is disposed on one side of the digital microfluidic chip (10), and is configured to generate at least two independent and non-interference hot zones in the droplet channel (91), and control the temperature of each hot zone; and the elastic support apparatus (30) is disposed on the side of the thermal control apparatus (20) away from the digital microfluidic chip (10), and is configured to drive the thermal control apparatus (20) to be pasted on the surface of the digital microfluidic chip (10).
    Type: Application
    Filed: July 21, 2022
    Publication date: March 14, 2024
    Inventors: Qiuxu WEI, Wenliang YAO, Yongjia GAO, Bolin FAN, Yingying ZHAO, Le GU, Li YANG
  • Patent number: 11865538
    Abstract: A biological detection chip, a biological detection device, and a detection method thereof are disclosed. The biological detection chip includes a first base substrate and a plurality of detection units arranged in an array along a row direction and a column direction on the first base substrate. Each of the plurality of detection units includes a thin film transistor and an electrode, the thin film transistor is on the first base substrate and includes a gate electrode, a source electrode, and a drain electrode, and the electrode is on a side of the thin film transistor away from the first base substrate and is connected to the drain electrode, and the electrode is configured to carry a biological material to be detected.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 9, 2024
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Wenliang Yao, Nan Zhao, Peizhi Cai, Fengchun Pang, Yue Geng, Le Gu, Yuelei Xiao, Hui Liao, Yingying Zhao, Bolin Fan
  • Patent number: 11684916
    Abstract: A chip for polymerase chain reaction, a method of operating a chip for polymerase chain reaction, and a reaction device are provided. The chip includes: a sample adding region, a mixing region, a temperature cycling region in a sequential arrangement, and at least one driving unit group. The at least one driving unit group includes a plurality of driving units and is configured to drive a liquid drop to move and sequentially pass through the sample adding region, the mixing region, and the temperature cycling region.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: June 27, 2023
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.
    Inventors: Wenliang Yao, Nan Zhao, Haochen Cui, Peizhi Cai, Fengchun Pang, Yue Geng, Le Gu, Yuelei Xiao, Hui Liao, Yingying Zhao, Chuncheng Che
  • Patent number: 11583855
    Abstract: The present disclosure discloses a microfluidic structure, a microfluidic chip and a detection method. The microfluidic structure includes: a first base substrate and a second base substrate opposite to each other, an antibody area located between the first base substrate and the second base substrate and storing an enzyme-labeled first antibody, a cleaning area storing cleaning liquid, a signal substrate area storing a signal substrate solution and a detection area with a second antibody and an ion sensitive film fixed thereon, wherein all channel areas from the antibody area, the cleaning area and the signal substrate area to the detection area each have a driving electrode structure driving liquid drops to move; and the detection area has a thin film transistor connected with the ion sensitive film.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: February 21, 2023
    Assignees: Beijing BOE Sensor Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Hui Liao, Yingying Zhao, Bolin Fan, Wenliang Yao, Nan Zhao, Le Gu, Yongjia Gao
  • Patent number: 11577246
    Abstract: A microfluidic device and a detection method for the microfluidic device are provided. The microfluidic device includes a driving substrate configured to drive a movement of a droplet; and a position detector configured to detect a position of the droplet on the driving substrate.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: February 14, 2023
    Assignees: Beijing BOE Sensor Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Le Gu, Peizhi Cai, Fengchun Pang, Yue Geng, Yingying Zhao, Haochen Cui, Yuelei Xiao, Hui Liao, Wenliang Yao, Nan Zhao
  • Publication number: 20220403306
    Abstract: Disclosed are a substrate for a microfluidic device, a microfluidic device, a driving method of the microfluidic device, and a method of manufacturing a substrate for the microfluidic device. The substrate includes: a first base substrate; a first electrode layer on the first base substrate, the first electrode layer including a plurality of drive electrodes. The plurality of drive electrodes define at least one flow channel and at least one functional area in the first substrate, the at least one functional area includes a reagent area, the at least one flow channel includes a reagent area flow channel, the reagent area includes a reagent area liquid storage portion and a droplet shape changing portion, the droplet shape changing portion is adjacent to the reagent area flow channel, and the reagent liquid storage portion is on a side of the droplet shape changing portion away from the reagent area flow channel.
    Type: Application
    Filed: December 25, 2020
    Publication date: December 22, 2022
    Inventors: Bolin FAN, Le GU, Yingying ZHAO, Wenliang YAO, Yongjia GAO, Qiuxu WEI
  • Publication number: 20220395832
    Abstract: The present disclosure provides a substrate for driving droplets, a manufacturing method thereof, and a microfluidic device. The substrate includes a first base substrate a plurality of leads on the first base substrate a plurality of driving electrodes on a side of the plurality of leads away from the first base substrate and a shielding electrode on the side of the plurality of leads away from the first base substrate and grounded. Each of the plurality of leads is electrically connected to at least one of the plurality of driving electrodes, an orthographic projection of the shielding electrode on the first base substrate and an orthographic projection of at least one of the plurality of leads on the first base substrate at least partially overlap, and the shielding electrode is electrically insulated from the plurality of driving electrodes.
    Type: Application
    Filed: December 25, 2020
    Publication date: December 15, 2022
    Inventors: Bolin FAN, Le GU, Yingying ZHAO, Wenliang YAO, Yongjia GAO, Qiuxu WEI
  • Publication number: 20220395826
    Abstract: The present disclosure relates to a microfluidic substrate, a microfluidic device and a driving method thereof. The microfluidic substrate includes a first area, the first area includes a first module for generating droplets, the first module includes a first electrode pair and a second electrode pair, and the first electrode pair and the second electrode pair are arranged in a crisscross pattern. The first electrode pair includes a first electrode and a second electrode, and the second electrode pair includes a third electrode and a fourth electrode.
    Type: Application
    Filed: December 25, 2020
    Publication date: December 15, 2022
    Inventors: Bolin FAN, Yongjia GAO, Yingying ZHAO, Le GU, Wenliang YAO, Qiuxu WEI
  • Patent number: 11498068
    Abstract: A microfluidic device, a microfluidic detection assembly and a detection method for the microfluidic device. The microfluidic device includes a first substrate and a second substrate; the first substrate and the second substrate are oppositely arranged to define a channel between the first substrate and the second substrate, the channel is configured for liquid to flow, the first substrate includes a base substrate and a plurality of control assemblies which are arranged on the base substrate along an extending direction of the channel, each of the plurality of control assemblies includes: a first electrode, a second electrode and a plurality of coils, and the first electrode is configured to input currents into the plurality of coils, and the plurality of coils are connected in parallel to the second electrode.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: November 15, 2022
    Assignees: BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD., Beijing BOE Technology Development Co., Ltd.
    Inventors: Wenliang Yao, Haochen Cui, Peizhi Cai, Yuelei Xiao, Fengchun Pang, Yue Geng, Le Gu, Nan Zhao, Hui Liao, Yingying Zhao, Chuncheng Che
  • Publication number: 20220341925
    Abstract: The present disclosure relates to a digital microfluidic chemiluminescence detection chip, a detection method and a detection device. The digital microfluidic chemiluminescence detection chip includes a first baseplate and a second baseplate disposed oppositely. A cavity formed by the first and second baseplate includes a mixing and incubating area for combining an antigen, a magnetic particle antibody and an antibody, a luminescence detection area for chemiluminescence and detecting an optical signal, and a communication path for communicating the mixing and incubating area and the luminescence detection area. The first baseplate is provided with a drive array for driving sample solution to move and an optical sensing array for acquiring a luminescence signal of the sample solution. The drive array corresponds to positions of the mixing and incubating area, the luminescence detection area and the communication path. The optical sensing array corresponds to a position of the luminescence detection area.
    Type: Application
    Filed: February 7, 2021
    Publication date: October 27, 2022
    Inventors: Yue LI, Wenliang YAO, Nan ZHAO, Yongjia GAO, Bolin FAN, Le GU, Hui LIAO, Yingying ZHAO
  • Publication number: 20220314217
    Abstract: The present disclosure provides a microfluidic chip, and belongs to the field of biological detection technology. The microfluidic chip is divided into a middle region and a peripheral region surrounding the middle region; the middle region includes a liquid storage region and a detection region; the microfluidic chip includes a first substrate and a second substrate opposite to each other; the first substrate includes a first base plate and a first electrode layer; the second substrate includes a second base plate and a second electrode layer; wherein a liquid storage tank and a liquid inlet are on a side of the first base plate proximal to the second substrate, the liquid inlet penetrates through a bottom of the liquid storage tank; the liquid storage tank and the liquid inlet are both in the liquid storage region.
    Type: Application
    Filed: January 29, 2021
    Publication date: October 6, 2022
    Inventors: Le GU, Yingying ZHAO, Wenliang YAO, Bolin FAN, Yongjia GAO, Qiuxu WEI
  • Publication number: 20220314223
    Abstract: An embodiment of the present disclosure provides a microfluidic chip, including: a first substrate; wherein the first substrate includes a first base, a first electrode layer on the first base; the first electrode layer includes a plurality of first electrodes at intervals along a first direction, wherein a cross-sectional shape of the first electrode parallel to the first base is a centrosymmetric shape, and the cross-sectional shape includes: a first boundary and a second boundary opposite to each other in the first direction; a shape of the first boundary is a centrosymmetric curve, a distance between two end points of the first boundary in a second direction perpendicular to the first direction is less than a length of the first boundary; the second boundary has a same shape and length as the first boundary, and the first and second boundaries are parallel to each other in the first direction.
    Type: Application
    Filed: September 25, 2020
    Publication date: October 6, 2022
    Inventors: Qiuxu WEI, Yingying ZHAO, Wenliang YAO, Bolin FAN, Le GU, Yongjia GAO
  • Publication number: 20220314216
    Abstract: A micro-fluidic chip is provided. The micro-fluidic chip includes: a first base substrate; a first electrode on the first base substrate and electrically coupled to a wire at a driving end; a second electrode on a side of the first electrode away from the first base substrate and spaced apart and electrically insulated from the first electrode, the second electrode including a plurality of sub-blocks of the second electrode, and an orthographic projection of the second electrode on the first base substrate being at least partially overlapped with an orthographic projection of the first electrode on the first base substrate; and voltage-dividing resistors coupled to the plurality of sub-blocks of the second electrode in one-to-one correspondence and electrically coupled to a ground wire.
    Type: Application
    Filed: September 29, 2020
    Publication date: October 6, 2022
    Inventors: Bolin FAN, Yingying ZHAO, Le GU, Wenliang YAO, Hui LIAO, Yongjia GAO, Qiuxu WEI
  • Publication number: 20220226816
    Abstract: The disclosure provides a micro-fluidic chip, and belongs to the field of chip technology. The microfluidic chip provided in the present disclosure includes a plurality of microfluidic units, each microfluidic unit includes an operation region and a transition region located on at least one side of the operation region, the transition regions at adjacent side of two adjacent microfluidic units are disposed opposite to each other. Each microfluidic unit includes: a first substrate; a first electrode layer disposed on the first substrate, the first electrode layer including a plurality of first sub-electrodes located in the operation region and at least one second sub-electrode located in the transition region, and the at least one second sub-electrode configured to drive a droplet to move from one of the plurality of microfluidic units to an adjacent microfluidic unit.
    Type: Application
    Filed: September 30, 2021
    Publication date: July 21, 2022
    Inventors: Qiuxu WEI, Wenliang YAO, Yingying ZHAO, Le GU, Bolin FAN, Yongjia GAO