Patents by Inventor Wenmin Yuan

Wenmin Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230330259
    Abstract: The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising synthetic HDL (sHDL) nanoparticles carrying therapeutic agents configured for treating cardiovascular related disorders, methods for synthesizing such sHDL nanoparticles, as well as systems and methods utilizing such sHDL nanoparticles (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutic agents, imaging agents, and/or targeting agents (e.g., in cardiovascular disease diagnosis and/or therapy, etc.))).
    Type: Application
    Filed: May 8, 2023
    Publication date: October 19, 2023
    Inventors: Anna A. Schwendeman, Yuqing Eugene Chen, Yanhong Guo, Jifeng Zhang, Wenmin Yuan, Emily Morin
  • Patent number: 11642419
    Abstract: The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising synthetic HDL (sHDL) nanoparticles carrying therapeutic agents configured for treating cardiovascular related disorders, methods for synthesizing such sHDL nanoparticles, as well as systems and methods utilizing such sHDL nanoparticles (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutic agents, imaging agents, and/or targeting agents (e.g., in cardiovascular disease diagnosis and/or therapy, etc.))).
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: May 9, 2023
    Assignee: The Regents of the University of Michigan
    Inventors: Anna A. Schwendeman, Yuqing Eugene Chen, Yanhong Guo, Jifeng Zhang, Wenmin Yuan, Emily Morin
  • Publication number: 20220175926
    Abstract: Reactive oxygen species (ROS) generated with noninvasive ultrasound and sonosensitizers, potently synergize with selected immunomodulators to hyperactivate dendritic cells and macrophages at desired locations and times within the body. Together with the tumor antigens provided by dying/dead tumor cells, these signals can result in activation of adaptive immune responses. This approach is useful for eliciting T cell responses within tumors present in any tissue of the body.
    Type: Application
    Filed: March 30, 2020
    Publication date: June 9, 2022
    Inventors: Jeffrey M. KARP, Rui KUAI, Jun XU, Wenmin YUAN, Dania ZHIVAKI, Jonathan C. KAGAN, Andrew BELLINGER
  • Publication number: 20210299081
    Abstract: The invention provides solid, self-emulsifying compositions for oral administration. The compositions can comprise a population of particles comprising a cannabinoid or a terpene, a surfactant, and a solid carrier. The invention also encompasses methods for the preparation and use thereof.
    Type: Application
    Filed: March 24, 2021
    Publication date: September 30, 2021
    Inventors: Wenmin Yuan, Oren Levy, Tuna Yucel
  • Publication number: 20200138072
    Abstract: The invention is directed to a nanoprecipitate comprising a cannabinoid or a terpene, or combination thereof, a process of preparing the nanoprecipitate, and oral formulations comprising the nanoprecipitate, including beverage additives and edibles.
    Type: Application
    Filed: November 1, 2019
    Publication date: May 7, 2020
    Inventors: Tuna Yucel, Marvin J. Rudolph, Stephen E. Zale, Nicholas J. Boylan, Scott S. Finnance, Wenmin Yuan, Gregory Fahs, Oren Levy
  • Publication number: 20180250419
    Abstract: The present invention relates to nanoparticles complexed with therapeutic agents configured for treating cardiovascular related disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising synthetic HDL (sHDL) nanoparticles carrying therapeutic agents configured for treating cardiovascular related disorders, methods for synthesizing such sHDL nanoparticles, as well as systems and methods utilizing such sHDL nanoparticles (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutic agents, imaging agents, and/or targeting agents (e.g., in cardiovascular disease diagnosis and/or therapy, etc.))).
    Type: Application
    Filed: March 25, 2016
    Publication date: September 6, 2018
    Inventors: Anna A. Schwendeman, Yuqing Eugene Chen, Yanhong Guo, Jifeng Zhang, Wenmin Yuan, Emily Morin