Abstract: The invention presents a method for predicting volatile organic compounds (VOCs) adsorption capacity via filling adsorption, in the domain of exhaust gas treatment. Utilizing two or more porous materials with concentrated pore size distributions as model adsorption materials, it identifies the critical pore size for filling adsorption under specific conditions. Filling adsorption operates via volume filling, linking adsorption capacity to density and pore volume. Conversely, non-filling adsorption relies on surface covering mechanisms, correlating adsorption capacity with specific surface area. By establishing a linear equation using pore volume and specific surface area, solved with known model material parameters, it accommodates pore size variation and pressure influence on adsorption capacity. This equation predicts VOCs adsorption capacity and isotherms based on the adsorption material's pore structure.

Abstract: The present application provides a catalyst for copolymerization of ethylene and methyl methacrylate and an application thereof. The catalyst includes a main catalyst, and the main catalyst is obtained by compounding a compound of formula (I) and a compound of formula (II); a mole ratio of the compound of formula (I) to the compound of formula (II) is (1:49) to (49:1). The catalyst has an excellent catalytic activity, and a copolymer of ethylene and methyl methacrylate with a high molecular weight can be obtained, with a weight average molecular weight of not less than 1×105 g/mol.

Abstract: The present application discloses a method for processing a file read-write service. The method includes: in response to receiving a read-write service of a file, determining, based on a file serial number, whether a cache handle of the file is present in an index container; in response to the cache handle of the file not being present in the index container, opening, based on the read-write service, a corresponding handle of the file; encapsulating a flag and a pointer of the corresponding handle and the file serial number so as to obtain a cache handle of the file; adding the cache handle of the file into the index container and a first queue; processing the read-write service by using the corresponding handle of the file; and in response to completion of processing the read-write service, moving the cache handle of the file from the first queue to a second queue.

Abstract: The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in particular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the description.

Abstract: A machine learning model training method is applied to a first client, a plurality of clients are communicatively connected to a server, the server stores a plurality of modules, and the plurality of modules are configured to construct at least two machine learning models. The method includes: obtaining a first machine learning model, where at least one first machine learning model is selected based on a data feature of a first training data set stored in the first client; performing a training operation on the at least one first machine learning model by using the first data set, to obtain at least one trained first machine learning model; and sending at least one updated module to the server, where the updated module is used by the server to update weight parameters of the stored modules.

Abstract: Provided are a method and device for local random readahead of a file in a distributed file system. The method includes: creating a readahead structure pointer in an operation handle of a file; in response to reading of the file, accessing and updating information in the readahead structure pointer, and determining whether the reading is local random reading; and performing readahead in a case where the reading is local random reading, the number of instances of continuous reading in the updated information is greater than 1, and a current reading position is greater than or equal to a readahead trigger position in the updated information.

Abstract: A pre-read data caching method and apparatus, a device, and a storage medium, the method including: receiving a read command for a target file; if determining that there is target pre-read data of the target file in a pre-read queue, then moving the pre-read data from the pre-read queue into a secondary cache queue; reading the target pre-read data in the secondary cache queue; and, after reading is complete, moving the target pre-read data from the secondary cache queue into a reset queue, the invalidation priority level of the pre-read queue being the lowest.

Abstract: A pre-read data caching method and apparatus, a device, and a storage medium, the method including: receiving a read command for a target file; if determining that there is target pre-read data of the target file in a pre-read queue, then moving the pre-read data from the pre-read queue into a secondary cache queue; reading the target pre-read data in the secondary cache queue; and, after reading is complete, moving the target pre-read data from the secondary cache queue into a reset queue, the invalidation priority level of the pre-read queue being the lowest.

Abstract: Embodiments of the disclosure include methods and compositions related to immunotherapy that targets glypican-3. In particular embodiments, immune cells engineered to comprise a chimeric antigen receptor that targets glypican-3 are contemplated, and uses thereof. In particular embodiments, medical conditions that are associated with glypican-3 expression or an overexpression of glypican-3 are treated with GPC3 CARs.

Abstract: The invention relates to a catalyst for the catalytic esterification and acylation reaction.

Abstract: The invention relates to an application of organic framework porous solid acid.