Abstract: The disclosure discloses a method, an apparatus, a storage medium, a device and a program product for image processing. The method includes: obtaining a prompt word and a scene mesh, wherein the prompt word is text information provided by a user and represents a scene style, and the scene mesh is a three-dimensional mesh with a real texture generated based on a real scene reconstruction; generating a stylized panoramic texture map at the center position of the scene mesh based on the prompt word; projecting the texture of the stylized panoramic texture map to the visible area of the scene mesh to obtain a first stylized mesh texture mapping; and performing a spatial texture propagation processing on the first stylized mesh texture mapping to fill the non-visible area of the scene mesh to obtain a second stylized mesh texture mapping.

Abstract: The present invention relates to the field of coal mine concealed fire zone detection, in particular to a coal spontaneous combustion downhole detection system and method based on a self-potential method. The coal spontaneous combustion downhole detection system comprises a self-potential detection apparatus and a self-potential processing apparatus; the self-potential detection apparatus comprises measuring electrodes, a reference electrode and metal anchor rods; the measuring electrodes are arranged on a top plate of a goaf roadway, are fixed to the metal anchor rods, and are in wireless connection with the reference electrode through the metal anchor rods; the self-potential processing apparatus comprises a data processing sensor for processing potential data and an imaging sensor for converting data into images; and the measuring electrodes and the reference electrode are in wireless connection with the data processing sensor.

Abstract: A backlight module includes a light-emitting substrate, at least one chip-on-film and a backplane. The light-emitting substrate includes a signal line group and a plurality of light-emitting units, and the plurality of light-emitting units are electrically connected to the signal line group. The at least one chip-on-film is arranged on a non-light exit side of the light-emitting substrate, and electrically connected to the signal line group. The backplane is disposed on the non-light exit side of the light-emitting substrate, and the at least one chip-on-film is located between the backplane and the light-emitting substrate. The backplane is provided with a groove therein, a notch of the groove faces the light-emitting substrate, and at least portion of a chip-on-film film of the at least one chip-on-film is disposed in the groove.

Abstract: Disclosed is a monoclonal antibody that specifically binds CD3, or an antigen binding fragment thereof, and its use in treating or alleviating an inflammatory disease, an autoimmune disease, or transplantation rejection.

Abstract: Disclosed is a monoclonal antibody that specifically binds BCMA, or an antigen binding fragment thereof, and its use in treating cancers such as multiple myeloma. Also disclosed is a monoclonal antibody that specifically binds CD3, or an antigen binding fragment thereof, and its use in treating or alleviating an inflammatory disease, an autoimmune disease, or transplantation rejection. Further disclosed is an anti-BCMA/CD3 bispecific antibody, and its use in treating diseases such as cancers.

Abstract: Disclosed is a multi-specific antibody targeting CD40 and PD-L1, as well as its use in the treatment of diseases such as tumors.

Abstract: Disclosed is a molecule, e.g., a single-domain antibody, or a heavy chain only antibody, that specifically binds human PD-LI, and its use in treating diseases such as tumors.

Abstract: Disclosed is a monoclonal antibody that specifically binds BCMA, or an antigen binding fragment thereof, and its use in treating cancers such as multiple myeloma. Also disclosed is a monoclonal antibody that specifically binds CD3, or an antigen binding fragment thereof, and its use in treating or alleviating an inflammatory disease, an autoimmune disease, or transplantation rejection. Further disclosed is an anti-BCMA/CD3 bispecific antibody, and its use in treating diseases such as cancers.

Abstract: Disclosed is a bispecific molecule specifically binding TIGIT and VEGF, and its use in treatment of e.g., tumors.

Abstract: Disclosed is a single chain fragment variable (scFv), comprising a heavy chain variable region, a linker and a ? light chain variable region, wherein the ? light chain variable region is engineered to comprise leucin (L), threonine (T) and alanine (A) at Position 104 to 106 according to the Kabat numbering scheme.

Abstract: A method of re-routing an off route vehicle is described. A transportation system provides a route from an origin to a destination to a client device associated with a driver of the route. The transportation system receives location data from the client device associated with the driver and calculates one or more error values based on the location data. The transportation system provides a re-route to the client device based on determining that the one or more error values are greater than a threshold value.

Abstract: The invention relates to a tube (100) with a hollow cylindrical elastic base structure (102) for insertion into a blood vessel (200) of a vascular system (202). The tube (100) comprises an outer anisotropic surface structure (104) comprising a geometrical anisotropy between a direction circumferential to the tube and a direction longitudinal to the tube (100). The anisotropic surface structure (104) is configured for establishing an anisotropic friction between the anisotropic surface structure (104) and an inner surface of the blood vessel (200). The anisotropic friction results in a surface propulsion of the tube (100), when the tube (100) is rotated around a central longitudinal body axis (106) of the tube (100). The tube (100) further comprises a magnetic material (108) distributed circumferentially around the tube (100) and configured for establishing within an external magnetic field a rotation of the tube (100) around the central longitudinal body axis (106) of the tube (100).

Abstract: The present invention relates to a method of fabricating magnetic deformable machines comprising heterogeneous voxels, as well as to a deformable 3D magnetic machine, the magnetic machine having a size of less than 10000 mm, the magnetic machine comprising a plurality of voxels of which at least some are magnetic, with at least some of the voxels having a Young's modulus of less than 500 MPa, the plurality of voxels being bonded one to another with a bonding agent, wherein each voxel is of predefined shape, size, has predefined magnetic properties and predefined material properties.

Abstract: A microfluidic chip device based on a magnetic field-controlled fluorescently labeled cell sorting method and a use method are disclosed. The microfluidic chip comprises a sample channel, two sheath fluid channels, a first fluorescence detection area, a second fluorescence detection area, a magnetic field control system, a magnetic field-controlled cell sorting area, a target cell channel, and a waste fluid channel. Based on fluorescence signals labeled on the cells, the FACS system is combined with a magnetic field-controlled sorting system to achieve automated cell sorting, which not only miniaturizes and automates the sorting detection integration, but also has the advantages of easy and economical operation. The device sorts both a large number of cell samples and a small number of cell samples, thus overcoming the defects of a flow cytometer.

Abstract: An isolated monoclonal antibody, or an antigen-binding portion thereof, that specifically binds human PD0-L1. A nucleic acid molecule encoding the antibody or antigen-binding portion thereof, an expression vector, a host cell and a method for expressing the antibody or antigen-binding portion thereof are also provided. The present disclosure further provides an immuneconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody or antigen-binding portion thereof, as well as a treatment method using the antibody or antigen-binding portion thereof.

Abstract: An isolated monoclonal antibody, or an antigen-binding portion thereof, that specifically binds human TIGIT. A nucleic acid molecule encoding the antibody or antigen-binding portion thereof, an expression vector, a host cell and a method for expressing the antibody or antigen-binding portion thereof are also provided. The present disclosure further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody or antigen-binding portion thereof, as well as a treatment method using the antibody or antigen-binding portion thereof.

Abstract: An isolated monoclonal antibody, or an antigen-binding portion thereof, that specifically binds human PD-L1. A nucleic acid molecule encoding the antibody or antigen-binding portion thereof, an expression vector, a host cell and a method for expressing the antibody or antigen-binding portion thereof are also provided. The present disclosure further provides an immuneconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody or antigen-binding portion thereof, as well as a treatment method using the antibody or antigen-binding portion thereof.

Abstract: A coordination server receives a request from a client device of a rider for transportation from a first location. The coordination server identifies a frequent spot based on the first location. The frequent spot is associated with a particular location and represents a plurality of historic first locations within a threshold distance from the frequent spot. The coordination server identifies a closest road segment with respect to the frequent spot. The closest road segment is a road segment of a plurality of road segments of an electronic map representing a geographic area around the first location. The coordination server determines a pickup side of the closest road segment based on the first location and the closest road segment. The coordination server sends, to a client device of a driver, a route to the first location such that the driver arrives on the pickup side of the closest road segment.

Abstract: An isolated monoclonal antibody or an antigen-binding portion thereof that specifically binds human OX40. A nucleic acid molecule encoding the antibody, an expression vector, a host cell and a method for expressing the antibody are also provided. The present invention further provides an immunoconjugate, a bispecific molecule, a chimeric antigen receptor, an oncolytic virus and a pharmaceutical composition comprising the antibody, as well as a treatment method using an anti-OX40 antibody of the invention.

Abstract: The present invention relates to a method of actuating a shape changeable member of actuatable material. The invention further relates to a shape changeable member and to a system comprising such a shape changeable member and a magnetic field apparatus.