Abstract: Embodiments of the present disclosure provide a plasma-enhanced atomic layer deposition apparatus and a method thereof. The apparatus includes a precursor supply device communicating with gas inlet structures of two process chambers and configured to selectively provide a precursor or a purge gas to at least one of the two process chambers, a reaction gas supply device communicating with the gas inlet structures of the two process chambers and configured to selectively provide a reaction gas to at least one of the two process chambers, a radio frequency device connected to the two process chambers and configured to selectively output radio frequency power to at least one of the two process chambers, and a pressure adjustment device communicating with exhaust openings of the two process chambers and configured to independently control chamber pressures of the two process chambers.

Abstract: Disclosed are a tricyclic derivative and a preparation method therefor and an application thereof. Specifically, disclosed are a compound shown in formula (I) and an optical isomer thereof or a pharmaceutically acceptable salt thereof, and an application of the compound as an Autotaxin inhibitor.

Abstract: The present application describes a polycyclic compound represented by general formula (I) as a Cbl-b inhibitor, or a stereoisomer or pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the compound of general formula (I) or the stereoisomer or pharmaceutically acceptable salt thereof, and a use of the compound of general formula (I) or the stereoisomer or pharmaceutically acceptable salt thereof, or the pharmaceutical composition in the prevention or treatment of diseases or conditions mediated by Cbl-b.

Abstract: A heat pipe includes a pipe body having a sealed cavity. A heat transfer medium and a capillary structure are disposed in the sealed cavity. The pipe body includes a first additional pipe section and a main pipe section including an evaporation section, a heat insulation section, and a condensation section. The first additional pipe section, where a first additional cavity is disposed, is connected to an end part of the evaporation section. The first additional cavity is used to accommodate all or a part of the heat transfer medium when the heat pipe is vertically placed and the first additional pipe section is located below a gravity direction, and when the heat pipe is mounted on a heat dissipation device that requires heat dissipation, the first additional pipe section is not in contact with a heat emitting component of the heat dissipation device.

Abstract: The present invention provides a benzoheterocycle substituted tetrahydroisoquinoline compound, and in particular, relates to a compound shown in formula (I) and a pharmaceutically acceptable salt thereof, and the compound for the treatment of chronic kidney disease.