Patents by Inventor Wensheng Lang

Wensheng Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell based screening assays for the triglyceride synthesis pathway
    Patent number: 9012159
    Abstract: A method for identifying a compound which modulates the activity of acyl-coA: diacylglycerol acyltransferase comprises the steps of contacting a stable isotope labeled fatty acid with cells in either presence or absence of the compound, extracting the cells with isopropyl alcohol, and determining the level of a stable isotope labeled triglyceride in the presence or absence of the compound; wherein a change in the level of the stable isotope labeled triglyceride indicates that the compound modulates the DGAT activity.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: April 21, 2015
    Assignee: Janssen Research & Development, LLC
    Inventors: Jian-Shen Qi, Wensheng Lang, Margery A. Connelly
  • CELL BASED ASSAYS FOR THE TRIGLYCERIDE SYNTHESIS PATHWAY
    Publication number: 20100196930
    Abstract: A method for identifying a compound which modulates the activity of acyl-coA: diacylglycerol acyltransferase comprises the steps of contacting a stable isotope labeled fatty acid with cells in either presence or absence of the compound, extracting the cells with isopropyl alcohol, and determining the level of a stable isotope labeled triglyceride in the presence or absence of the compound; wherein a change in the level of the stable isotope labeled triglyceride indicates that the compound modulates the DGAT activity.
    Type: Application
    Filed: January 7, 2010
    Publication date: August 5, 2010
    Inventors: Jian-Shen Qi, Wensheng Lang, Margery A. Connelly