Patents by Inventor Wenxin Dong

Wenxin Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR ENHANCING IMMUNE RESPONSE
    Publication number: 20230233677
    Abstract: A modified immune cell that has attenuated expression and/or activity of YTH N6-Methyladenosine RNA Binding Protein 2 (YTHDF2), and enhanced anti-tumor activity. A composition for stimulating T cell-mediated immune response to a cancer cell and/or a tumor antigen, including an agent capable of attenuating the expression and/or activity of YTHDF2, and a pharmaceutically acceptable excipient. A composition for treating cancer, comprising an agent capable of attenuating the expression and/or activity of YTHDF2. A method for activating an immune cell. A method for generating an immune cell. A method for treating a disease, disorder or condition associated with an expression of a tumor antigen in a subject in need thereof. A method for stimulating a T cell-mediated immune response to a cancer cell and/or a tumor antigen in a subject in need thereof.
    Type: Application
    Filed: June 8, 2021
    Publication date: July 27, 2023
    Applicant: HANGZHOU LEADING EDGE PHARMACEUTICAL LTD.
    Inventors: Meng XU, Xuanming YANG, Wenxin DONG
  • Nanometer self-locking bentonite film-forming agent, method for preparing the same, and film-forming drilling fluid
    Patent number: 11639460
    Abstract: The present application discloses a nanometer self-locking bentonite film-forming agent, a method for preparing the same, and a film-forming drilling fluid.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: May 2, 2023
    Assignees: Southwest Petroleum University, Chongqing University, Sichuan Xinlin New Material Technology Co., Ltd.
    Inventors: Wenxin Dong, Xiaolin Pu, Jinyang Fan, Wenhao Liu, Siyi Chen, Hanyi Wang, Deyi Jiang, Yi Cao, Jianjun Chen, Yao Ge, Jinsheng Sun, Wei Chen, Tao Han, Jingwen Xiao
  • Thermosensitive self-plugging bentonite and preparation method thereof and water-based drilling fluid
    Patent number: 10920123
    Abstract: The present disclosure relates to a thermosensitive self-plugging bentonite, a preparation method thereof, and a water-based drilling fluid.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: February 16, 2021
    Assignee: SOUTHWEST PETROLEUM UNIVERSITY
    Inventors: Xiaolin Pu, Wenxin Dong
  • Thermosensitive Self-plugging Bentonite and Preparation Method Thereof and Water-based Drilling Fluid
    Publication number: 20200283673
    Abstract: The present disclosure relates to a thermosensitive self-plugging bentonite, a preparation method thereof, and a water-based drilling fluid.
    Type: Application
    Filed: March 3, 2020
    Publication date: September 10, 2020
    Inventors: Xiaolin PU, Wenxin DONG
  • Aralkyl-alcohol peiperazine derivatives and their uses as antidepressant
    Patent number: 7576086
    Abstract: Aryl alkanol piperazine derivatives of the formula and pharmaceutical compositions comprising the same. Also disclosed are methods for treating depression using the pharmaceutical composition. Compounds of the invention have excellent dual inhibitory actions to the uptake of the mono-amines neurotransmitter, good antidepressant activities and minor side effects.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: August 18, 2009
    Assignee: Shanghai Institute of Pharmaceutical Industry
    Inventors: Jianqi Li, Liying Huang, Wenxin Dong, Xia Ge, Chengjin Shi
  • Aralkyl-alcohol peiperazine derivatives adn their uses as antidepressant
    Publication number: 20050267121
    Abstract: Aryl alkanol piperazine derivatives of the formula and pharmaceutical compositions comprising the same. Also disclosed are methods for treating depression using the pharmaceutical compositon. Compounds of the invention have excellent dual inhibitory actions to the uptake of the mono-amines neurotransmitter, good antidepressant activities and minor side effects.
    Type: Application
    Filed: April 16, 2003
    Publication date: December 1, 2005
    Applicant: Shanghai Institute of Pharmaceutical Industry
    Inventors: Jianqi Li, Liying Huang, Wenxin Dong, Xia Ge, Chengjin Shi