Abstract: The present invention discloses a method and apparatus for brain perfusion magnetic resonance imaging (MRI) technique with the removal of cerebrospinal fluid (CSF) pixels. This invention utilizes a CSF/brain-contrast-enhanced image, wherein the CSF/brain-contrast-enhanced image is defined as the signal difference between CSF and brain matter divided by a standard deviation of air background random noise is larger than 3, acquired from the subject's brain, and applies a segmentation technique to remove the CSF pixels. After removing the CSF pixels on parametric images, the extent of brain tissue with delayed perfusion can be better identified. By using a good region of interest enclosing the correct delayed-perfusion region, the measurement on the tissue volume and perfusion parameters would be more accurate than the area contaminated by CSF pixels.

Abstract: The present invention discloses a method and apparatus for brain perfusion magnetic resonance imaging (MRI) technique with the removal of cerebrospinal fluid (CSF) pixels. This invention utilizes a CSF/brain-contrast-enhanced image, wherein the CSF/brain-contrast-enhanced image is defined as the signal difference between CSF and brain matter divided by a standard deviation of air background random noise is larger than 3, acquired from the subject's brain, and applies a segmentation technique to remove the CSF pixels. After removing the CSF pixels on parametric images, the extent of brain tissue with delayed perfusion can be better identified. By using a good region of interest enclosing the correct delayed-perfusion region, the measurement on the tissue volume and perfusion parameters would be more accurate than the area contaminated by CSF pixels.