Abstract: In one embodiment, a disintegration or dissolution testing apparatus (100) including at least one area for a compartment (205) to hold a dosage form during disintegration testing, and at least one light emitter (302) and at least one light detector (303) arranged around each of the areas so as to face the area. The light detector (303) is adapted to provide, when a compartment (205) is disposed within the area a signal indicative of the amount of detected light provided by the light emitter (302). In another embodiment, a bottom flange (202) for disintegration test apparatus (100) is encapsulated in a material that (i) permits the bottom flange (202) to be immersed in a liquid medium during disintegration testing without the liquid contacting any of the light emitters (302) or detectors (303), and (ii) permits light from the emitter (302) to pass through the material and be received by the light detector (303).

Abstract: The present invention has provided a method for live broadcasting in distributed network and means for the same. Wherein the method mainly comprises steps of: tracker servers receive the status report information from the program source connected to the tracker server; generates the status information of the program source based on said status report information; sends status information of the program source to the information synchronization means.

Abstract: In one embodiment, a modular dissolution-testing apparatus has a base unit adapted to hold and control operation of between one and eight dissolution-testing modules. The base unit has a programmable controller and a color touch screen for user interface with the controller and the modules. Each module includes a vessel for holding a solution of a dosage form dissolving in a solvent, an agitator apparatus for stirring the solution, and a motor to power—via a multi-motion assembly and a stirring shaft—stirring by, lifting of, and lowering of, the apparatus. Each module has a vessel heater and a temperature sensor, both communicatively connected to the controller for heating and regulating the temperature of the vessel contents. Each module is independently controllable by the controller, where control includes manually (by a user) or programmatically setting stirring speed, lifting and lowering apparatus, and starting and stopping stirring and heating.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: An automated music displaying system includes a displaying device, a main processing module electrically connecting to the displaying device for driving the displaying device to display a predetermined page of a music sheet in electronic format, and a stepping actuator electrically connecting to the main processing module, wherein when the stepping actuator is actuated, the stepping actuator is arranged to send a signal to the main processing module for driving the displaying device to change a display of a page of sheet music.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: In one embodiment, a modular dissolution-testing apparatus has a base unit adapted to hold and control operation of between one and eight dissolution-testing modules. The base unit has a programmable controller and a color touch screen for user interface with the controller and the modules. Each module includes a vessel for holding a solution of a dosage form dissolving in a solvent, an agitator apparatus for stifling the solution, and a motor to power—via a multi-motion assembly and a stifling shaft—stifling by, lifting of, and lowering of, the apparatus. Each module has a vessel heater and a temperature sensor, both communicatively connected to the controller for heating and regulating the temperature of the vessel contents. Each module is independently controllable by the controller, where control includes manually (by a user) or programmatically setting stifling speed, lifting and lowering apparatus, and starting and stopping stirring and heating.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: A device, method and system are provided to continuously store and analyze single or multi-lead ambulatory ECG signals. Each ECG device is self-contained, wire-free, reusable and capable of non-invasive continuous recording, analyzing and indexing of ECG data independently. A pair of snap connectors on the device body attaches the device to standard ECG electrodes to minimize noise caused by the wires. Each device contains a real-time clock to link the ECG data and a detected cardiac event with actual date and time. The device contains a USB port to upload the data to a host system. Multiple such devices are wearable by a patient to form a multi-lead ECG system. There is provided a method to continuously record and analyze ECG data using a self-contained, wire-free ECG device or multiple such devices; and further a method to synchronize the ECG data in multiple devices to realize multi-lead ECG recording.

Abstract: The present invention relates to method and device for file transmission based on multiple protocols. According to an embodiment of the present invention, there is provided a method in a user node of downloading files, comprising the steps of: A. intercepting a request message from an application functional entity, for requesting a file based on a first protocol; B. downloading said file at least based on a second protocol; C. providing said file to said application functional entity. With the method, software, storage media provided in the present invention, faster download speed could be obtained when the client downloads files from the network base on the first protocol, compared with that obtained in the traditional C/S mode, therefore the user experience is improved.

Abstract: The present invention has provided a method for live broadcasting in distributed network and means for the same. Wherein the method mainly comprises steps of: tracker servers receive the status report information from the program source connected to the tracker server; generates the status information of the program source based on said status report information; sends status information of the program source to the information synchronization means.

Abstract: Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.

Abstract: A method of free radical polymerization and for cleaving a thio group from the resulting polymer is provided. The method comprises forming a mixture of one or more monomers, at least one free radical source and a control agent, wherein the control agent comprises a thio moiety. The mixture is polymerized, and the resulting polymer is mixed with a free radical source, and optionally an addition fragmentation agent under cleavage conditions. The thio moiety on the polymer is replaced with a group of interest.

Abstract: Control agents that have a nitrogen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers. These control agents provide superior properties for control of the polymerization and/or the properties of the polymers obtained and/or the monomers that may be polymerized. In some embodiments, a bulky group is pendant off the activated thiocarbonyl portion of the control agents. Multifunctional control agents provide the opportunity for a variety of structurally unique polymers, including block copolymers, stars and hyper-branched polymers.

Abstract: Control agents that have a nitrogen-nitrogen bond covalently bonded to a thiocarbonyl moiety are provided for living-type free radical polymerization of a wide variety of monomers. These control agents provide superior properties for control of the polymerization and/or the properties of the polymers obtained and/or the monomers that may be polymerized. In some embodiments, a bulky group is pendant off the activated thiocarbonyl portion of the control agents. Multifunctional control agents provide the opportunity for a variety of structurally unique polymers, including block copolymers, stars and hyper-branched polymers.

Abstract: A method of free radical polymerization and for cleaving a thio group from the resulting polymer is provided. The method comprises forming a mixture of one or more monomers, at least one free radical source and a control agent, wherein the control agent comprises a thio moiety. The mixture is polymerized, and the resulting polymer is mixed with a free radical source, and optionally an addition fragmentation agent under cleavage conditions. The thio moiety on the polymer is replaced with a group of interest.