Patents by Inventor Wenyuan Qian

Wenyuan Qian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazine derivatives and methods of use
    Patent number: 7393852
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: July 1, 2008
    Assignee: Amgen Inc.
    Inventors: Jian J. Chen, Ben C. Askew, Kaustav Biswas, Jennifer N. Chau, Derin C. D'Amico, Scott Harried, Thomas Nguyen, Wenyuan Qian, Jiawang Zhu, Christopher H. Fotsch, Aiwen Li, Qingyian Liu, Nobuku Nishimura, Tanya Peterkin, Babak Riahi, Chester Chenguang Yuan, Nianhe Han, Rana Nomak, Kevin Yang
  • Glycine transporter-1 inhibitors
    Publication number: 20080004289
    Abstract: The present invention provides compounds that are glycine transporter 1 (hereinafter referred to as GlyT-1) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of GlyT1 such as cognitive disorders associated with Schizophrenia, ADHD (attention deficit hyperactivity disorder), MCI (mild cognitive impairment), and the like. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
    Type: Application
    Filed: June 26, 2007
    Publication date: January 3, 2008
    Inventors: Stephen Hitchcock, Albert Amegadzie, Wenyuan Qian, Xiaoyang Xia, Scott Harried
  • Substituted sulfones and methods of use
    Publication number: 20060111347
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: October 5, 2005
    Publication date: May 25, 2006
    Applicant: AMGEN INC.
    Inventors: Benny Askew, Toshihiro Aya, Kaustav Biswas, Jian Chen, Jason Human, Wenyuan Qian
  • Triazoles and methods of use
    Publication number: 20060100213
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: October 11, 2005
    Publication date: May 11, 2006
    Applicant: Amgen Inc.
    Inventors: Toshihiro Aya, Guolin Cai, Jian Chen, Derin D'Amico, Thomas Nguyen, Wenyuan Qian
  • 1,2,3,4-Tetrahydropyrazin-2-yl acetamides and methods of use
    Publication number: 20060025400
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 2, 2006
    Inventors: Benny Askew, Toshihiro Aya, Kaustav Biswas, Guolin Cai, Jian Chen, Nianhe Han, Qingyian Liu, Thomas Nguyen, Nobuko Nishimura, Rana Nomak, Tanya Peterkin, Wenyuan Qian, Kevin Yang, Chester Yuan, Jiawang Zhu, Derin D' Amico, Jason Human, Qi Huang
  • Compounds and methods of use
    Publication number: 20050124654
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: April 12, 2004
    Publication date: June 9, 2005
    Inventors: Robert Groneberg, Bonny Askew, Derin D'Amico, James Zhan, Andras Toro, Youngboo Kim, David Mareska, Nianhe Han, Christopher Fotsch, Qingyian Liu, Babak Riahi, Kevin Yang, Aiwen Li, Chester Yuan, Kaustav Biswas, Scott Harried, Thomas Nguyen, Wenyuan Qian, Jian Chen, Rana Nomak
  • Piperazine derivatives and methods of use
    Publication number: 20050014749
    Abstract: Selected compounds are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation, and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
    Type: Application
    Filed: June 21, 2004
    Publication date: January 20, 2005
    Inventors: Jian Chen, Ben Askew, Kaustav Biswas, Jennifer Chau, Derin D'Amico, Scott Harried, Thomas Nguyen, Wenyuan Qian, Jiawang Zhu, Christopher Fotsch, Aiwen Li, Qingyian Liu, Nobuku Nishimura, Tanya Peterkin, Babak Riahi, Chester Yuan, Nianhe Han, Rana Nomak, Kevin Yang