Patents by Inventor Wera COLLISI

Wera COLLISI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted cytotoxic ratjadone derivatives and conjugates thereof
    Patent number: 11236059
    Abstract: The present invention is directed to novel natural product-derived ratjadone-based compounds useful as payloads (or toxins) in drug-conjugates constructs with cell target binding moieties (CTBM) and payload-linker compounds useful in connection with drug conjugates. The present invention further relates to new ratjadone compositions including the aforementioned payloads, payload-linkers and drug conjugates, and methods for using these payloads, payload-linkers and drug conjugates, to treat pathological conditions including cancer, inflammatory and infectious diseases.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: February 1, 2022
    Assignee: HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH
    Inventors: Philipp Klahn, Mark Broenstrup, Verena Fetz, Wera Collisi, Katrin I Mohr, Stephan Huettel, Werner Tegge
  • TARGETED CYTOTOXIC RATJADONE DERIVATIVES AND CONJUGATES THEREOF
    Publication number: 20200239426
    Abstract: The present invention is directed to novel natural product-derived ratjadone-based compounds useful as payloads (or toxins) in drug-conjugates constructs with cell target binding moieties (CTBM) and payload-linker compounds useful in connection with drug conjugates. The present invention further relates to new ratjadone compositions including the aforementioned payloads, payload-linkers and drug conjugates, and methods for using these payloads, payload-linkers and drug conjugates, to treat pathological conditions including cancer, inflammatory and infectious diseases.
    Type: Application
    Filed: August 8, 2018
    Publication date: July 30, 2020
    Inventors: Philipp KLAHN, Mark BROENSTRUP, Verena FETZ, Wera COLLISI, Katrin I MOHR, Stephan HUETTEL, Werner TEGGE