Abstract: The present disclosure relates to a biocompatible polymer composition for an article comprising a surface intended to contact blood, tissue, skin, epithelial layers, wounds, cells in culture fluids, body fluids, dialysis fluids, therapeutic fluids, or mixtures thereof for removal or infusion. The invention also relates to a method for the preparation of an article comprising the biocompatible polymer composition and a use thereof.

Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, an infusion line (16) with an infusion pump (17) and a programmed controller (14) for calculating a maximum infusion rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.

Abstract: This invention relates to a housing element (10) for a control unit housing (1) comprising one or more first edge sections (11) for contact with a second edge section (21) of a second housing element (20) allocated to the control unit housing (1) with the intermediate layer of the sealant (2) that is able to be hardened with the assistance of air moisture, whereas at least one of the first edge sections (11) features at least one recess (13) for the communication of the sealant (2) in the state of contact of the housing elements (10, 20) with air containing the air moisture.

Abstract: A device for applying a lock solution in a catheter or other access system comprises a syringe (302) having an expulsion arrangement (305, 311) for expelling the lock solution from the device, said expulsion arrangement including a plunger (305) arranged in a housing (304), further comprising a sterile connector (303) for connecting the syringe (302) to the catheter. The connector (303) is arranged to engage a tip (307) of the expulsion arrangement (305, 311) tightly when the syringe (302) is inserted in the connector (303). The connector (303) is arranged to prevent the tip (307) of the expulsion arrangement (305, 311) from entering the catheter. The tip (307) is frangible. A method of applying a lock solution in a catheter or other access system is also disclosed.

Abstract: The invention relates to an operating element for operating a device, especially an X-ray apparatus, in the form of a touch screen, said touch screen has a touch sensitive screen surface an is provided with a calibration routine for calibrating the touch screen. The invention is characterized in that during a start-up phase of the apparatus, the touch screen is configured in such a manner that it can be used as an activation element for activating the calibration routine.

Abstract: The present invention relates to a method of treating anemia especially in an EPO resistant hemodialysis patient, comprising hemodialysis with a high cut-off dialysis membrane, wherein the hemodialysis membrane is characterized in that it has a molecular weight cut-off in water, based on dextran sieving coefficients, of between 90 and 200 kD and a molecular weight retention onset in water, based on dextran sieving coefficients, of between 10 and 20 kD, and a ?MW of between 90 and 170 kD. The invention further relates to a high cut-off hemodialysis membrane for the treatment of anemia in hemodialysis patients, especially EPO resistant hemodialysis patients.

Abstract: A method for processing at least one surface element wherein at least one layer of a deformable, medium-tight material is respectively attached to each side of the surface element, inserts the surface element and attached deformable layers between at least two molding tool parts and applies a pressure to at least one area of a surface section of the inserted surface element in response to a predetermined shaping temperature by introducing a medium between one of the deformable layers and a first molding tool part. The pressure acts directly against the deformable layer so that the surface element together with the deformable layers is shaped into at least one adjacent cavity of a second molding tool part due to the pressure created. A possibility of molding surface elements, which can currently not be shaped via gas pressure, into complex geometries, namely into spatially bent geometries, is created with this method.

Abstract: A foot pedal module (1) including an enclosure (3), a rotor (11), a foot pedal (15), two springs (17, 19) and a circuit board (33). The enclosure (3) has a trunnion (5), an outer ring (29) and a cover (39) for accommodating and protecting the rotor (11). The rotor (11) is linked with a bushing (7), a tappet, a lever (13), two haptic springs (17, 19), two damping elements (21, 23) and a driving element (27). The circuit board (33) carries an inductor array (25) which are designed as flat coils and located opposite the damping elements (21, 23). The foot pedal (15) is linked to the lever (13) and bushing (7) by a ball joint (35) and a socket (27).

Abstract: A connector for electrical and mechanical interconnection of first and second mechanically adjacent modules with one another. The first module includes a first electrical connector and an alignment pin and the second module includes a printed circuit board floatingly and displacably mounted on the second module with at least one alignment hole aligned for alignment with the alignment pin of the first module and a second electrical connector aligned for engagement with a corresponding first electrical connector of the first module. During assembly, the alignment pin of the first module engages the alignment hole of the second module and displaces the printed circuit board to align the second electrical connector with the first electrical connector.

Abstract: A connector for electrical and mechanical interconnection of first and second mechanically adjacent modules with one another. The first module includes a first electrical connector and an alignment pin and the second module includes a printed circuit board floatingly and displacably mounted on the second module with at least one alignment hole aligned for alignment with the alignment pin of the first module and a second electrical connector aligned for engagement with a corresponding first electrical connector of the first module. During assembly, the alignment pin of the first module engages the alignment hole of the second module and displaces the printed circuit board to align the second electrical connector with the first electrical connector.

Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, an infusion line (16) with an infusion pump (17) and a programmed controller (14) for calculating a maximum infusion rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.

Abstract: A machine (1) for extracorporeal blood treatment comprises a device (2) for ultrafiltration of a liquid through a semi-permeable membrane (3) of a blood treatment device (4), a first sensor (11) for ultrafiltration rate through the membrane, a second group of sensors (13) for measuring a trans-membrane pressure, and a programmed controller (14) for calculating a maximum ultrafiltration rate as a function of the transmembrane pressure. The machine is suitable for kidney failure treatments, such as hemofiltration and hemodiafiltration. In a relatively short time the machine enables a large quantity of corporeal blood to be removed from the patient.

Abstract: A compressor blade 1 of a gas-turbine engine has a flow-exposed leading edge 2. A component 3, made of wear-resistant material and featuring a higher erosive wear resistance than the base material, is attached to at least part of a length of the leading edge 2 The component 3 forming the flow-exposed leading edge 2 is strip-shaped, has an essentially rectangular cross-section and, with reference to a sectional plane perpendicular to the radial direction, is arranged only on an inflow side of the compressor blade profile in a partial area of a sectional surface of the inflow area.

Abstract: A method for manufacturing a workpiece 1, 2 uses a forming tool 4, 5 having a cavity 3. An embossing element 6 profiled on at least one surface is arranged on at least one surface of the forming tool 4, 5 for producing a surface structure, and with the profile of the embossing tool 6 is imparted to the surface of the workpiece 1, 2 during a forming process.

Abstract: A method of fabricating a superplastically formable strip or a superplastically formable foil from TiAl6V4 with a thickness of no more than 0.9 mm, preferably less than or equal to 0.5 mm, comprises the steps: a) hot rolling a sheet metal made of TiAl6V4; b) thermal pre-treatment of the hot-rolled sheet metal at a temperature between 650 and 850° C.; and c) cold rolling the hot-rolled and thermally pre-treated sheet metal at a forming rate of at least 30%, wherein the forming rate per single pass amounts to between 1 and 15%, to form a strip or a foil with a thickness of no more than 0.9 mm, wherein the cold-rolled strip or the cold-rolled foil is not annealed.

Abstract: A device for applying a lock solution in a catheter or other access system comprises a syringe (302) having an expulsion arrangement (305, 311) for expelling the lock solution from the device, said expulsion arrangement including a plunger (305) arranged in a housing (304), further comprising a sterile connector (303) for connecting the syringe (302) to the catheter. The connector (303) is arranged to engage a tip (307) of the expulsion arrangement (305, 311) tightly when the syringe (302) is inserted in the connector (303). The connector (303) is arranged to prevent the tip (307) of the expulsion arrangement (305, 311) from entering the catheter. The tip (307) is frangible. A method of applying a lock solution in a catheter or other access system is also disclosed.

Abstract: The present invention concerns an implantable access device and a method for preparing the device. According to the invention the device comprises a shape memory base structure with a biological substructure suitable for cell adhesion, cell engraftment and proliferation for use in transferring and transporting fluid mixtures (blood, suspensions, drug formulations, emulsions, cell suspensions) in/into/out of a human or animal body.

Abstract: The present invention concerns a solution and methods to reduce, treat and/or prevent oxidative stress and cell activation. According to the invention the solution gives rise to the following concentrations of constituents within a blood flow of 0.1-18 mM N-acetyl-cysteine, optionally of 0.01-0.21 mM vitamin C, optionally of 2-26 mM gluconic acid and optionally of 0.01-5 mM glutathione. According to the invention the methods comprises adding a solution according to the invention in an extracorporeal setting through the membrane by adding the solution to the dialysis fluid, or by infusion of a solution according to the invention, either by bolus injection, continuous injection or a combination thereof.

Abstract: A foot pedal module (1) including an enclosure (3), a rotor (11), a foot pedal (15), two springs (17, 19) and a circuit board (33). The enclosure (3) has a trunnion (5), an outer ring (29) and a cover (39) for accommodating and protecting the rotor (11). The rotor (11) is linked with a bushing (7), a tappet, a lever (13), two haptic springs (17, 19), two damping elements (21, 23) and a driving element (27). The circuit board (33) carries an inductor array (25) which are designed as flat coils and located opposite the damping elements (21, 23). The foot pedal (15) is linked to the lever (13) and bushing (7) by a ball joint (35) and a socket (27).

Abstract: The present invention concerns an apheresis material or adsorbant and a method for removing, depleting or inactivating MIF (macrophage migration inhibitory factor) from blood, blood plasma, blood serum or other body fluids. The present invention is also concerned with the use of said apheresis material or adsorbant. In order to prepare a novel means and novel method, which can reduce the activity or amount of the mediator for sepsis and septic shock, MIF, in a patient's body fluid in a manner which is more pleasant and tolerable for the patient than prior art means and methods, the invention proposes that the apheresis material or adsorbant comprises a solid carrier material on the surface of which MIF-binding molecules or functional groups are immobilized. The method proposes that the apheresis material or adsorbant be brought into contact extracorporeally with the blood, blood plasma, blood serum or other body fluids.