Patents by Inventor Werner E. G. Müller

Werner E. G. Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biofilm-inhibiting effect and anti-infective activity of -linked aryl isoquinolines and the use thereof
    Patent number: 8173673
    Abstract: Anti-infective and biofilm-inhibiting activities of aryl isoquinoline-derivatives of the general formulae 1 to 3 are described.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: May 8, 2012
    Assignee: Julius-Maximilians-Universitaet Wuerzburg
    Inventors: Gerhard Bringmann, Tanja Gulder, Ute Hentschel, Frank Meyer, Heidrun Moll, Joachim Morschhäuser, Alicia Ponte-Sucre De Vanegas, Wilma Ziebuhr, August Stich, Reto Brun, Werner E. G. Müller, Virima Mudogo
  • Enzymatic synthesis, modification and degradation of silicon(IV)- and other metal(IV)-compounds
    Patent number: 7794992
    Abstract: The present invention relates to the use of recombinant silicatein-? or silicatein-? isolated from natural sources as well as to silicatein-?-fusion proteins as well as silicatein-?-related enzymes for the synthesis, the degradation and for modification of silicon dioxide (condensation products of silicic acid, silicates), silicones and other silicon(IV)- or metal(IV)-compounds, and their technical uses.
    Type: Grant
    Filed: November 9, 2004
    Date of Patent: September 14, 2010
    Assignee: NanotecMARIN GmbH
    Inventors: Werner E. G. Müller, Heiko Schwertner, Heinz C. Schröder
  • Decomposition and modification of silicate and silicone by silase and use of the reversible enzyme
    Patent number: 7229807
    Abstract: Silicatein is an enzyme of silicate-forming organisms used for the synthesis of their silicate scaffold. The present invention relates to the use of highly-expressed and highly active recombinant silicatein, silicatein isolated from natural sources after gene induction as well as silicatein-fusion proteins for the synthesis of amorphous silicon dioxide (silicic acids and silicates), siloxanes as well as modification of these compounds and their technical use.
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: June 12, 2007
    Assignee: Biotechmarin GmbH
    Inventors: Werner E. G. Müller, Heinz Schröder, Anatoli Krasko
  • Silicatein-mediated synthesis of amorphous silicates and siloxanes and use thereof
    Patent number: 7169589
    Abstract: Silicatein is an enzyme of silicate-forming organisms used for the synthesis of their silicate scaffold. The present invention relates to the use of highly-expressed and highly active recombinant silicatein, silicatein isolated from natural sources after gene induction as well as silicatein-fusion proteins for the synthesis of amorphous silicon dioxide (silicic acids and silicates), siloxanes as well as modification of these compounds and their technical use.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: January 30, 2007
    Inventors: Werner E. G. Müller, Heinz C. Schröder, Bernd Lorenz, Anatoli Krasko
  • Production of primmorphs from disassociated cells of sponges and corals
    Patent number: 6664106
    Abstract: This invention relates to the establishment of a novel method of culturing sponge cells, coral cells and cells from other invertebrates in vitro. The cells cultured in vitro, which can be cultured as units similar to aggregates, are referred to as primmorphs. The method makes the following methods possible for the first time, using cells/aggregates/primmorphs from sponges, corals and other invertebrates: Methods (i) of preparing substances which modulate proliferation and DNA synthesis, (ii) of identifying/detecting environmentally harmful substances, (iii) of culturing bacteria and other micro-organisms, (iv) of preparing asexual reproductive bodies that can be used in aquaculture for growing corresponding organisms, (v) of preparing cell libraries, (vi) of optimising the nutritional requirements of the cells/aggregates/primmorphs, and (vii) of identifying substances which modulate telomerase activity in cells/aggregates/primmorphs.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: December 16, 2003
    Inventor: Werner E. G. Müller