Patents by Inventor Werner F. Fleck

Werner F. Fleck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chrysospermins, active peptides from apiocrea chrysosperma having a pharmacological effect and a use thereof
    Patent number: 5432157
    Abstract: The invention relates to the chrysospermin active peptides of the formula IAcPhe-Aib-Ser-Aib-x-Leu-Gln-Gly-Aib-Aib-Ala-Ala-Aib-Pro- y-Aib-Aib-Gln-Trp-ol (SEQ ID NO. 1)in which x and y, independently of each other, denote Aib or Iva, which are synthesized by the fungus Apiocrea chrysosperma during fermentation and which accumulate in the culture broth, to a preparation process, to the use of the chrysospermins as pharmacological active compounds, in particular as active compounds against bacteria, fungi and/or nematodes, and for the treatment of rejection reactions in organ transplantations and of tumor disorders, and to the microorganism Apiocrea chrysosperma DSM 7444.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: July 11, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Jorg Metzger, Brigitte Schlegel, Werner F. Fleck, Klausjurgen Dornberger, Wolfgang Ihn, Wolfgang Schade, Udo J. Grafe