Patents by Inventor Werner Hoelzl

Werner Hoelzl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7722893
    Abstract: The use of 2,4—bis(alkylamino)pyrimidines of formula (1) R1 is C1-C12alkyl or C6-C10laryl; R2 is hydrogen or C1-C12alkyl; or R1 and R2 together form a radical of formula (1a) R? and R? are each independently of the other hydrogen, C1-C6alkyl or C1-C6alkoxy, R3 and R5 are each independently of the other hydrogen or C1-C8alkyl; R4 is C1-C20alkyl, unsubstituted phenyl, C6-C10aryl, C6-C10aryl-C1-C6alkyl, hydroxy-C1-C6alkyl, di-C1-C6alkylamino-C 1-C6alkyl, mono-C1-C6alkylamino-C1-C6alkyl, —(CH2)2-(O—(CH2)2)1-4—OH or —(CH2)2—(O—(CH2)2)1-4—NH2; R6 is C1-C20alkyl, C6-C10aryl, C6-C10aryl-C1-C6alkyl, hydroxy-C1-C6alkyl, di-C1C6alkylamino-C1-C6alkyl, mono- C1-C6alkylamino-C1-C 6alkyl, —(CH2)2—(O—(CH2)2)1-4—OH or —(CH2)2—(O—(CH2)2)1-4—NH2; or R3 and R 4 and/or R5 and R6, together form a pyrrolidine, piperidine, hexamethyleneimine or morpholine ring; in the antimicrobial treatment of surfaces.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: May 25, 2010
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Sophie Marquais-Bienewald, Werner Hölzl, Andrea Preuss, Andreas Mehlin
  • Patent number: 7476753
    Abstract: Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R1 is hydrogen, C1-C20alkyl; C1-C20alkoxy; CF3; C6-C10aryl; or a radical of formula (1a) and R2 is hydrogen; or C1-C20alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.
    Type: Grant
    Filed: July 19, 2004
    Date of Patent: January 13, 2009
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Dinesh Narendra Rele, Harjinder Singh Bhatti, Werner Hölzl, Sophie Marquais-Bienewald, Errol Vincent Mathias, Andrea Preuss, Barbara Wagner
  • Patent number: 7208597
    Abstract: Triazine derivatives of formula (1) wherein R1 is C1–C20alkyl; C3–C7cycloalkyl; or C1–C20perfluoroalkyl; R2 is hydrogen; C1–C20alkyl; or C3–C7cycloalkyl; and R3 is hydrogen; C1–C20alkyl; C3–C7cycloalky; C1–C20perfluoroalky; C1C20alkyl-carbonyl; C3–C7cycloalkyl-carbonyl; C1–C20perfluoroalkyl-carbonyl; or phenylcarbonyl; are described. The compounds exhibit pronounced action against gram-positive and gram-negative bacteria and also against yeasts and moulds.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: April 24, 2007
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Gabriele Eichacker, Andrea Preuss
  • Publication number: 20060228965
    Abstract: Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R1 is hydrogen, C1-C20alkyl; C1-C20alkoxy; CF3; C6-C10aryl; or a radical of formula (1a) and R2 is hydrogen; or C1-C20alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.
    Type: Application
    Filed: July 19, 2004
    Publication date: October 12, 2006
    Inventors: Dinesh Rele, Harjinder Bhatti, Werner Hölzl, Sophie Marquais-Bienewald, Errol Mathias, Andreas Preuss, Barbara Wagner
  • Patent number: 7105577
    Abstract: The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds.
    Type: Grant
    Filed: April 2, 2004
    Date of Patent: September 12, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna, Mangesh Shivram Sawant, Asawari Bhikaji Mahtre
  • Patent number: 7078550
    Abstract: There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6 and R7 are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3 and n is 0 or 1.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: July 18, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold
  • Patent number: 7015228
    Abstract: Compounds of formula wherein R1 and R2 are each independently of the other hydrogen; unsubstituted or mono- or poly-halo-substituted C1–C20alkyl, C1–C20alkoxy, C2–C20alkenyl, C2–C20alkynyl, C3–C18cycloalkyl, C3–C7cycloalkyl-C1–C20alkyl; hydroxy; C1–C6alkoxy-C1–C20alkyl; carboxy; C1–C6alkyloxycarbonyl; cyano; mono- or di-C1–C20alkylamino; C1–C6alkylamino-C1–C20alkyl; halogen; phenyl; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted phenyl-C1–C20alkyl, phenoxy or phenyl-C1–C20alkoxy; or R1 and R2 form a polymethylene chain of formula —(CH2)m— wherein m=2–12; R3 is unsubstituted C7–C20alkyl; or amino-, hydroxy-, carboxy- or C1–C6alkyloxycarbonyl-substituted C2–C20alkyl; C8–C18cycloalkyl; C8–C20alkenyl; C8–C20alkynyl; C3–C7cycloalkyl-C8–C20alkyl; C1–C4alkoxy-C8–C20alkyl; R7R8N—C7–C20alkyl; phenyl; phenyl-C1–C4alkyl; or phenyl-C1–C4alkoxy; R4 is hydrogen; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted C1–C20alkyl, C2–C20alkenyl, C2–C20alkynyl, C3–C20cycloalkyl, C3–C7cycloalkyl-C1–C20alky
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: March 21, 2006
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Werner Hölzl, Karin Petzold
  • Patent number: 6967215
    Abstract: Tetrahydrocarbazoles of formula where Q is —SO2—; —O—; or —(CO)—; X is —(CH)—; or —N—; m is from 1 to 3; t is 0 or 1 and the remaining substituents are as defined herein, are useful as antimicrobial active ingredients.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: November 22, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Andreas Mehlin, Karin Petzold, Dietmar Ochs, Werner Hölzl
  • Patent number: 6846492
    Abstract: The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl,
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: January 25, 2005
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Werner Hölzl, Dietmar Ochs, Karin Petzold, Marcel Schnyder
  • Patent number: 6814960
    Abstract: The use of hydroxystilbene compounds of formula wherein A is a radical of formula  or a radical of formula  and R1, R2, R3, R4 and R5 are each independently of the others hydrogen, halogen, hydroxy, C1-C16alkyl, C1-C16alkoxy, phenyl; C1-C3phenylalkyl; C6-C10aryloxy, amino, mono-C1-C5alkylamino, di-C1-C5alkylamino, or —NO2; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are therefore suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: November 9, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Dietmar Ochs, Wolfgang Haap, Karin Puchtler, Marc I Schnyder
  • Patent number: 6759423
    Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.
    Type: Grant
    Filed: October 3, 2001
    Date of Patent: July 6, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Dinesh Narendra Rele, Sitaram Pal, Asawari Bhikaji Mahtre, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna
  • Patent number: 6743940
    Abstract: There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds.
    Type: Grant
    Filed: December 13, 2001
    Date of Patent: June 1, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold, Dietmar Ochs, Karin Petzold, Marcel Schnyder
  • Patent number: 6706930
    Abstract: There is described a process for the preparation of halogenated hydroxydiphenyl compounds of formula (1) by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound, which is not further substituted in the ortho-position (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, wherein the reaction of the second stage is carried out in the presence of K2CO3 and any desired copper catalyst, where K2CO3 is used in a concentration of from 0.5 to 30 mol, based on the phenol compound employed of formula (6), according to the reaction scheme (I) in which R1 and R2 independently of one another are F, Cl or Br; R3 and R4 independently of one another are hydrogen; or C1-C4alkyl; m is 1 to 3; and n is 1 or 2. The compounds of formula (1) are used for protecting organic materials and articles from microorganisms.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: March 16, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink
  • Patent number: 6689372
    Abstract: The use of oxathiazolones of formula is described R1 is phenyl unsubstituted or substituted by one or more C1-C5 alkyl, hydroxyl, halogen substituents or by a 1,3,4-oxathiazol-2-one radical. in the antimicrobial treatment of surfaces. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds.
    Type: Grant
    Filed: February 1, 2000
    Date of Patent: February 10, 2004
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Marcel Schnyder
  • Patent number: 6624182
    Abstract: The use of hydroxyphenylvinylthiazoles of formula wherein R1, R2, R3 and R4 are each independently of the others hydrogen; halogen; hydroxy, C1-C16-alkyl, C1-C16alkoxy, phenyl; phenyl-C1-C3alkyl; C6-C10aryloxy, amino, mono-C1-C5alkyl-amino, di-C1-C5alkylamino or -NO2; wherein at least one of the radicals R1, R2, R3 and R4 is hydroxy; R5 is C1-C5alkyl; C1-C5alkoxy; or unsubstituted or halo-, C1-C5alkyl-, C1-C5alkoxy-, hydroxy- or pyrrolidinyl-substituted phenyl; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. Accordingly, they are suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.
    Type: Grant
    Filed: November 16, 2000
    Date of Patent: September 23, 2003
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Wolfgang Haap, Werner Hölzl, Dietmar Ochs, Karin Puchtler, Marcel Schnyder
  • Patent number: 6596907
    Abstract: A description is given of a three-step process for the preparation of 4,4′-dihalogen-o-hydroxydiphenyl compounds of formula (1) which comprises: a) hologenating an alkoxyphenol of formula (6) (=a1), reacting the resulting halogenated phenol compound of formula (5) with p-dihalobenzene of formula (4a) in the presence of copper and/or copper salts to the diphenyl ether compound of formula (2) (=a2) and subsequent ether fission to the diphenyl ether compound of formula (1) (=a3); or b) reacting an alkoxyphenol of formula (6) with the halophenol of formula (4b) to the compound of formula (3) (=b1), then halogenating this compound (=b2) and subsequent ether fission of the resulting compound of formula (2) to the diphenyl ether compound of formula (1) (=b3). The compounds of formula (1) are used for protecting organic materials and objects against microorganisms.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: July 22, 2003
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink
  • Patent number: 6376522
    Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: April 23, 2002
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Dinesh Narenda Rele, Sitaram Pal, Asawari Bhikaji Mahtre, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna
  • Patent number: 6365563
    Abstract: A detergent additive is described, which comprises at least one swellable layered silicate, an antimicrobial active substance and a surfactant and, optionally, an alkali salt. This detergent additive is distinguished in that it protects the antimicrobial active substance from oxidation by the bleaches which are usually present in detergents and in that said active substance is only released during the washing process.
    Type: Grant
    Filed: September 15, 1998
    Date of Patent: April 2, 2002
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Rüdiger Hirsch, Werner Hölzl, Marcel Schnyder, Rainer Hans Traber
  • Patent number: 6346260
    Abstract: The use of hydroxyphenyl-1,3-propanediones of formula: wherein R1 and R2 are each independently of the other hydrogen, C1-C12alkyl, C1-C12alkoxy, trifluoro-C1-C3alkyl, phenyl or halogen; R3 is a 5- or 6-membered heteroaromatic radical; thiophenyl; or a radical of formula: R4, R5, R6 and R7 are each independently of the other hydrogen, halogen, C1-C12alkyl, C1-C12alkoxy, carboxy or trifluoro-C1-C3alkyl; in the antimicrobial treatment of surfaces, is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and molds.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: February 12, 2002
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder
  • Patent number: 6215029
    Abstract: A process for the preparation of halohydroxydiphenyl compounds useful for protecting organic materials and articles from microorganisms, of the formula by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, according to the following reaction scheme: in which R1 and R2 independently of one another are F, Cl or Br; R3 and R4 independently of one another are hydrogen; or C1-C4alkyl; m is 1 to 3; and n is 1 or 2.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: April 10, 2001
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Urs Burckhardt, Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink, Hanspeter Sauter, Uwe Gronde