Patents by Inventor Werner Hoelzl
Werner Hoelzl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7722893Abstract: The use of 2,4—bis(alkylamino)pyrimidines of formula (1) R1 is C1-C12alkyl or C6-C10laryl; R2 is hydrogen or C1-C12alkyl; or R1 and R2 together form a radical of formula (1a) R? and R? are each independently of the other hydrogen, C1-C6alkyl or C1-C6alkoxy, R3 and R5 are each independently of the other hydrogen or C1-C8alkyl; R4 is C1-C20alkyl, unsubstituted phenyl, C6-C10aryl, C6-C10aryl-C1-C6alkyl, hydroxy-C1-C6alkyl, di-C1-C6alkylamino-C 1-C6alkyl, mono-C1-C6alkylamino-C1-C6alkyl, —(CH2)2-(O—(CH2)2)1-4—OH or —(CH2)2—(O—(CH2)2)1-4—NH2; R6 is C1-C20alkyl, C6-C10aryl, C6-C10aryl-C1-C6alkyl, hydroxy-C1-C6alkyl, di-C1C6alkylamino-C1-C6alkyl, mono- C1-C6alkylamino-C1-C 6alkyl, —(CH2)2—(O—(CH2)2)1-4—OH or —(CH2)2—(O—(CH2)2)1-4—NH2; or R3 and R 4 and/or R5 and R6, together form a pyrrolidine, piperidine, hexamethyleneimine or morpholine ring; in the antimicrobial treatment of surfaces.Type: GrantFiled: July 16, 2004Date of Patent: May 25, 2010Assignee: Ciba Specialty Chemicals CorporationInventors: Sophie Marquais-Bienewald, Werner Hölzl, Andrea Preuss, Andreas Mehlin
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Patent number: 7476753Abstract: Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R1 is hydrogen, C1-C20alkyl; C1-C20alkoxy; CF3; C6-C10aryl; or a radical of formula (1a) and R2 is hydrogen; or C1-C20alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.Type: GrantFiled: July 19, 2004Date of Patent: January 13, 2009Assignee: Ciba Specialty Chemicals CorporationInventors: Dinesh Narendra Rele, Harjinder Singh Bhatti, Werner Hölzl, Sophie Marquais-Bienewald, Errol Vincent Mathias, Andrea Preuss, Barbara Wagner
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Patent number: 7208597Abstract: Triazine derivatives of formula (1) wherein R1 is C1–C20alkyl; C3–C7cycloalkyl; or C1–C20perfluoroalkyl; R2 is hydrogen; C1–C20alkyl; or C3–C7cycloalkyl; and R3 is hydrogen; C1–C20alkyl; C3–C7cycloalky; C1–C20perfluoroalky; C1C20alkyl-carbonyl; C3–C7cycloalkyl-carbonyl; C1–C20perfluoroalkyl-carbonyl; or phenylcarbonyl; are described. The compounds exhibit pronounced action against gram-positive and gram-negative bacteria and also against yeasts and moulds.Type: GrantFiled: July 22, 2003Date of Patent: April 24, 2007Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Gabriele Eichacker, Andrea Preuss
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Publication number: 20060228965Abstract: Disclosed are 3-aryl-2-cyano-3-hydroxy-acrylic acid derivates of formula(1a) (1b) or (1c) wherein R1 is hydrogen, C1-C20alkyl; C1-C20alkoxy; CF3; C6-C10aryl; or a radical of formula (1a) and R2 is hydrogen; or C1-C20alkyl. The compounds are used as antimicrobial actives for the treatment of surfaces.Type: ApplicationFiled: July 19, 2004Publication date: October 12, 2006Inventors: Dinesh Rele, Harjinder Bhatti, Werner Hölzl, Sophie Marquais-Bienewald, Errol Mathias, Andreas Preuss, Barbara Wagner
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Patent number: 7105577Abstract: The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these compounds.Type: GrantFiled: April 2, 2004Date of Patent: September 12, 2006Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna, Mangesh Shivram Sawant, Asawari Bhikaji Mahtre
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Patent number: 7078550Abstract: There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6 and R7 are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3 and n is 0 or 1.Type: GrantFiled: January 10, 2002Date of Patent: July 18, 2006Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold
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Patent number: 7015228Abstract: Compounds of formula wherein R1 and R2 are each independently of the other hydrogen; unsubstituted or mono- or poly-halo-substituted C1–C20alkyl, C1–C20alkoxy, C2–C20alkenyl, C2–C20alkynyl, C3–C18cycloalkyl, C3–C7cycloalkyl-C1–C20alkyl; hydroxy; C1–C6alkoxy-C1–C20alkyl; carboxy; C1–C6alkyloxycarbonyl; cyano; mono- or di-C1–C20alkylamino; C1–C6alkylamino-C1–C20alkyl; halogen; phenyl; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted phenyl-C1–C20alkyl, phenoxy or phenyl-C1–C20alkoxy; or R1 and R2 form a polymethylene chain of formula —(CH2)m— wherein m=2–12; R3 is unsubstituted C7–C20alkyl; or amino-, hydroxy-, carboxy- or C1–C6alkyloxycarbonyl-substituted C2–C20alkyl; C8–C18cycloalkyl; C8–C20alkenyl; C8–C20alkynyl; C3–C7cycloalkyl-C8–C20alkyl; C1–C4alkoxy-C8–C20alkyl; R7R8N—C7–C20alkyl; phenyl; phenyl-C1–C4alkyl; or phenyl-C1–C4alkoxy; R4 is hydrogen; unsubstituted or C1–C5alkyl-, halo- or hydroxy-substituted C1–C20alkyl, C2–C20alkenyl, C2–C20alkynyl, C3–C20cycloalkyl, C3–C7cycloalkyl-C1–C20alkyType: GrantFiled: April 17, 2002Date of Patent: March 21, 2006Assignee: Ciba Specialty Chemicals CorporationInventors: Wolfgang Haap, Werner Hölzl, Karin Petzold
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Patent number: 6967215Abstract: Tetrahydrocarbazoles of formula where Q is —SO2—; —O—; or —(CO)—; X is —(CH)—; or —N—; m is from 1 to 3; t is 0 or 1 and the remaining substituents are as defined herein, are useful as antimicrobial active ingredients.Type: GrantFiled: September 11, 2001Date of Patent: November 22, 2005Assignee: Ciba Specialty Chemicals CorporationInventors: Wolfgang Haap, Andreas Mehlin, Karin Petzold, Dietmar Ochs, Werner Hölzl
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Patent number: 6846492Abstract: The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20alkenyl; C4-C7cycloalkenyl; C2-C20alkynyl, C4-C7cycloalkynyl; or unsubstituted or C1-C5alkyl-, C3-C7cylcoalkyl-, C1-C5alkoxyl-, C3-C7cycloakoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C7cylcloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl-C1-C5alkyl, naphthyl-C1-C5alkyl, phenylcarbonyl-C1-C5alkyl, naphthylcarbonyl-C1-C5alkyl, pyrrolylalkyl, furanylalkyl, thiophenylalkyl, pyrazolylalkyl, imidazolylalkyl, oxazolylalkyl, thiazolylalkyl, isoxazolylalkyl, isothiazolylalkyl, 1,2,3-triazolylalkyl, 1,2,4-triazolylalkyl, 1,2,3-oxadiazolylalkyl, 1,3,4-oxadiazolylalkyl, 1,2,3-thiadiazolylalkyl, 1,3,4-thiadiazolylalkyl, indolylalkyl, pyridylalkyl, pyridazinylalkyl, pyrimidinylalkyl, pyridazinylalkyl, quinolinylalkyl, isoquinolinylalkyl, pyrrolyl, furanyl,Type: GrantFiled: February 13, 2001Date of Patent: January 25, 2005Assignee: Ciba Specialty Chemicals CorporationInventors: Wolfgang Haap, Werner Hölzl, Dietmar Ochs, Karin Petzold, Marcel Schnyder
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Patent number: 6814960Abstract: The use of hydroxystilbene compounds of formula wherein A is a radical of formula or a radical of formula and R1, R2, R3, R4 and R5 are each independently of the others hydrogen, halogen, hydroxy, C1-C16alkyl, C1-C16alkoxy, phenyl; C1-C3phenylalkyl; C6-C10aryloxy, amino, mono-C1-C5alkylamino, di-C1-C5alkylamino, or —NO2; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. They are therefore suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.Type: GrantFiled: April 5, 2001Date of Patent: November 9, 2004Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Dietmar Ochs, Wolfgang Haap, Karin Puchtler, Marc I Schnyder
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Patent number: 6759423Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.Type: GrantFiled: October 3, 2001Date of Patent: July 6, 2004Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Dinesh Narendra Rele, Sitaram Pal, Asawari Bhikaji Mahtre, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna
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Patent number: 6743940Abstract: There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C12cycloalkyl; unsubstituted or C1-C5alkyl-, C3-C12cycloalkyl-, C1-C5alkoxy-, C3-C12cycloalkoxy-, halo-, oxo-, carboxy-, carboxy-C1-C7alkyl ester-, carboxy-C3-C12cycloalkyl ester-, cyano-, trifluoromethyl-, pentafluoroethyl-, amino-, N,N-mono- or di-C1-C20alkylamino- or nitro-substituted phenyl, phenyl-C1-C5alkyl, naphthyl and naphthyl-C1-C5alkyl; and R3 is C1-C20alkyl; C3-C12cycloalkyl. The compounds exhibit a pronounced activity against gram-positive and gram-negative bacteria, and also against yeasts and moulds.Type: GrantFiled: December 13, 2001Date of Patent: June 1, 2004Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Jürgen Koppold, Dietmar Ochs, Karin Petzold, Marcel Schnyder
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Patent number: 6706930Abstract: There is described a process for the preparation of halogenated hydroxydiphenyl compounds of formula (1) by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound, which is not further substituted in the ortho-position (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, wherein the reaction of the second stage is carried out in the presence of K2CO3 and any desired copper catalyst, where K2CO3 is used in a concentration of from 0.5 to 30 mol, based on the phenol compound employed of formula (6), according to the reaction scheme (I) in which R1 and R2 independently of one another are F, Cl or Br; R3 and R4 independently of one another are hydrogen; or C1-C4alkyl; m is 1 to 3; and n is 1 or 2. The compounds of formula (1) are used for protecting organic materials and articles from microorganisms.Type: GrantFiled: October 31, 2002Date of Patent: March 16, 2004Assignee: Ciba Specialty Chemicals CorporationInventors: Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink
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Patent number: 6689372Abstract: The use of oxathiazolones of formula is described R1 is phenyl unsubstituted or substituted by one or more C1-C5 alkyl, hydroxyl, halogen substituents or by a 1,3,4-oxathiazol-2-one radical. in the antimicrobial treatment of surfaces. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds.Type: GrantFiled: February 1, 2000Date of Patent: February 10, 2004Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Marcel Schnyder
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Patent number: 6624182Abstract: The use of hydroxyphenylvinylthiazoles of formula wherein R1, R2, R3 and R4 are each independently of the others hydrogen; halogen; hydroxy, C1-C16-alkyl, C1-C16alkoxy, phenyl; phenyl-C1-C3alkyl; C6-C10aryloxy, amino, mono-C1-C5alkyl-amino, di-C1-C5alkylamino or -NO2; wherein at least one of the radicals R1, R2, R3 and R4 is hydroxy; R5 is C1-C5alkyl; C1-C5alkoxy; or unsubstituted or halo-, C1-C5alkyl-, C1-C5alkoxy-, hydroxy- or pyrrolidinyl-substituted phenyl; as microbicidal active ingredients is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and moulds. Accordingly, they are suitable for the antimicrobial treatment, especially the preservation and disinfection, of surfaces.Type: GrantFiled: November 16, 2000Date of Patent: September 23, 2003Assignee: Ciba Specialty Chemicals CorporationInventors: Wolfgang Haap, Werner Hölzl, Dietmar Ochs, Karin Puchtler, Marcel Schnyder
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Patent number: 6596907Abstract: A description is given of a three-step process for the preparation of 4,4′-dihalogen-o-hydroxydiphenyl compounds of formula (1) which comprises: a) hologenating an alkoxyphenol of formula (6) (=a1), reacting the resulting halogenated phenol compound of formula (5) with p-dihalobenzene of formula (4a) in the presence of copper and/or copper salts to the diphenyl ether compound of formula (2) (=a2) and subsequent ether fission to the diphenyl ether compound of formula (1) (=a3); or b) reacting an alkoxyphenol of formula (6) with the halophenol of formula (4b) to the compound of formula (3) (=b1), then halogenating this compound (=b2) and subsequent ether fission of the resulting compound of formula (2) to the diphenyl ether compound of formula (1) (=b3). The compounds of formula (1) are used for protecting organic materials and objects against microorganisms.Type: GrantFiled: April 3, 2001Date of Patent: July 22, 2003Assignee: Ciba Specialty Chemicals CorporationInventors: Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink
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Patent number: 6376522Abstract: The present invention relates to the use of 4-hydroxyisothiazole compounds as antimicrobially active substances, certain new 4-hydroxyisothiazole compounds and a process for their preparation.Type: GrantFiled: May 18, 2000Date of Patent: April 23, 2002Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder, Dinesh Narenda Rele, Sitaram Pal, Asawari Bhikaji Mahtre, Surendra Umesh Kulkarni, Arakali Srinivasarao Radhakrishna
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Patent number: 6365563Abstract: A detergent additive is described, which comprises at least one swellable layered silicate, an antimicrobial active substance and a surfactant and, optionally, an alkali salt. This detergent additive is distinguished in that it protects the antimicrobial active substance from oxidation by the bleaches which are usually present in detergents and in that said active substance is only released during the washing process.Type: GrantFiled: September 15, 1998Date of Patent: April 2, 2002Assignee: Ciba Specialty Chemicals CorporationInventors: Rüdiger Hirsch, Werner Hölzl, Marcel Schnyder, Rainer Hans Traber
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Patent number: 6346260Abstract: The use of hydroxyphenyl-1,3-propanediones of formula: wherein R1 and R2 are each independently of the other hydrogen, C1-C12alkyl, C1-C12alkoxy, trifluoro-C1-C3alkyl, phenyl or halogen; R3 is a 5- or 6-membered heteroaromatic radical; thiophenyl; or a radical of formula: R4, R5, R6 and R7 are each independently of the other hydrogen, halogen, C1-C12alkyl, C1-C12alkoxy, carboxy or trifluoro-C1-C3alkyl; in the antimicrobial treatment of surfaces, is described. The compounds exhibit a pronounced action against pathogenic gram-positive and gram-negative bacteria, and also against yeasts and molds.Type: GrantFiled: August 1, 2000Date of Patent: February 12, 2002Assignee: Ciba Specialty Chemicals CorporationInventors: Werner Hölzl, Wolfgang Haap, Dietmar Ochs, Karin Puchtler, Marcel Schnyder
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Patent number: 6215029Abstract: A process for the preparation of halohydroxydiphenyl compounds useful for protecting organic materials and articles from microorganisms, of the formula by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, according to the following reaction scheme: in which R1 and R2 independently of one another are F, Cl or Br; R3 and R4 independently of one another are hydrogen; or C1-C4alkyl; m is 1 to 3; and n is 1 or 2.Type: GrantFiled: June 9, 1999Date of Patent: April 10, 2001Assignee: Ciba Specialty Chemicals CorporationInventors: Urs Burckhardt, Armando Di Teodoro, Werner Hölzl, Dieter Reinehr, Rudolf Zink, Hanspeter Sauter, Uwe Gronde