Patents by Inventor Werner J. Geldenhuys

Werner J. Geldenhuys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190388381
    Abstract: Methods of inhibiting formation of complexes of CDGSH iron-sulfur domain (CISD) protein and pyridoxal-5?-phosphate (PLP) are provided herein. More specifically, methods of inhibiting formation of CISD protein-PLP complexes include exposing a CISD protein to a compound with specific binding affinity for a designated lysine residue in the CISD protein. Inhibition of CISD protein-PLP complex formation is relevant to disease states associated with the CISD protein-PLP complex.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Inventors: Mary E. Konkle, Michael A. Menze, Werner J. Geldenhuys
  • Publication number: 20090143457
    Abstract: Described herein are various compounds for treatment of ocular neurodegenerative diseases, including but not limited to glaucoma and diabetic retinopathy. The compounds described herein can act to attenuate and/or block calcium release from external neuronal environments as well as intracellular stores.
    Type: Application
    Filed: December 4, 2008
    Publication date: June 4, 2009
    Applicant: NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE
    Inventors: Cornelis J. Van der Schyf, Randolph B. Schiffer, Paula Grammas, Masao Roy Wilson, Werner J. Geldenhuys, Lois-May Bezuidenhout